Navigation Links
Researchers propose measures to curb lion attacks in Tanzania

A breakthrough in human stem cell research, producing embryonic-like cells from umbilical cord blood may substantially speed up the development of treatments for life-threatening illnesses, injuries and disabilities. The discovery made during a project undertaken with experts from the University of Texas Medical Branch and the Synthecon Corporation in the United States provides medical researchers and physicians with an ethical and reliable source of human stem cells for the first time.

The study, funded by the UK Government's Department of Trade and Industry, is led by Dr Colin McGuckin and Dr Nico Forraz from Kingston University's School of Life Sciences. It represents a significant step forward in the fast-developing field of stem cell research. Until now, experts have struggled to find a supply of cells in sufficient numbers that does not offend previous critics of stem cell research. The latest advance looks set to overcome such difficulties.

The trans-Atlantic team has been working with Drs Randall Urban, Larry Denner and Ronald Tilton from the University of Texas Medical Branch in Galveston. They have been using bioreactors at the Synthecon Corporation base in Houston enabling them to produce stem cells sharing many of the same characteristics as cells found in embryos. Research has so far relied on so-called adult cells found in blood and bone marrow from birth onwards or cells grown from embryos. The new type detected by the team harnesses the benefits of both. "We have found a unique group of cells that bring together the essential qualities of both types of stem cells for the first time," Dr McGuckin said.

The researchers findings may bring renewed hope to people awaiting treatment for a range of serious illnesses such as Diabetes, Alzheimer's Disease and multiple sclerosis. "Acquiring stem cells from embryos also has major limitations because it is difficult to obtain enough cells to transplant as well as getting the right tissue type for the patient," Dr McGuckin said. "Using cord blood gets over that obstacle because we can produce more stem cells and, with a global birth rate of 100 million babies a year, there is a better chance of getting the right tissue type for the many patients out there waiting for stem cell therapy. There is also far less likelihood of such cells being rejected when they are transplanted into people with liver disease, for example."

The team has taken its first steps towards proving its claims by growing defined liver tissue using the new cell type. By making use of special NASA-derived technology, the team is able to cultivate greater numbers of cells in equipment mimicking the effects of space microgravity. "Using Synthecon's bioreactors, originally designed by NASA, means the cells are able to expand faster, giving us a greater supply to work with," Dr Forraz said. "This system provides more cells for more tests, so we have the potential to make significant progress in applying the new cells to cure difficult to treat conditions such as juvenile diabetes, stroke, heart and liver disease."

Dr Urban who chairs UTMB's Internal Medicine department and serves as director of its Stark Diabetes Centre said he looked forward to the next phase of what was proving to be a fruitful collaboration. "We plan to use this technology to engineer pancreatic tissue as we work towards our goal of developing a cure for type 1 diabetes," he added.

The team's report will be published in the Cell Proliferation Journal on 18 August.



Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:

(Date:10/29/2015)... 2015   MedNet Solutions , an innovative SaaS-based ... clinical research, is pleased to announce that it has ... as one of only three finalists for a ... and Growing" category. The Tekne Awards honor Minnesota ... technology innovation and leadership. iMedNet™ eClinical ...
(Date:10/29/2015)... , Oct. 29, 2015 Daon, a ... that it has released a new version of its ... in North America have already ... v4.0 also includes a FIDO UAF certified server ... already preparing to activate FIDO features. These customers include ...
(Date:10/29/2015)... , Oct. 29, 2015  Connected health pioneer, ... driving the explosion of technology-enabled health and wellness, and ... new book, The Internet of Healthy Things ... sensors or smartphones even existed, Dr. Kvedar, vice president, ... of health care delivery, moving care from the hospital ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... , Nov. 25, 2015  PharmAthene, Inc. (NYSE ... has adopted a stockholder rights plan (Rights Plan) in ... operating loss carryforwards (NOLs) under Section 382 of the ... --> PharmAthene,s use of its NOLs could ... change" as defined in Section 382 of the Code. ...
(Date:11/25/2015)... -- Studies reveal the differences in species ... the way for more effective treatment for one of the ... --> --> Gum disease ... cats, yet relatively little was understood about the bacteria associated ... conducted by researchers from the WALTHAM Centre for Pet Nutrition ...
(Date:11/25/2015)... , Nov. 25, 2015  Neurocrine Biosciences, Inc. (Nasdaq: ... , President and CEO of Neurocrine Biosciences, will be ... in New York . ... the website approximately 5 minutes prior to the presentation ... of the presentation will be available on the website ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... Organization of Black Aerospace Professionals (OPBAP) has been formalized with the signing of ... team leaders met with OPBAP leaders Capt. Karl Minter and Capt. Albert Glenn ...
Breaking Biology Technology: