Navigation Links
Researchers discover how bacteria sense their environments

When humans taste or smell, receptors unique to each nerve cell detect the chemical and send signals to the brain, where many cells process the message to understand what we are smelling or tasting. But a bacterium is just a single cell, and it must use many different receptors to sense and interpret everything around it.

Bacteria can sense in their environments changes in molecular concentrations as small as 0.1 percent, the equivalent of one drop diluted in a pool of a 1,000 drops. How do they do it?

New Cornell research, highlighted on the cover of the May issue of Nature Structural and Molecular Biology, reveals that receptors assemble into a kind of cooperative lattice on a bacterium's surface to amplify infinitesimal changes in the environment and kick off processes that lead to specific responses within the cell.

"Bacteria sense a lot of different things. But assume it's a sugar molecule that a bacterium needs as a nutrient -- even a 0.1 percent change in concentration can be detected, and this sensitivity is maintained over five orders of magnitude in nutrient concentration," said Brian Crane, assistant professor of chemistry and chemical biology and corresponding author of the paper. "Biologically, I know of no other system that is so sensitive over such a large range."

Crane believes the kind of cooperative lattice found in bacterial receptors may in fact point to a general mechanism for cellular signaling and serve as inspiration for developing molecular devices. Such devices could be used to sense a wide range of chemicals, light, ionic strength (salt), pH and heavy metals with great sensitivity, gain and dynamic range. Scientists are interested in developing synthetic systems with such sensing properties as well as engineering bacteria that respond to stimuli such as pollutants or explosives.

Using a combination of X-ray crystallography to determine the structure of receptors and enzymes and a novel spectroscopi
'"/>

Source:Cornell University News Service


Page: 1 2

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Researchers discover how bacteria sense their environments

(Date:4/15/2014)... fixed carbon and energy for nearly all life on ... mysterious. For example, little is known about how it ... More fundamentally, we do not know the full list ... photosynthesis in any organism. , , A type of ... a leading subject for photosynthesis research. Despite its importance ...
(Date:4/15/2014)... Mass. Diana Lados, associate professor of ... and founding director of the university,s Integrative ... major career achievement awards from leading engineering ... Detroit, SAE International, a global association of ... experts in the automotive, aerospace, and commercial ...
(Date:4/15/2014)... social behavior has developed over the course of evolution, ... gained new insights from the study of earwigs. "Young ... siblings share what is available amongst themselves, especially when ... the Evolutionary Biology section of the Institute of Zoology ... of biologists from Mainz University and the University of ...
Breaking Biology News(10 mins):WPI's Diana Lados honored by SAE International and Minerals, Metals, and Materials Society 2WPI's Diana Lados honored by SAE International and Minerals, Metals, and Materials Society 3WPI's Diana Lados honored by SAE International and Minerals, Metals, and Materials Society 4WPI's Diana Lados honored by SAE International and Minerals, Metals, and Materials Society 5Sibling cooperation in earwig families gives clues to early evolution of social behavior 2
... world record for the most densely populated space and now ... the most species rich area on earth. The team,s findings, ... the record is contested between South America,s tropical rainforests and ... species in one space and the questions it raises have ...
... Professor Russell Chesney, M.D. believes he knows what was ailing ... Carol." Based on detailed descriptions of both the symptoms ... that Tiny Tim suffered from a combination of rickets and ... 5 edition of Archives of Pediatrics and Adolescent Medicine ...
... found a way to create temporary holes in the membranes ... will be published in JoVE, the Journal of Visualized ... idea for this method when we wanted to be able ... forces on cells," said paper-author Dr. Delphine Dean. She ...
Cached Biology News:European grasslands challenge rainforests as the most species-rich spaces on Earth 2Researchers print live cells with a standard inkjet printer 2
(Date:1/15/2014)... 2014 The Microcompetition with Foreign DNA ... disease. One of these latent viruses is the Epstein ... rheumatoid arthritis (RA). Rheumatoid arthritis (RA) is a chronic ... by the theory, a study found that RA patients ... (1). , What is Microcompetition? , Dr. Hanan ...
(Date:1/15/2014)... Sunnyvale, CA (PRWEB) January 15, 2014 ... of high throughput research solutions, today announced that ... companies, has received delivery of Freeslate’s CM ... form screening. , Lupin, headquartered in Mumbai, ... quality, affordable generic and branded formulations and Active ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Date: Friday, ... p.m. , Location: Warrington Country Club, 1360 Almshouse Road, ... Foundation, the only national nonprofit organization solely dedicated to ... quality of life for those affected worldwide, will host ... Warrington Country Club in Warrington, Pa. , Each ...
(Date:1/14/2014)... , Jan. 14, 2014  3D Communications, a leading provider ... major scientific, regulatory, business, and media events in ... , today announced its former associate Virginia Cox , ... office. Virginia Cox re-joins ... Commissioner for the Office of External Affairs at the U.S. ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2Former FDA Associate Commissioner Returns To 3D Communications 2
... have made a breakthrough in understanding the effect on ... The discovery could lead to more accurate forecasting of ... , Crozier is an associate professor in ASU,s School ... of Liberal Arts and Sciences and the Ira A. ...
... SGXP ) today announced its financial results for the ... months ended June 30, 2008, the,Company posted revenues of $4.3 ... months ended June 30, 2008, revenues were $21.3 million and ... month period includes $10.8,million of revenue earned in the first ...
... Verenium Corporation,(Nasdaq: VRNM ), a leading ... the development of high-performance specialty enzymes, announced,today that ... present at,the upcoming Canaccord Adams 28th Annual Global ... 10:30 a.m. ET on Thursday, August 14,and will ...
Cached Biology Technology:Forward step in forecasting global warming 2Forward step in forecasting global warming 3SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 2SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 3SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 4SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 5SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 6SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 7SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 8SGX Pharmaceuticals Announces Financial Results for the Three and Six Months Ended June 30, 2008 9Verenium Corporation to Present at Canaccord Adams 28th Annual Global Growth Conference 2Verenium Corporation to Present at Canaccord Adams 28th Annual Global Growth Conference 3
... exchange media are rigid macroporous hydrophilic media. ... rates at moderate pressures, while the macroporous ... the hydrophilic matrix reduces nonspecific binding. Macro-Prep ... anion exchanger with very high flow rates ...
... Spring offers a large collection of ... fetal tissuea, cell lines, and mouse ... in pHD9 vector. The size of ... be from 200bp to 1000bp by ...
... Corticosterone kit is a competitive enzymeimmunoassay (EIA) ... mouse or rat serum or plasma. Corticosterone ... in rats and mice, and in most ... reptiles. Most mammals produce both corticosterone and ...
Mouse monoclonal [1.F.1] to Yersinia pestis F1 antigen ( Abpromise for all tested applications). Antigen: Purified F1 antigen of Y. pestis vaccine strain EB....
Biology Products: