Navigation Links
Researchers make 'embryonic-like' stem cells from umbilical cord blood

A breakthrough in human stem cell research, producing embryonic-like cells from umbilical cord blood may substantially speed up the development of treatments for life-threatening illnesses, injuries and disabilities. The discovery made during a project undertaken with experts from the University of Texas Medical Branch and the Synthecon Corporation in the United States provides medical researchers and physicians with an ethical and reliable source of human stem cells for the first time.

The study, funded by the UK Government's Department of Trade and Industry, is led by Dr Colin McGuckin and Dr Nico Forraz from Kingston University's School of Life Sciences. It represents a significant step forward in the fast-developing field of stem cell research. Until now, experts have struggled to find a supply of cells in sufficient numbers that does not offend previous critics of stem cell research. The latest advance looks set to overcome such difficulties.

The trans-Atlantic team has been working with Drs Randall Urban, Larry Denner and Ronald Tilton from the University of Texas Medical Branch in Galveston. They have been using bioreactors at the Synthecon Corporation base in Houston enabling them to produce stem cells sharing many of the same characteristics as cells found in embryos. Research has so far relied on so-called adult cells found in blood and bone marrow from birth onwards or cells grown from embryos. The new type detected by the team harnesses the benefits of both. "We have found a unique group of cells that bring together the essential qualities of both types of stem cells for the first time," Dr McGuckin said.

The researchers findings may bring renewed hope to people awaiting treatment for a range of serious illnesses such as Diabetes, Alzheimer's Disease and multiple sclerosis. "Acquiring stem cells from embryos also has major limitations because it is difficult to obtain enough cells to transplant as well as getting the right tissue type for the patient," Dr McGuckin said. "Using cord blood gets over that obstacle because we can produce more stem cells and, with a global birth rate of 100 million babies a year, there is a better chance of getting the right tissue type for the many patients out there waiting for stem cell therapy. There is also far less likelihood of such cells being rejected when they are transplanted into people with liver disease, for example."

The team has taken its first steps towards proving its claims by growing defined liver tissue using the new cell type. By making use of special NASA-derived technology, the team is able to cultivate greater numbers of cells in equipment mimicking the effects of space microgravity. "Using Synthecon's bioreactors, originally designed by NASA, means the cells are able to expand faster, giving us a greater supply to work with," Dr Forraz said. "This system provides more cells for more tests, so we have the potential to make significant progress in applying the new cells to cure difficult to treat conditions such as juvenile diabetes, stroke, heart and liver disease."

Dr Urban who chairs UTMB's Internal Medicine department and serves as director of its Stark Diabetes Centre said he looked forward to the next phase of what was proving to be a fruitful collaboration. "We plan to use this technology to engineer pancreatic tissue as we work towards our goal of developing a cure for type 1 diabetes," he added.

The team's report will be published in the Cell Proliferation Journal on 18 August.


'"/>

Source:University of Texas Medical Branch at Galveston


Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/23/2017)... ITHACA, N.Y. , June 23, 2017  IBM ... in dairy research, today announced a new collaboration using ... the chances that the global milk supply is impacted ... project, Cornell University has become the newest academic institution ... Chain, a food safety initiative that includes IBM Research, ...
(Date:5/6/2017)... , May 5, 2017 ... just announced a new breakthrough in biometric authentication ... exploits quantum mechanical properties to perform biometric authentication. These ... smart semiconductor material created by Ram Group and ... finance, entertainment, transportation, supply chains and security. Ram ...
(Date:4/13/2017)... 2017 UBM,s Advanced Design and Manufacturing event ... emerging and evolving technology through its 3D Printing and ... alongside the expo portion of the event and feature ... focused on trending topics within 3D printing and smart ... event will take place June 13-15, 2017 at the Jacob ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... Bay, Florida (PRWEB) , ... October 11, 2017 ... ... and Drug Administration (FDA) has granted orphan drug designation to SBT-100, its novel ... (sdAb) for the treatment of osteosarcoma. SBT-100 is able to cross the cell ...
(Date:10/10/2017)... 10, 2017 International research firm Parks Associates announced ... at the TMA 2017 Annual Meeting , October 11 in ... residential home security market and how smart safety and security products impact ... Parks Associates: Smart Home ... "The residential security market has ...
(Date:10/9/2017)... ... ... The award-winning American Farmer television series will feature 3 Bar Biologics in ... 8:30aET on RFD-TV. , With global population estimates nearing ten billion people by ... feed a growing nation. At the same time, many of our valuable resources are ...
(Date:10/7/2017)... WA (PRWEB) , ... October ... ... industry leader in Hi-C-based genomic technologies, launched its ProxiMeta™ Hi-C metagenome deconvolution ... ProxiMeta Hi-C kit and accompanying cloud-based bioinformatics software to perform Hi-C metagenome ...
Breaking Biology Technology: