Navigation Links
Researchers offer proof-of-concept for Altered Nuclear Transfer

Scientists at Whitehead Institute for Biomedical Research have successfully demonstrated that a theoretical--and controversial--technique for generating embryonic stem cells is indeed possible, at least in mice.

The theory, called altered nuclear transfer (ANT), proposes that researchers first create genetically altered embryos that are unable to implant in a uterus, and then extract stem cells from these embryos. Because the embryos cannot implant, they are by definition not "potential" human lives. Some suggest that this would quell the protests of critics who claim that embryonic stem cell research necessitates the destruction of human life. Scientists and ethicists have debated the merits of this approach, but so far it has not been achieved.

"The purpose of our study was to provide a scientific basis for the ethical debate," says Whitehead Member Rudolf Jaenisch, lead author on the paper that will be published in the October 16 online edition of the journal Nature. "Our work is the first proof-of-principle study to show that altered nuclear transfer not only works but is extremely efficient."

First proposed by William Hurlbut, Stanford University professor and member of the President's Council on Bioethics, ANT has been described as an ethical alternative to somatic cell nuclear transfer (SCNT), also known as therapeutic cloning.

For SCNT, a donor nucleus, for example one taken from a skin cell, is implanted into a donor egg cell from which the nucleus had been removed. This egg cell is then tricked into thinking it has been fertilized. That causes it to grow into a blastocyst--a mass of about 100 cells--from which stem cells are removed. These embryonic stem cells can divide and replicate themselves indefinitely, and they can also form any type of tissue in the human body. However, to cull these stem cells, the blastocyst must be destroyed, which some critics insist is tantamount to destroying a human life.

The proce
'"/>

Source:Whitehead Institute for Biomedical Research


Page: 1 2 3

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers offer proof concept for Altered Nuclear Transfer

(Date:3/12/2015)... 2015 The mascots of the Atlantic Coast ... of Wake Forest Baptist Medical Center. They stopped by ... ACC Men,s Basketball Tournament. Young patients enjoyed bonding with ... their autographs. Brenner Children,s Hospital is the ... only children,s hospital in northwest North Carolina ...
(Date:3/11/2015)... , Mar. 11, 2015 Research and Markets ... the "Access Control Market by Product, Application & ... report to their offering. , This ... to reach $10.4 billion by 2020, with an estimated ... report covers the products types such as contact cards ...
(Date:3/10/2015)... , March 10, 2015 Transforming ... "Personalized Medicine in Human Space Flight" ... Thomas J. Goodwin , Ph.D. was recently featured by ... past two years. Specifically, "Personalized Medicine in ... scientific papers published in 2013 and 2014 from Springer ...
Breaking Biology News(10 mins):Global Access Control (Cards & Readers, Biometrics, Controllers, Management Software) Market 2015-2020 - Analysis of the $10 Billion Market 2"Personalized Medicine in Human Space Flight" Listed Among Most Influential Papers of 2013 and 2014 2
... Ohio scientists hope to counter the re-emerging threat of ... a research report published in the June 2010 print issue ... ), scientists show how the protein CCL5 plays a protective ... disease in the early stages of infection. CCL5 is a ...
... California, San Diego have identified a previously unknown kinase that ... major role in the progression or metastasis of cancer cells. ... 31 online Early Edition of the Proceedings of the ... professor of pathology at the UCSD School of Medicine and ...
... There have been impressive advances in computational methods, allowing ... the atomic level. In its latest Perspectives in General ... (JGP) offers an in-depth look at several of these ... membrane proteins, with special focus on ion channels. The ...
Cached Biology News:Body's own proteins may lead the way in global fight against tuberculosis 2Newly discovered kinase regulates cytoskeleton, and perhaps holds key to how cancer cells spread 2
(Date:3/31/2015)... MONMOUTH JUNCTION, N.J., March 31, 2015 ... immunotherapy company using blood purification to treat critically-ill ... provides an operational summary and reports financial results ... 2014 CytoSorb® product revenues were ... 281%, compared to 2013 CytoSorb® revenues of $0.8M ...
(Date:3/31/2015)... VANCOUVER , March 31, 2015  /PRNewswire/ ... announced today that it has filed with the Food ... New Drug ("IND") application related to the Company,s proposed ... of the IND application is required in order for ... US.  The IND application is a ...
(Date:3/31/2015)... OXFORD, England , March 31, 2015 ... Singapore ,   June 30 2015   ... technical and medical information products and services and publishing home ... Science Council has launched the Materials in ... be presented during the 8 th International Conference ...
(Date:3/31/2015)... FRANCISCO , March 31, 2015  Sonoa Health, ... Australia , has developed a world-first consumer health ... records, medication prescriptions, wearable devices and more. ... Stewart as its CEO, who brings to the ... corporate advisory, which has included working closely with the ...
Breaking Biology Technology:CytoSorbents Reports Record 2014 Revenue 2CytoSorbents Reports Record 2014 Revenue 3CytoSorbents Reports Record 2014 Revenue 4CytoSorbents Reports Record 2014 Revenue 5CytoSorbents Reports Record 2014 Revenue 6CytoSorbents Reports Record 2014 Revenue 7CytoSorbents Reports Record 2014 Revenue 8CytoSorbents Reports Record 2014 Revenue 9CytoSorbents Reports Record 2014 Revenue 10CytoSorbents Reports Record 2014 Revenue 11ESSA Pharma Inc. Announces Filing of Investigational New Drug Application for EPI-506 2ESSA Pharma Inc. Announces Filing of Investigational New Drug Application for EPI-506 3ESSA Pharma Inc. Announces Filing of Investigational New Drug Application for EPI-506 4Elsevier Materials Science Council Introduces the Materials in Society Lecture Series at the International Conference on Materials for Advanced Technologies (ICMAT) 2Elsevier Materials Science Council Introduces the Materials in Society Lecture Series at the International Conference on Materials for Advanced Technologies (ICMAT) 3Investment Banker Appointed CEO of Australian Health Tech Start-Up 2Investment Banker Appointed CEO of Australian Health Tech Start-Up 3
... Although Madison has made a deal with Georgia-based Cellnet ... not be an overnight event. Certain areas will be initially ... Square expected to be approved by the City Council in ... of Madison has taken an active role in brokering Cellnets ...
... State of Wisconsin Investment Board , which manages the 10th ... that it has preliminary approval to put up to $50 million ... between Mason Wells Biomedical Fund II and Venture ... investments with both firms $45 split between the two in ...
... recent phase-one study at UW-Madisons Waisman Center shows a ... and other neurodegenerative disorders. Their treatment could enable brain ... the bodys movement, to recover from the damage caused ... naturally occurring protein in the brain called glial cell-derived ...
Cached Biology Technology:Madison wireless deal goes forward with Cellnet 2Stem cells produce anti-disease protein in brain experiment 2
... The nature of proteomics demands the ... The superior performance of the AXIMA-CFRplus with ... than 5 ppm) provides increased confidence in ... blanking for enhanced sensitivity, automated sample target ...
QCPN...
... standard of the Axima range, the ... mass accuracy, resolution, sensitivity and mass ... both linear and reflectron time-of-flight analysis. ... enables the generation of seamless PSD, ...
... O-TOF creates a new category for MALDI. ... that has been licensed to the PerkinElmerSCIEX ... , As the first single MALDI-TOF mass ... cooling, the prOTOF 2000 represents a substantial ...
Biology Products: