Navigation Links
Researchers identify gene involved in dog size

ics Branch. “Nearly all of what we learn from studying body structure, behavior and disease susceptibility in dogs helps us understand some aspect of human health and biology.?

In addition to Ostrander and her colleagues at NHGRI, the team included researchers from Cornell University in Ithaca, N.Y.; the University of Utah in Salt Lake City; the University of California, Los Angeles; the University of Southern California in Los Angeles; the University of Missouri in Columbia; the Waltham Centre for Pet Nutrition in Leicestershire, England; and the Nestle Research Center in St. Louis. Postdoctoral Fellow Nathan B. Sutter, Ph.D. from NHGRI’s Cancer Genetics Branch, served as lead author.

“By learning how genes control body size in dogs, we are apt to learn something about how skeletal body size is genetically programmed in humans. We also will increase our data set of genes likely to play a role in diseases such as cancer, in which regulation of cell growth has been lost,?said Ostrander, noting that the role of the IGF-1 gene family in prostate cancer susceptibility has already been well established.

Building upon previous research showing that the IGF-1 gene plays an important role in growth, body size and longevity in mice, the dog researchers used physical observations, X-ray imaging and DNA sequencing and genotyping analysis to study Portuguese water dogs—a breed that has an unusually wide range of skeletal size—as well as several small and large canine breeds. This analysis revealed that differences in dog body size appeared to be associated with minute genetic variations, referred to as single nucleotide polymorphisms (SNPs), in the IGF-1 gene. Researchers then narrowed the field of SNPs associated with small size by SNP genotyping in and around the IGF-1 gene in 463 Portuguese water dogs. A similar analysis was done using 526 dogs from 14 small breeds and nine giant dog breeds.

Ultimately, the researchers analyzed DNA fro
'"/>

Source:NIH/National Human Genome Research Institute


Page: 1 2 3 4

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers identify gene involved dog size

(Date:8/21/2014)... pancreatitis involves the pancreas digesting itself resulting in severe ... the UK around 20,000 patients are diagnosed with the ... cure and treatment is restricted to intravenous fluid and ... Faculty of Life Sciences, who led the research, said ... from gall stones and excessive alcohol intake combined with ...
(Date:8/20/2014)... a study of 158 pregnant teenagers in Rochester, NY, ... intentional consumption of ice, cornstarch, vacuum dust, baby powder ... Cornell study. , Moreover, such teens had significantly lower ... eat nonfood substances. , Pregnant teens, regardless of pica, ... lead to iron deficiency and anemia. Low iron in ...
(Date:8/20/2014)... life can persist in a cold, dark world. A ... that examined waters and sediments from a shallow lake ... extreme environment supports microbial ecosystems. , The National ... has implications for life in other extreme environments, both ... are published in the current edition of the science ...
Breaking Biology News(10 mins):Insulin offers new hope for the treatment of acute pancreatitis 2Pica in pregnant teens linked to low iron 2University of Tennessee research uncovers subglacial life beneath Antarctic ice sheet 2
... Nature journal Leukemia suggests blocking part of ... leukemia resist treatment can increase the effectiveness of chemotherapy ... Medical Center report that their experimental combination treatment strategy ... was particularly effective at stopping a stubborn leukemia ...
... August 8, 2013 Research and ... addition of the "Fingerprint Biometrics - Global ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,This report ... in US$ Thousands by the following Product ...
... world full of hungry predators, prey animals must be constantly ... challenge when it comes to defending themselves. "One of ... they can,t run away," says John Orrock, a zoology professor ... necessarily hide, so what can you do? Some plants make ...
Cached Biology News:Study suggests way to fight therapy resistant leukemia by blocking DNA repair 2Study suggests way to fight therapy resistant leukemia by blocking DNA repair 3Fingerprint Biometrics: Automated FIS, and Non-AFIS - Global Strategic Business Report - 2013 2Eavesdropping plants prepare to be attacked 2
(Date:8/20/2014)... ear could improve the health of your heart, researchers ... Leeds used a standard TENS machine like those designed ... the tragus, the small raised flap at the front ... canal. , The stimulation changed the influence of the ... signals that can drive failing hearts too hard. , ...
(Date:8/19/2014)... Piscataway, NJ (PRWEB) August 20, 2014 ... engineering and regenerative medicine is an inadequate vascular ... engineered constructs and decellularized tissues is critical for ... Researchers have attempted to mitigate deficiencies in vascularization ... including adding scaffold bioactivity, optimizing scaffold design and ...
(Date:8/19/2014)... A Geisinger researcher on a personal crusade ... for Disease Control and Prevention (CDC) award recognizing his ... Joseph Boscarino , Ph.D. MPH, senior ... of researchers nominated for the Centers for Disease Control ... Data Methods and Study Design. "Hepatitis C ...
(Date:8/19/2014)... Robin Williams’ passing is a sad reminder ... individual. Symptoms range from slowness of voluntary movements ... severe depression. Parkinson’s disease progressively gets worse over ... neurons of the brain. As these patients struggle ... progressively gets worse, they look for options. ...
Breaking Biology Technology:'Tickling' your ear could be good for your heart 2Vascularization in Tissue Engineering Highlighted at 12th New Jersey Symposium on Biomaterials Science 2Geisinger investigator nominated for federal award 2Geisinger investigator nominated for federal award 3As We Mourn Robin Williams’ Passing, His Death Sheds Light on Patients Struggling with Parkinson’s Disease 2As We Mourn Robin Williams’ Passing, His Death Sheds Light on Patients Struggling with Parkinson’s Disease 3
... , , BRISBANE, Calif., Sept. 17 ... it will be collaborating with National Jewish Health(R)( )investigators in ... may play a role in idiopathic pulmonary fibrosis (IPF). InterMune ... from patients who participated in the Company,s Phase 3 clinical trials ...
... BETHESDA, Md., Sept. 16 American Capital Ltd. ... 15, it completed the sale of its portfolio company Axygen ... Inc., to Corning Incorporated for approximately $400 million. The ... fee income, from the equity invested by American Capital,s affiliated ...
... SAN MARINO, Calif., Sept. 16 Dr. M. Karen ... (Pink Sheets: VRAL), will address the 11th Annual SoCalBio Investor ... Custom Peptides on Chronic Inflammation," will take place mid-morning on ... The Loews Santa Monica Beach Hotel in Santa Monica, California. ...
Cached Biology Technology:InterMune Announces Collaboration With National Jewish Health on NIH-Supported Genetic Research in Idiopathic Pulmonary Fibrosis 2InterMune Announces Collaboration With National Jewish Health on NIH-Supported Genetic Research in Idiopathic Pulmonary Fibrosis 3American Capital Receives $182 Million In Proceeds From Sale of Axygen Bioscience 2American Capital Receives $182 Million In Proceeds From Sale of Axygen Bioscience 3American Capital Receives $182 Million In Proceeds From Sale of Axygen Bioscience 4Viral Genetics' Lead Scientist Dr. M. Karen Newell Will Present at 11th Annual SoCalBio Investor and Partnership Conference 2
Mouse monoclonal [6G11] to Cytohesin 1 + 2 ( Abpromise for all tested applications)....
HP 1 alpha Immunogen: Synthetic peptide between amino acids 1-100 of the human HP 1 alpha protein. Storage: -20 C, Avoid Freeze/Thaw Cycles...
... KLH-conjugated, synthetic peptide corresponding ... of mouse p19ARF. The ... acids 62-75. Clone 5-C3-1. ... by immunoblot. Stability ...
Request Info...
Biology Products: