Navigation Links
Researchers make surprise discovery that some neurons can transmit three signals at once

Generations of neuroscientists have been indoctrinated into believing that our senses, thoughts, feelings and movements are orchestrated by a communication network of brain cells, or neurons, each responsible for relaying one specific chemical message called a neurotransmitter. Either neurons release a neurotransmitter that excites a neighboring cell, thereby triggering an electrical discharge and enhancing brain activity, or they dispatch a signal that quells a neuron's activity. So, when researchers at the University of Pittsburgh discovered that immature rat brain cells could fire a simultaneous three-punch salvo ?three neurotransmitters bursting out of a single cell -- it was a finding they knew would excite more than just neurons.

Just as surprising, they report in the lead article of this month's Nature Neuroscience, is that by definition these three neurotransmitters are seemingly at odds with each other. One, glutamate, is a textbook excitatory neurotransmitter; while the other two, GABA and glycine, are quintessential inhibitory neurotransmitters.

Information is transmitted between neurons when one cell releases a neurotransmitter at a synapse, the point of contact between cells. When released from a cell, neurotransmitters are sent on a one-way ride that dead ends at the membrane of the adjacent cell. Like lock and key, they bind to specific receptors on the surface of the receiving cell, causing its electrical activity to be enhanced or inhibited.

The first week after birth marks a critical phase in the developing rat brain, a time period comparable to three months gestation in a human, when neurons are meticulously organizing and self-selecting to assemble into specific brain structures and neuronal networks. It has long been known that a specific receptor for glutamate, the NMDA receptor, plays a crucial role in these processes, but how inhibitory synapses, which account for about half of the brain's cellular connections, would ga
'"/>

Source:University of Pittsburgh Medical Center


Page: 1 2 3

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
(Date:1/22/2015)... Jan. 9, 2015 Valid S.A. ("Company") (BM&FBOVESPA: VLID3 ON), ... general the State of Washington,s Department ... new enrollment and central issuance system for driver,s licenses and ... The project planning and development will start in January 2015, ...
(Date:1/22/2015)... Showcase, Hall E -   EyeLock Inc. , a market ... showcase its EyeLock ID technology integrated in a 3D printed ... Oak Ridge National Laboratory (ORNL) at the 2015 ... technology is being used to validate the driver and authorize ...
(Date:1/22/2015)... , Jan. 20, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... commerce market, reports on the recent success of the Wocket™ smart wallet ... Wocket smart wallet was named as one of the "11 Hot ... "5 Best Products Launched At CES So Far" by Newseveryday.com and "The ...
Breaking Biology News(10 mins):Valid USA Signs Contract For Washington Driver's License Issuance 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3
... Restoration International (SER) released its May 2008 Briefing ... & Biological Conservation within the Ecosystem Approach at ... the Parties held in Bonn, Germany, May 19-30, ... Ecosystem Approach, as developed by the CBD and ...
... and Technology (NIST) have reported* a new technique to ... centrifuges. Many potential applications for carbon nanotubes depend on ... the most important features of the new technique, say ... to produce industrial quantities of high-quality nanotubes. ...
... of shipments involving regulated radioactive materials used in medicine ... industry experts. Meeting in Rome this week at an ... the Mediterranean region that seeks to ease hardships for ... delivery of beneficial radiation sources. The shipment issues ...
Cached Biology News:Integrating restoration and conservation within the ecosystem approach 2Spin control: New technique sorts nanotubes by length 2Experts tackle shipment issues for beneficial radiation sources 2Experts tackle shipment issues for beneficial radiation sources 3
(Date:12/24/2014)... DALLAS and NEW YORK , ... a biopharmaceutical company advancing patient care in critical areas, announced ... of common stock, and warrants to purchase up to an ... of $4.00 per share and $.01 per warrant.  The warrants ...
(Date:12/24/2014)... “Preparative & Process Chromatography Market ... (Columns, Solvents, Buffers, Valves, Guages, Seals), Accessories, Services, ... Forecasts to 2019” provides a detailed overview of ... trends, and strategies impacting the preparative and process ...
(Date:12/24/2014)... SoundConnect’s 2015 next ... edge communication technology, provide continued education and inform ... series demonstrates online communication features and benefits; empowering ... most innovative and powerful tools. , According to ...
(Date:12/24/2014)... The report provides basic information on ... and industry overview. This report also presents product ... is separated by regions, technology and applications. The ... client survey, marketing channels, industry development trend and ...
Breaking Biology Technology:PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4SoundConnect Launches Leading Edge Business Communications Webinar Series 2SoundConnect Launches Leading Edge Business Communications Webinar Series 3Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2
... University researchers are finding ways to improve infrared photodetector ... systems, as well as used increasingly in commercial applications ... in a recent article in the journal ... how infrared photodetection can be done more effectively by ...
... LEXINGTON, Mass., Feb. 14, 2012 Avaxia Biologics, ... drugs that act locally within the gastrointestinal tract, ... million Series A angel-led financing.  Cherrystone Angels of ... from Beacon Angels, Boston Harbor Angels, Launchpad Venture ...
... PROVIDENCE, R.I., Feb. 14, 2012  Nabsys, Inc., a ... positional sequencing technology, today announced that data demonstrating ... DNA will be presented at the annual Advances ... 15 to 18, on Marco Island, Fla., and ...
Cached Biology Technology:New nano-material combinations produce leap in infrared technology 2New nano-material combinations produce leap in infrared technology 3Avaxia Biologics, Inc. Closes $4.1 Million Series A Financing to Advance Oral Antibodies for Inflammatory Bowel Disease 2Avaxia Biologics, Inc. Closes $4.1 Million Series A Financing to Advance Oral Antibodies for Inflammatory Bowel Disease 3Nabsys to Present DNA Sequence Data from Solid-State Nanodetectors at the Annual Advances in Genome Biology and Technology (AGBT) Meeting and the EMBL Omics and Personalized Health Conference 2Nabsys to Present DNA Sequence Data from Solid-State Nanodetectors at the Annual Advances in Genome Biology and Technology (AGBT) Meeting and the EMBL Omics and Personalized Health Conference 3
Anti-Kusabira Orange Monoclonal Antibody Description: 100 g Research Focus: tag Storage: -20C Shipping Temperature: 4C...
Anti-Kusabira Orange Monoclonal Antibody Description: 100 g Research Focus: tag Storage: -20C Shipping Temperature: 4C...
TXNL2 Antibody...
Rat polyclonal to Vitamin B3 ( Abpromise for all tested applications). Antigen: Chemical / Small Molecule, Vitamin B3 conjugated to BSA....
Biology Products: