Navigation Links
Researchers make progress in studying genetic traits of India-born populations

Despite the fact that the people of India constitute more than one-sixth of the world's entire population, they have been underrepresented in studies related to genetic diseases. And with the growth of modernization, complex genetic diseases associated with urban and western lifestyles have risen to near-epidemic proportions, making genetic cataloging and association studies of particular importance.

In response to this dearth of information, a team of researchers, including Pragna I. Patel, professor of biochemistry and molecular biology at the Keck School of Medicine of the University of Southern California (USC), and Noah Rosenberg, assistant professor in the department of Human Genetics at the University of Michigan, have conducted genetic analysis of India-born individuals in the U.S. Through their studies, they have begun to shed light on the genetic variations of the diverse population of India.

In a study to be published Dec. 22 online in the journal PLoS Genetics, a peer-reviewed journal published by the Public Library of Science (PLoS), Patel and colleagues analyzed 1,200 genome-wide polymorphisms collected from 432 individuals representing 15 different Indian populations.

This study represents the largest study of Indian genetic variation performed to date, in terms of the total number of sites in the human genome that were surveyed.

The researchers found that populations from India, and more generally, South Asia, make up one of the major human ancestry groups, with relatively little genetic differentiation among the Indian populations. Although the study used participants that may not reflect a random sample from India, these results still suggest that the frequencies of many genetic variants are distinctive in India compared to other parts of the world.

"We were struck both by the low level of diversity amongst people spanning such a large geographical region, and by the fact that people of the Ind ian sub-continent constituted a distinct group when compared to populations from other parts of the world," says Patel.

Her group is using this study as a foundation for future studies on the genetic basis of various common diseases in Asian Indians-such as heart disease, which is highly prevalent in this population. Individuals interested in participating in this study may see details at www.usc.edu/RICADIA.
'"/>

Source:University of Southern California


Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/15/2017)... ivWatch LLC , a medical device company focused on improving the ... its ISO 13485 Certification, the global standard for medical device quality ... ... device for the early detection of IV infiltrations. ... "This is an important milestone for ivWatch, as it validates ...
(Date:6/14/2017)... IBM ) is introducing several innovative partner startups at VivaTech ... startups and global businesses, taking place in Paris ... will showcase the solutions they have built with IBM Watson ... France is one of the most dynamic ... in the number of startups created between 2012 and 2015*, ...
(Date:5/6/2017)... -- RAM Group , Singaporean based technology ... biometric authentication based on a novel  quantum-state ... perform biometric authentication. These new sensors are based on a ... Group and its partners. This sensor will have widespread ... security. Ram Group is a next generation sensor ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... DuPont Pioneer ... that they have entered into a multiyear collaboration to identify and characterize novel ... additional tools for gene editing across all applications. , Under the terms of ...
(Date:10/12/2017)... ... 2017 , ... BioMedGPS announces expanded coverage of SmartTRAK Business ... US Hemostats & Sealants. , SmartTRAK’s US Market for Hemostats and Sealants module ... and biologic sealants used in surgical applications. BioMedGPS estimates the market will grow ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... launched Rosalind™, the first-ever genomics analysis platform specifically designed for life science ... in honor of pioneering researcher Rosalind Franklin, who made a major contribution ...
(Date:10/11/2017)... , ... October 11, 2017 , ... ... gene in its endogenous context, enabling overexpression experiments and avoiding the use of ... small RNA guides is transformative for performing systematic gain-of-function studies. , This ...
Breaking Biology Technology: