Researchers discover new gene responsible for brittle bone disease ( with recessive forms accounting for re...)

Researchers discover new gene responsible for brittle bone disease

with recessive forms accounting for recurrence. When each parent has one mutated gene and one normal gene, they have one-in-four chance of having a child with osteogenesis imperfecta.

Funding for the research came from the National Institutes of Health, the Baylor College of Medicine Developmental Disabilities Research Center, and the Shriners of North America. Others institutes participating were the Istituto Nazionale per la Ricerca sul Cancro in Genova, Italy, The Shriners Hospital for Children in Oregon, McGill University in Montreal and The University of Washington in Seattle.

"Beyond OI, there may be other connective tissue disorders caused by mutations in genes associated with 3-prolyl hydroxylation, a process that occurs in many types of tissues," Boyce said. "Current treatment for OI does not cure the disease and is designed to reduce the risk of fracture. Only through a better understanding of the disease at the genetic and protein level will we be able to someday offer something better."
'"/>

Source:University of Rochester Medical Center

Page: 1 2 3
Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain

Post Your Comments:

(Date:11/25/2009)...e course of a lifetime, the heart pumps some 250 m...der to do this, the muscle fibers of the heart hav...ed by Dr. Wolfgang Rottbauer, vice chair of the De...Hospital (Chairman: Prof. Dr. H. A. Katus), has di...bility of the smallest muscular unit, the sarcomer...

(Date:11/24/2009)...science is opening new doors to understanding how ... hearing of a marine mammal or if they hear it at...X-ray scanners that NASA uses to detect flaws in t...now allowing scientists to peek inside the giant h...hree-dimensional replicas of a whale,s hearing ana...

(Date:11/24/2009)... NEW YORK (November 24, 2009) -- The Wildl...eport revealing that the last remaining population...tly due to the rising tide of poaching and habitat...lp inform Russian officials of what needs to be do... biggest cat. , The report was rele...

[1] New genetic cause of cardiac failure discovered [1] Rocket science leads to new whale discovery [1] Report shows dramatic decline in Siberian tigers

...environmental conditions in the Canadian Rockies a...he region, say University of Alberta researchers. ...y the result of human activities--are diminishing ... that could lead to the butterflies being less abl...cientist at the University of Alberta and an autho...

... that advances our ability to discern the ancient ... and their biological functions, researchers have ... single gene duplication that occurred over a hund...nts. The work is reported in Current Biology by a ...eds, England. , Gene duplication--a relatively unc...

...mediate wake of Hurricane Katrina, scientists and ...ther to generate information on the contaminated f...erts and public health officials. , In a matter of... Hill,s Marine Sciences Program and Renaissance Co...nal Center for Supercomputing Applications (NCSA),...

Other Biology News:Expanding forests darken the outlook for butterflies, study shows 2 Analysis of flower genes reveals the fate of an ancient gene duplication 2 UNC computer, marine scientists collaborate to predict flow of toxic waters from Katrina 2 UNC computer, marine scientists collaborate to predict flow of toxic waters from Katrina 3

Expanding forests darken the outlook for butterflies, study shows Analysis of flower genes reveals the fate of an ancient gene duplication UNC computer, marine scientists collaborate to predict flow of toxic waters from Katrina

(Date:11/25/2009)...Nov. 25 /PRNewswire-Asia/ -- Sinovac Biotech Ltd. ...es, announced today that it executed,a joint ventu...ccine,Technology Co., Ltd. (Sinovac Dalian). The J...e human-use vaccines. Sinovac will contribute its ...ializing world-class vaccines; the,other party wil...

(Date:11/25/2009)... Ardea Biosciences, Inc. ...rt, Pharm.D., president and chief executive office...ealth Care Conference. , ,Presentation details ar...re Conference,Date: Tuesday, December 1, 2009...New York Palace Hotel, New York, NY,Webcast: <a...

(Date:11/24/2009)... IES (Nasdaq: IESC ), a...nications systems and services for the commercial,...ay that its commercial business group has been awa...l the electrical systems for the Level 4 bio-safet...y Medical Research Institute of Infectious Disease...

(Date:11/24/2009)...w York investment bank KTA Capital,s client Neuren...7 mil convertible note private placement with a U....as arranged by KTA Capital as Neuren,s exclusive p... New York (PRWEB) November 23, 2009 -- The ind... ("KTA Capital") has announced that its ...

Breaking Biology Technology:Sinovac Establishes Joint Venture to Expand Human-Use Vaccine Development and Manufacturing Capabilities 2 Sinovac Establishes Joint Venture to Expand Human-Use Vaccine Development and Manufacturing Capabilities 3 Ardea Biosciences to Present at the Piper Jaffray 21st Annual Health Care Conference 2 Integrated Electrical Services Awarded Contract to Provide Electrical Systems for U.S. Army Medical Research Institute of Infectious Diseases 2 KTA Capital Arranges an AU$6.7 Million Private Placement by Neuren Pharmaceuticals 2

[0] Sinovac Establishes Joint Venture to Expand Human-Use Vaccine Development and Manufacturing Capabilities [0] Ardea Biosciences to Present at the Piper Jaffray 21st Annual Health Care Conference [0] Integrated Electrical Services Awarded Contract to Provide Electrical Systems for U.S. Army Medical Research Institute of Infectious Diseases [0] KTA Capital Arranges an AU$6.7 Million Private Placement by Neuren Pharmaceuticals

...a, Dec. 14 /Xinhua-PRNewswire/ -- WuXi PharmaTech ...ical R&D outsourcing services,announced today that...Massachusetts, accompanied by other members of Mas...paid a visit to the company on December 7,in Shang...in/prnh/20040705/CNM002LOGO ), Massachusetts Chi...

... Dec. 14 A&G Pharmaceutical announced,today that ...rch Initiative,has awarded A&G an $870,000 grant t...measuring levels of A&G,s proprietary breast cance... breast cancer patients. Results of,the studies co...that would,enable early detection of breast cancer...

...ec. 13 Give the person on your list who,has every...ical Mystical,Pen by world-renowned artist, Karen ...f Magical Mystical Tour,abstracts, currently exhib...Juried Competition at Mills Pond House Gallery in ...Sperling,s work takes the viewer on a high octane ...

Other Biology Technology:Massachusetts Governor Deval L. Patrick Pays Visit to WuXi PharmaTech 2 Massachusetts Governor Deval L. Patrick Pays Visit to WuXi PharmaTech 3 A&G Pharmaceutical Receives $870,000 Grant from Avon Foundation to Advance Innovative Blood Diagnostic Test for Early Detection of Breast Cancer 2 A&G Pharmaceutical Receives $870,000 Grant from Avon Foundation to Advance Innovative Blood Diagnostic Test for Early Detection of Breast Cancer 3 Artistic Magical Mystical Tours 2

Massachusetts Governor Deval L. Patrick Pays Visit to WuXi PharmaTech A&G Pharmaceutical Receives $870,000 Grant from Avon Foundation to Advance Innovative Blood Diagnostic Test for Early Detection of Breast Cancer Artistic Magical Mystical Tours

... and Protein G bind specifically to Fc regions of ...ein G conjugates are commonly used as affinity ads... immunoglobulin subtypes from serum, hybridoma asc... biological fluids. These reagents are also common...

CORNING PETRI DISH, 100 X 20 MM, PS, ULTRA LOW BINDING, STERILE from Sigma-Aldrich

...se-iT™ One-Step Kit is the ultimate in conven...It has been specifically designed to streamline th...it combines the unique Reverse-iT™ Blend of R...erase to provide a highly sensitive, reproducible ...

Biology Products:

REC. PROTEIN G - SEPHAROSE from Invitrogen CORNING PETRI DISH, 100 X 20 MM, PS, ULTRA LOW BINDING, STERILE from Sigma-Aldrich Reverse-iT One-Step Kit, ReddyMix from ABgene REC PROTEIN A - SEPHAROSE from Invitrogen

( with recessive forms accounting for re...)Researchers discover new gene responsible for brittle bone disease