Navigation Links
Researchers find how some antibiotics kill bacteria

polymerase's molecular 'hood' we couldn't see what the problem was," she said. "We never suspected that removing this ion was what killed rifamycin-sensitive bacteria. But the resolution of previous atomic structures wasn't sufficient enough to see that."

The higher-resolution images also showed that rifapentin and rifabutin each bind just a little differently to E. coli, but still bring about the same results.

The answer to creating a new breed of bacteria-resistant antibiotics may lie in these variations in binding.

"From these findings we can suggest how rifamycins that are currently used in therapy can be improved to be effective even against existing resistant strains of bacteria," Artsimovitch said

Rifamycins are what drug companies call "broad-spectrum antibiotics." Not only are they effective against tuberculosis, they also act against a variety of other pathogens including Neisseria meningitidis, the bacterium that causes one form of meningitis; Helicobacter pylori, which causes stomach ulcers; and even some parasitic worms by eliminating the symbiotic bacteria parasites depend on.

"It's the kind of drug the pharmaceutical business wants to produce," Artsimovitch said. "They're looking for the broadest range of antibiotics possible. Rifamycins would be ideal drugs if we could figure out how to get rid of resistance."


'"/>

Source:Ohio State University


Page: 1 2 3

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers find how some antibiotics kill bacteria

(Date:12/10/2014)... N.C. , Dec. 9, 2014  Valencell, a ... it is seeing a staggering demand from its licensees ... the Company revealed, is not solely coming from fitness ... as well. "A wearable is only as ... result, accuracy is the ultimate driver in long-term mass ...
(Date:12/10/2014)... SAN DIEGO , Dec. 9, 2014 ... and collaboration catalyst that provides the connective tissue that ... by enabling them to easily share client-level information; earned ... Foundation to expand to organizations serving seniors aging in ... San Diego" partner on December 11 th 4-6p. ...
(Date:12/10/2014)... 2014     ...   Jifflenow, a leading ... for business-to-business (B2B) events, today announced a partnership ... near-field communication (NFC), Bluetooth low energy (BLE), and ... , Jifflenow will integrate its meeting ...
Breaking Biology News(10 mins):Wearable Technology Products Demand Highly Accurate Biometric Technology 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 2Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 3Community Information Exchange San Diego Launches Pilot, Secures $1 Million Expansion Grant, and Becomes a "Live Well San Diego" Partner 4Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3
... STANFORD, Calif. Globs of human fat removed ... and easily coaxed to become induced pluripotent stem cells, ... often used by researchers, according to a new study ... natural resource," said Stanford surgery professor and co-author of ...
... strains capable of neutralizing toxins produced by blue-green ... Gordon,s University, Aberdeen. Aakash Welgama presented the group,s ... at Heriot-Watt University, Edinburgh. Blooms of blue ... and salt water throughout the world. They produce ...
... genes associated with Alzheimer,s disease, while French colleagues uncovered ... genome-wide association study (GWAS) involving 16,000 individuals, are published ... new genes found to be associated with the common ... Research Trust spoke of "a leap forward for dementia ...
Cached Biology News:'Liposuction leftovers' easily converted to IPS cells, Stanford study shows 2'Liposuction leftovers' easily converted to IPS cells, Stanford study shows 3Largest ever Alzheimer's genome study unveils dementia mysteries 2Largest ever Alzheimer's genome study unveils dementia mysteries 3
(Date:12/24/2014)... (PRWEB) December 23, 2014 GMO corn ... biotechnology company, Syngenta, are in the process of being ... The consolidated case is In Re: Syngenta AG MIR ... District Court for the District of Kansas. , Management ... been handed over to U.S. District Judge John W. ...
(Date:12/24/2014)... December 23, 2014 The ... such as its definition, classification, application and ... specification, manufacturing process, and product cost structure. ... applications. The analysis also covers upstream raw ... industry development trend and proposals. In the ...
(Date:12/24/2014)... 2014 Vermillion, Inc. (Nasdaq:   VRML), ... announced today that investors including Oracle Investment Management, ... and several Vermillion directors have agreed to purchase ... common stock and warrants to purchase unregistered shares ... Under the terms of the ...
(Date:12/22/2014)... December 22, 2014 The Center ... leader of technical training across the life sciences industry, ... Management (SCDM) to provide the organization's members with ... —providing access to the more than 350 sessions across ... with 10% off when registering for a public ...
Breaking Biology Technology:Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2Worldwide Methyl Mercaptan Market 2015-2020 Forecasts on Development & Trends Now Available at ReportsnReports.com 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 2Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 3Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 4Vermillion Announces Equity Financing of up to $18.9 Million; Suspends ATM Program 5CfPIE Announces Partnership with the Society for Clinical Data Management 2CfPIE Announces Partnership with the Society for Clinical Data Management 3
... BioMarin,Pharmaceutical Inc. (Nasdaq and SWX: BMRN) announced ... Daiichi Sankyo), has received marketing,approval from the Japanese ... label extension of Biopten(R) (sapropterin dihydrochloride), which,contains the ... for the,treatment of patients with phenylketonuria (PKU). BioMarin ...
... Federal Court Enters Consent Judgment Terminating Litigation --, ... WYE ) and,Impax Laboratories Inc. today announced ... patent infringement litigation pertaining to Impax,s proposed,generic capsule ... by the United States District Court for the ...
... July 16 /PRNewswire/ - Eugene Melnyk and EM ... a number of incomplete or,inaccurate statements in Biovail ... hallmark of this proxy contest to date has ... the Board and management using the,same tactics," stated ...
Cached Biology Technology:Biopten (Sapropterin Dihydrochloride) Approved by Japanese Ministry of Health for the Treatment of PKU 2Biopten (Sapropterin Dihydrochloride) Approved by Japanese Ministry of Health for the Treatment of PKU 3Biopten (Sapropterin Dihydrochloride) Approved by Japanese Ministry of Health for the Treatment of PKU 4Wyeth and Impax Announce Final Settlement of Effexor XR Patent Suit 2Wyeth and Impax Announce Final Settlement of Effexor XR Patent Suit 3
... These 2800mL wide mouth PYREX Fernbach-style culture ... center of the flask bottom to achieve ... triple baffled flasks have a Delong-style 38mm ... steel closures. For plastic closures see Nos. ...
... The loxP-PGK-gb2-neo-loxP template is designed ... and eukaryotic cells. The loxP-PGK-gb2-neo-loxP ... which combines a prokaryotic promoter (gb2) ... E.coli with a eukaryotic promoter (PGK) ...
These are replacement caps for No. CLS6980 5mm PYREX NMR tubes. Proper method to remove caps is to slice them from the tube. Caps come in eight assorted/mixed colors. Packed in bags of 100....
... CLS number is a new ... match Cornings product number. If ... order under the old Sigma-Aldrich ... service for assistance. ID clarifier: ...
Biology Products: