Navigation Links
Researchers find missing genes of ancient organism

Yale scientists report in the journal Nature that the "missing" genes for tRNA in an ancient parasite are made up by splicing together sequences in distant parts of the DNA genome.

The research led by Professor Dieter Söll in the Department of Molecular Biophysics and Biochemistry at Yale focuses on the most ancient organism with a known genome sequence. Nanoarchaeum equitans, is a member of a new phylogenetic kingdom in the Archaea containing organisms that are primitive, parasitic and extremophile, or notable for living in the most extreme environments.

Surprisingly, Söll's team found that, although the genome of Nanoarchaeum lacks several intact tRNA genes, functional forms of those tRNAs can be made by copying from two distant DNA sequences -- and joining them.

The regions on the separate pieces, that allow them to find each other and splice, are somewhat similar to internal sequences found in tRNA genes of more complex organisms., These regions, termed introns, are sequences that are cut out of whole gene transcripts during the process of tRNA maturation. The known tRNA introns in organisms like yeast, however, appear to have no function. Therefore, modern tRNA introns might be remnants of an old essential process of tRNA biosynthesis.

"These results may point to extremophiles in the kingdom of Archaea as predecessors of more modern organisms that have gained a genetic load in the process of evolution," said Söll. "Or they may represent a specialization that has rid itself of genetic baggage to exist in extreme environments."

Understanding how primitive organisms like Nanoarchaea operate gives clues to -- but not proof of -- the relationship between modern and ancient organisms.

###

Other authors on the paper include Lennart Randau and Michael J. Hohn from Yale, and Richard Münch and Dieter Jahn from the Technical University Braunschweig, Germany. This work was supported by grants from the National Institut
'"/>

Source:Yale University


Page: 1 2

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers trace evolution to relatively simple genetic changes
8. Researchers add new tool to tumor-treatment arsenal
9. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
10. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
11. Researchers develop rapid diagnostic tool for pathogen identification
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers find missing genes ancient organism

(Date:8/28/2014)... 28, 2014) Researchers at the University of Minnesota ... dystrophy (FSHD) to be used for muscle regeneration research ... therapies for FSHD. , The research is published in ... . , There is no treatment for FSHD, which ... type of muscular dystrophy. FSHD is an unusual genetic ...
(Date:8/28/2014)... compounds that could positively impact the global ... possible, thanks to researchers in Penn State,s ... suppository made from the seaweed-derived food ingredient ... Tenofovir provides a woman-initiated, drug-delivery vehicle that ... transmitted infections during unprotected heterosexual intercourse, the ...
(Date:8/28/2014)... roads will be built worldwide by 2050. Many of ... they bring an influx of destructive loggers, hunters and ... created a ,global roadmap, for prioritising road building across ... of development and environmental protection. , The map has ... importance of ecosystems and a ,road-benefits, layer that estimates ...
Breaking Biology News(10 mins):UMN researchers find animal model for understudied type of muscular dystrophy 2Sensory-tested drug-delivery vehicle could limit spread of HIV, AIDS 2Sensory-tested drug-delivery vehicle could limit spread of HIV, AIDS 3Study shows where on the planet new roads should and should not go 2Study shows where on the planet new roads should and should not go 3
... of Post-Traumatic Stress Disorder (PTSD) is unpredictable. Because it ... is difficult to identify preventative or causative factors. Scientists ... to study the disorder, but that means they can,t ... trauma. Now, through a combination of genetic ...
... 13, 2013) For consumers of the typical Western dietladen with ... to believe that there is such a thing as an ... Charles Zuker, PhD, and colleagues at Columbia University Medical Center ... (think seawater levels, not potato chips), the first step in ...
... 13, 2013) Whitehead Institute researchers have identified a ... for the generation of undesirable white fat cells. When ... to accumulate lipid droplets or mature from their precursors. ... iswhat it takes to make fat cells," says Whitehead ...
Cached Biology News:Gene associated with high anxiety can have protective effect on the battlefield 2Gene associated with high anxiety can have protective effect on the battlefield 3Scientists discover how animals taste, and avoid, high salt concentrations 2Scientists discover how animals taste, and avoid, high salt concentrations 3Long noncoding RNAs control development of fat cells 2
(Date:8/28/2014)... 28, 2014 Earlier this month, ... in partnership with the U.S. Air Force on the ... results indicated that this type of fuel made from ... will be important to America’s Eco friendly future. In ... a mandate to become independent of foreign oil over ...
(Date:8/28/2014)... 28, 2014 Whitehouse Laboratories is excited ... partnership with PTI Inspection Systems that will ... of the art leak testing method development and validation ... currently available. As part of this agreement, Whitehouse Labs ... Leak Detection Instrument developed and manufactured by PTI. ...
(Date:8/27/2014)... Rhythm, a biopharmaceutical company developing peptide therapeutics ... in metabolic disorders, announced today that it has filed ... Securities and Exchange Commission (SEC) relating to the proposed ... The number of shares to be offered and the ... determined. Citigroup and Cowen and Company will ...
(Date:8/27/2014)... 27, 2014   MSC , a healthcare performance ... announced the appointment of Mary Beth Loesch ... years of experience preparing companies for rapid growth and ... Vice President of Corporate Development and Healthcare. In that ... , as well as corporate strategy and marketing. Previously, ...
Breaking Biology Technology:Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 2Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 3Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 4Can Small Farmers and a New Seed Based Biofuel “Green” the World? Major Universities and Even the U.S. Air Force Seem to Think So 5Whitehouse Labs Renews Partnership with PTI Inspection Systems 2Whitehouse Labs Renews Partnership with PTI Inspection Systems 3Rhythm Files Registration Statement for Proposed Initial Public Offering 2MSC names Mary Beth Loesch President and CEO 2
... ANGELES, Feb. 18 The Board of Directors wishes to ... 2009 it resolved to file a Form 15 with effect ... the approval of stockholders but in the interests of keeping ... Release.The effect of this filing is to release the company ...
... SAN DIEGO, Feb. 18 Zogenix, Inc. ("Zogenix"), a ... Drug,Administration (FDA) has provided a target date of July ... for Sumavel DosePro (sumatriptan,injection) needle-free delivery system. Zogenix ... treatment of migraine attacks with or without,aura, and the ...
... Inc. (the "Company") (Nasdaq: PDGI ), a ... biotechnology, generic drug and medical device companies, today announced ... Brazil to further enhance its Latin American presence.PharmaNet has ... 2002 with a network of field-based staff in Brazil, ...
Cached Biology Technology:EESTECH Inc - Release From SEC Filing 2EESTECH Inc - Release From SEC Filing 3EESTECH Inc - Release From SEC Filing 4Zogenix Reports FDA Provides New PDUFA Date for Sumavel(TM) DosePro(TM) 2PharmaNet Development Group, Inc. Expands Latin America Operations with Opening of Brazil Office 2PharmaNet Development Group, Inc. Expands Latin America Operations with Opening of Brazil Office 3PharmaNet Development Group, Inc. Expands Latin America Operations with Opening of Brazil Office 4PharmaNet Development Group, Inc. Expands Latin America Operations with Opening of Brazil Office 5
... different human fetal normal tissues are ... upon request. Customers can choose ... set, and pay 70% of the ... P Set products are for research ...
... delivery of buffer and fixative results ... version. In Vivo Manual Perfusion Fixation ... of buffer and fixative results in ... use and clean--Complete system with everything ...
Mouse IL-31 RA Biotinylated Affinity Purified PAb...
... plus assay system offers the ... Designed for batch-processing systems, Long ... density microplates such as 384-well ... Convenient storage conditions ( 2 ...
Biology Products: