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Researchers discover new details about HIV-1 entry and infection

en infected with HIV-1 while LC may harbor viable virus for some time before spreading it to other cells.

These results reveal that it is necessary to consider mechanisms of viral entry into both CD4+ T and LC when searching for an effective way to interfere with infection through the vaginal epithelium. "Our findings provide exciting definitive insights into the initial events of HIV-1 infection in the human vagina, which can guide the design of effective strategies to block local transmission and prevent HIV-1 spread," concludes Dr. McElrath.
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Source:Cell Press


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