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Researchers discover mechanism that determines when detailed memories are retained

c frequencies. However, when the stimulation was greater (leading to the higher level of acetylcholine release), the rats also remembered the specific frequencies.

"We have always known that acetylcholine plays a major role in learning and memory," Weinberger said. "For example, the major treatments currently available for Alzheimer's disease work by making more acetylcholine available in the brain. Finding ways to control the levels of this key transmitter would be crucial for treating a number of memory-related disorders."

Weinberger is a pioneer in research in the field of learning and memory in the auditory system. In a study published in 2005, he discovered a neural coding mechanism that the brain relies upon to register the intensity of memories based on the importance of the experience. The study presented the first evidence that a "memory code" of any kind may exist. His laboratory also was the first to induce a specific memory by stimulating the system involving acetylcholine in the brain, setting the stage for the latest findings.
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Source:University of California - Irvine


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