Navigation Links
Researchers find how some antibiotics kill bacteria

polymerase's molecular 'hood' we couldn't see what the problem was," she said. "We never suspected that removing this ion was what killed rifamycin-sensitive bacteria. But the resolution of previous atomic structures wasn't sufficient enough to see that."

The higher-resolution images also showed that rifapentin and rifabutin each bind just a little differently to E. coli, but still bring about the same results.

The answer to creating a new breed of bacteria-resistant antibiotics may lie in these variations in binding.

"From these findings we can suggest how rifamycins that are currently used in therapy can be improved to be effective even against existing resistant strains of bacteria," Artsimovitch said

Rifamycins are what drug companies call "broad-spectrum antibiotics." Not only are they effective against tuberculosis, they also act against a variety of other pathogens including Neisseria meningitidis, the bacterium that causes one form of meningitis; Helicobacter pylori, which causes stomach ulcers; and even some parasitic worms by eliminating the symbiotic bacteria parasites depend on.

"It's the kind of drug the pharmaceutical business wants to produce," Artsimovitch said. "They're looking for the broadest range of antibiotics possible. Rifamycins would be ideal drugs if we could figure out how to get rid of resistance."


'"/>

Source:Ohio State University


Page: 1 2 3

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers find how some antibiotics kill bacteria

(Date:9/30/2014)... , Sept. 30, 2014  Spectra Automation, ... for the biotech and power generation industries, ... RECONN Bioprocess Manager, an easy-to-use and cost-effective ... towards bioprocess development laboratories. ... bioreactor and analyzer systems. Accessing and consolidating ...
(Date:9/30/2014)... -- Winners of The Economist,s prestigious Innovation awards 2014 ... place at the JW Marriott Hong Kong on Friday, October 10 ... their experiences and the lessons those hold for others. The awards, ... the past decade, will be presented at a ceremony in ... will be the first time the ceremony has come to ...
(Date:9/29/2014)... Plants have a symbiotic relationship with certain bacteria. ... and defend against invaders an important step ... Now, scientist have discovered that plants may package ... that sprouting plants are colonized from the beginning. ... presented their findings today at the 5th ASM ...
Breaking Biology News(10 mins):Spectra Automation Introduces RECONN Bioprocess Manager 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 2Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 3Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 4Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 5Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 6Hear from The Economist's 2014 Innovation Award Winners at Innovation Summit on October 10th in Hong Kong 7Plants prepackage beneficial microbes in their seeds 2
... Researchers have found that patients with multiple sclerosis (MS) ... Epstein-Barr virus. The virus, which causes mononucleosis and may ... play a role in MS. However, the mechanism linking ... , Scientists think that MS--which can cause vision problems, ...
... St. Jude Children's Research Hospital have discovered that a protein ... molecule that is key to the ability of red blood ... toxins, and of cells to extract energy from nutrients. ... within the outer membrane of the cell's energy powerhouse ...
... Center has opened a new clinical study using a ... glioblastoma multiforme, a largely untreatable brain tumor. This ... in patients using measles to kill cancer. , "We ... the most lethal cancers," says Eva Galanis, M.D., oncologist ...
Cached Biology News:Epstein-Barr virus might kick-start multiple sclerosis 2Epstein-Barr virus might kick-start multiple sclerosis 3Epstein-Barr virus might kick-start multiple sclerosis 4ABCB6 is key to production of heme in hemoglobin 2Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer 2Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer 3
(Date:10/1/2014)... 2014 METTLER TOLEDO’s newly improved XS ... balances as well as a dual range ... the new SmartPan™ weighing pan delivers results up to ... all balances, ergonomic design details mean users no longer ... for long periods in front of the balance. Barbara ...
(Date:10/1/2014)... 01, 2014 Weighing applications in ... the final product. However, while the pharmaceutical industry ... such as Good Manufacturing Practices (GMP) usually provide ... the manufacturer to interpret these guidelines and assess ... quality. METTLER TOLEDO experts have created a new ...
(Date:10/1/2014)... As the world takes its first steps into the ... century would mark the beginning of a new era of ... fact that the world is experiencing a rapid rise in ... Almost half of these chronic conditions are due to lifestyle ... care and intervention. While the world is experiencing a rapid ...
(Date:10/1/2014)... 2014 In response to its ... address sales, training and consumer engagement challenges, ... mobile applications to turn their clients’ visions into ... customized mobile app creations, are now featured on ... partnership with Toyota, StudioPMG created a robust cross-platform ...
Breaking Biology Technology:METTLER TOLEDO’s XS Balance Line Delivers Performance and Ergonomics To Safeguard Health in the Workplace 2METTLER TOLEDO’s XS Balance Line Delivers Performance and Ergonomics To Safeguard Health in the Workplace 3Comply with Weighing-Related Regulations in Pharma Manufacturing 2Fighting Mortality and Morbidity of Chronic Health Disorders during Open Access Week 2Fighting Mortality and Morbidity of Chronic Health Disorders during Open Access Week 3Digital Agency Studio PMG Launches New Case Studies on Website 2
... , , , There is obviously no single , ... amplifications. For example, , depending on the length and sequence ... can differ from each other. Finding the optimal or the , ... and efficient amplification of a specific target. , ...
... Using Eppendorf Mastercycler gradient , , , , ... NPC Laboratory, Institute of Postgraduate Studies and Research, University , of Malaya, Kuala Lumpur, Malaysia , , ... , , ... , , ...
... Plant RNA, Using the Eppendorf Perfect ... , , , Sonja Vorwerk and ... Zchtungsforschung, Carl-von-Linn , Weg 10, 50829 Cologne, Germany , ... , Barbro Patterson, Eppendorf AG, Germany , ...
Cached Biology Technology:PCR Optimization 2PCR Optimization 3Amplification of Epstein-Barr Virus Exon C with Difficult Primers , Using Eppendorf Mastercycler gradient 2Amplification of Epstein-Barr Virus Exon C with Difficult Primers , Using Eppendorf Mastercycler gradient 3Amplification of Epstein-Barr Virus Exon C with Difficult Primers , Using Eppendorf Mastercycler gradient 4Amplification of Epstein-Barr Virus Exon C with Difficult Primers , Using Eppendorf Mastercycler gradient 5Simple and Rapid Isolation of Plant RNA, Using the Eppendorf Perfect RNA, Eukaryotic, Maxi Kit 2Simple and Rapid Isolation of Plant RNA, Using the Eppendorf Perfect RNA, Eukaryotic, Maxi Kit 3Simple and Rapid Isolation of Plant RNA, Using the Eppendorf Perfect RNA, Eukaryotic, Maxi Kit 4Simple and Rapid Isolation of Plant RNA, Using the Eppendorf Perfect RNA, Eukaryotic, Maxi Kit 5Simple and Rapid Isolation of Plant RNA, Using the Eppendorf Perfect RNA, Eukaryotic, Maxi Kit 6
... Cy3 Ab Labeling Kit, 1 kit. ... with CyDye fluorescent dyes. Conjugations are ... complete within 1 h. Dyes are ... to ensure consistent labelings. Category: Blotting ...
Recombinant Human Erythropoietin (Tissue Culture Grade)...
Human PDGF R beta MAb (Clone # PR7212)...
Rabbit Serum New Zealand or California Origin...
Biology Products: