Navigation Links
Researchers from the UGR use a bacterium to obtain biopreservatives from food

egies to compete for nutrients in their environment. One of these strategies is to produce antimicrobial compounds such as antibiotics, certain metabolism products, lytic agents, numerous types of protein exotoxins, and bacteriocins. It has become increasingly more necessary to find new antimicrobial agents because of the stronger resistance acquired by bacteria. Researcher Sánchez Hidalgo points out that natural antimicrobial cationic peptides such as bacteriocins "represent a good alternative."

Bacteriocins are proteins that are biologically active against members of the same species or species closely related to the producing bacterium. Some noteworthy bacteriocins those produced by lactic-acid bacteria (LAB), as they have been used to prepare fermented food, improve quality, and extend the average duration of many foods for centuries.

The work presented in the doctoral thesis approaches the molecular aspects of the permeabilization that AS-48 exerts on bacterial membranes. "We designed a strategy to carry out site-directed mutagenesis on the as-48A gene, the one which generates enterocin AS-48", the researcher from Granada pointed out, "and we have studied the role of seven amino acids that could be involved in biological activity and in the hydrophobic nature and thermodynamic stability of the molecule. We made this study by changing the amino acids into others with different properties."

The results of this work made it possible to conclude that while some of the mutated amino acids are essential for biological activity, others improve AS-48 biotechnological characteristics. During the process of obtaining mutated amino acids, it was also determined that three out of the ten genes involved in the production of AS-48 express themselves together. The research also determined the way of that these genes are regulated and expressed as well.


'"/>

Source:Universidad de Granada


Page: 1 2

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
(Date:8/10/2015)... Germany , August 10, 2015 ... leader in Eye Tracking Technology for more than two ... Tracking Platform for integration into all consumer display formats. ... for seamless integration of eye tracking into consumer tablets, ... augmented reality smart glasses. Omnivision,s leading sensor technology contributes ...
(Date:8/5/2015)... 5, 2015 According to a ... Market by Software, Services, Vertical (BFSI, Airport, IT & Telecom, ... Global Forecast to 2020", published by MarketsandMarkets, defines and ... into various segments. The global PIAM Market is estimated ... Million by 2019, at a CAGR of 14.9 % ...
(Date:8/3/2015)... Aug. 3, 2015 Synaptics, Inc. (Nasdaq: ... today announced that members of the executive management team ... Crest Global Technology Leadership Forum on Tuesday, August 11, ... be held at the Sonnenalp Resort in ... may include forward-looking information. An audio webcast of the ...
Breaking Biology News(10 mins):SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 2Physical Identity and Access Management Market Worth $546.2 Million by 2019 3Physical Identity and Access Management Market Worth $546.2 Million by 2019 4
... expects to fund some 240 top researchers in its ... of grantees follows the 299 researchers who received grants ... In total, 2503 proposals were submitted to the second ... is studying the kidney glomerular ultrafiltration in both health ...
... for Microbiology (ASM) today announced plans to launch mBio ... microbiology research broadly accessible, in mid-2010. The focus of ... spanning the entire spectrum of microbiology and related fields. ... interconnected one in which microbes interact with living and nonliving ...
... circumpolar Arctic research focuses on the physical, direct changes ... and temperature increases. "What,s understudied is the living component ... "Donie" Bret-Harte, associate professor of biology at the University ... be published September 11, 2009 in the journal ...
Cached Biology News:ERC Starting Grant for the researcher of kidney diseases 2American Society for Microbiology to launch new open-access journal 2Scientists seek new emphases in Arctic climate change research 2
(Date:9/2/2015)... ... September 02, 2015 , ... ... compliance, quality systems, analytical testing, education and consulting services for the medical ... medical device products/processes development, design control, validation, quality assurance and regulatory compliance. ...
(Date:9/2/2015)... 02, 2015 Research ... addition of Jain PharmaBiotech,s new report "Biochips ... to their offering. This report is ... and applications. The report starts with a description ... markets. Technologies include array comparative genomic hybridization (CGH), ...
(Date:9/2/2015)... Sep. 02, 2015 ... the addition of Jain PharmaBiotech,s new report ... their offering. This report follows the ... that can be objectively measured and evaluated as ... as well as pharmacological responses to a therapeutic ...
(Date:9/2/2015)... 02, 2015 ... announced the addition of Jain PharmaBiotech,s new ... Companies" to their offering. ... besides fluorescence in situ hybridization (FISH), comparative ... cytogenetics includes application of nanobiotechnology, microarrays, real-time ...
Breaking Biology Technology:NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 2NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 3NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 4NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 5NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 6NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 7Global Biochips and Microarrays Technologies, Markets and Companies Report 2015 with Market Size in 2014 and Projected Value for the Years 2019 and 2024 2Updated 2015 Biomarkers Report - Latest Technologies, Markets and Companies Insights to 2024 with over 1,000 References 2Updated 2015 Biomarkers Report - Latest Technologies, Markets and Companies Insights to 2024 with over 1,000 References 3Global Cytogenetics Technologies Study 2015-2025 - Latest Markets and Companies Analysis 2Global Cytogenetics Technologies Study 2015-2025 - Latest Markets and Companies Analysis 3
... featured in oral presentation ... TSX Exchange Symbol: ... is pleased to announce that tomorrow it is making,an oral ... at the International Atherosclerosis Society (IAS),Workshop on HDL. The presentation ...
... A hybrid device combining force and fluorescence developed ... possible the accurate detection of nanometer-scale motion of biomolecules ... energy transfer and an optical trap, we now have ... a biomolecule at an extremely low applied force, said ...
... IRVINE, California, October 11 IsoTis, Inc.,(NASDAQ: ISOT ... adjourned the special meeting of stockholders it called to ... IART ) ("Integra") pursuant to an agreement and ... The special meeting of stockholders was held at 9 ...
Cached Biology Technology:Resverlogix is Presenting at IAS HDL Workshop 2New force-fluorescence device measures motion previously undetectable 2New force-fluorescence device measures motion previously undetectable 3IsoTis Adjourns Special Meeting to October 23, 2007 2IsoTis Adjourns Special Meeting to October 23, 2007 3IsoTis Adjourns Special Meeting to October 23, 2007 4
... designed to rapidly and reliably amplify ... patented APA Technology. APAgene provides hassle-free, ... competitive price. All necessary ingredients are ... Kit can be used for identifying ...
A set of five peptides which can be used to calibrate a Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) or Electrospray Ionization (ESI) mass spectrometer....
... the only PCR system that ensures successful ... It provides accuracy, consistency, and dependability for ... property of the DNA templates. This system ... unique blend of thermostable enzymes that is ...
ID clarifier: With ethidium bromide (50 μg/ml)...
Biology Products: