Navigation Links
Researchers identify gene involved in dog size

ics Branch. “Nearly all of what we learn from studying body structure, behavior and disease susceptibility in dogs helps us understand some aspect of human health and biology.?

In addition to Ostrander and her colleagues at NHGRI, the team included researchers from Cornell University in Ithaca, N.Y.; the University of Utah in Salt Lake City; the University of California, Los Angeles; the University of Southern California in Los Angeles; the University of Missouri in Columbia; the Waltham Centre for Pet Nutrition in Leicestershire, England; and the Nestle Research Center in St. Louis. Postdoctoral Fellow Nathan B. Sutter, Ph.D. from NHGRI’s Cancer Genetics Branch, served as lead author.

“By learning how genes control body size in dogs, we are apt to learn something about how skeletal body size is genetically programmed in humans. We also will increase our data set of genes likely to play a role in diseases such as cancer, in which regulation of cell growth has been lost,?said Ostrander, noting that the role of the IGF-1 gene family in prostate cancer susceptibility has already been well established.

Building upon previous research showing that the IGF-1 gene plays an important role in growth, body size and longevity in mice, the dog researchers used physical observations, X-ray imaging and DNA sequencing and genotyping analysis to study Portuguese water dogs—a breed that has an unusually wide range of skeletal size—as well as several small and large canine breeds. This analysis revealed that differences in dog body size appeared to be associated with minute genetic variations, referred to as single nucleotide polymorphisms (SNPs), in the IGF-1 gene. Researchers then narrowed the field of SNPs associated with small size by SNP genotyping in and around the IGF-1 gene in 463 Portuguese water dogs. A similar analysis was done using 526 dogs from 14 small breeds and nine giant dog breeds.

Ultimately, the researchers analyzed DNA fro
'"/>

Source:NIH/National Human Genome Research Institute


Page: 1 2 3 4

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers identify gene involved dog size

(Date:7/28/2014)... connections in prairie dogs have uncovered relationships that ... dog communities that may help limit the spread ... The work was done by researchers from North ... Center (NESCent). , "Prairie dogs are increasingly rare ... Jennifer Verdolin, lead author of a paper on ...
(Date:7/27/2014)... to date, researchers from the U.K. provide national, regional, ... virus (HCV). Findings published in Hepatology, a journal of ... indicate that genotype 1 is the most prevalent worldwide, ... reside in East Asia. Genotype 3, at just over ... by genotypes 2, 4, 6, and 5. , ...
(Date:7/27/2014)... scientists at Barts Cancer Institute have found that targeting ... significantly more effective, according to research published in ... Institute, part of Queen Mary University of London, have ... signals the body to repair itself after chemotherapy or ... the researchers removed FAK from blood vessels that grew ...
Breaking Biology News(10 mins):Social network research may boost prairie dog conservation efforts 2Hepatitis C virus genotype 1 is most prevalent worldwide 2New drug target can break down cancer's barrier against treatment 2
... (Cincinnati, OH) In a study published today in the ... an international team of researchers based in the U.S. and ... lethal, breath holding episodes associated with the neurological disease Rett ... that affects around 1 in 10,000 young girls. On October ...
... Institute in Boston have identified a new type of cell ... animal,s own cells from immune system attack. This ... drive lupus and other autoimmune diseases in which the immune ... The discovery, published in the September 16 issue of ...
... October 4, 2010 Onconova Therapeutics, Inc. announced ... regarding a Special Protocol Assessment (SPA) for the design ... 01910.Na) as monotherapy in patients with myelodysplastic syndromes (MDS), ... the bone marrow. The SPA provides FDA evaluation and ...
Cached Biology News:Research breakthrough hailed on the anniversary of gene discovery 2Discovery of a cell that suppresses the immune system 2Onconova announces FDA agreement of a SPA for a pivotal phase 3 trial of Estybon in MDS 2
(Date:7/29/2014)... South Carolina (PRWEB) July 29, 2014 DisasterTalk ... teams of people where cell phone masts or other transmitters ... up to 100 feet away without the need for any ... target longer ranges. , The new app has launched as ... US homes are at very high risk of being affected ...
(Date:7/29/2014)... 2014 Quorum Review IRB, the ... awarded accreditation by the International Association of ... Six Sigma Deployment Program. The citation recognizes robust ... , Quorum’s Lean Six Sigma program was evaluated ... designation. The designation is a public statement of ...
(Date:7/29/2014)... -- United Therapeutics Corporation (NASDAQ: UTHR ... the second quarter ended June 30, 2014. ... medicines are reaching increasing numbers of patients ... Martine Rothblatt, Ph.D., United Therapeutics, Chairman and ... quarter of our extended-release tablet called Orenitram ...
(Date:7/29/2014)... Bryan, TX (PRWEB) July 29, 2014 ... of autonomous modular cleanrooms, today announced a new leadership ... in the United States and abroad. , Maik ... named as the company’s President charged with leading the ... , “As we enter this stage of development and ...
Breaking Biology Technology:DisasterTalk App Could Save Lives as Report Reveals 8% of US Homes at Very High Risk of Natural Disaster 2Quorum Review IRB Accredited by IASSC for Lean Six Sigma Deployment Program 2Quorum Review IRB Accredited by IASSC for Lean Six Sigma Deployment Program 3United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 2United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 3United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 4United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 5United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 6United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 7United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 8United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 9United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 10United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 11United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 12United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 13G-CON Manufacturing, Inc. Announces Maik Jornitz as President 2
... Molecular Origami is ... help illustrate the basics of DNA origami, Harvard’s Wyss Institute has created a Flash-based interactive ... a DNA molecule and then allowing it to self assemble. , ... Boston, Mass. (PRWEB) January 28, 2010 -- Molecular ...
... world,s most powerful supercomputers, scientists at Lawrence Berkeley ... a good match for the future development of ... for green energy production because of their ability ... on "Franklin," a Cray XT4 massively parallel processing ...
... PRINCETON, N.J. , Jan. 27 Covance Inc. (NYSE: ... December 31, 2009 of $0.64 per diluted share.  For ... basis, inclusive of $0.10 per share in gains related to ... in the third quarter.  Excluding the gains on sales and the tax ...
Cached Biology Technology:Wyss Institute Launches "Molecular Origami" Interactive Feature 2Wyss Institute Launches "Molecular Origami" Interactive Feature 3Mismatched alloys are a good match for thermoelectrics 2Mismatched alloys are a good match for thermoelectrics 3Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 2Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 3Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 4Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 5Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 6Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 7Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 8Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 9Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 10Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 11Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 12Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 13Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 14Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 15Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 16Covance Reports Fourth Quarter Revenue of $485M and EPS of $0.64 Per Share 17
... 2D polyacrylamide gel electrophoresis (2D-PAGE) with biological ... core technology platform for proteomic analysis. 2D-PAGE ... samples limited only in the dynamic range ... proteins. Quantitative image based analysis of separated ...
... is ideal for high-fidelity amplification of ... as cloning and mutagenesis. High ... enzyme preparation containing recombinant DNA polymerase ... Site5' exonuclease) activity. Platinum Anti-Pfx ...
... PLAU N-term Antibody This antibody is generated ... synthetic peptide selected within aa 50~150 of ... in PBS with 0.09% (W/V) sodium azide. ... G column and eluted out with both ...
...
Biology Products: