Navigation Links
Researchers devise new technique for creating human stem cells

Researchers have developed a new technique for creating human embryonic stem cells by fusing adult somatic cells with embryonic stem cells. The fusion causes the adult cells to undergo genetic reprogramming, which results in cells that have the developmental characteristics of human embryonic stem cells.

This approach could become an alternative to somatic cell nuclear transfer (SCNT), a method that is currently used to produce human stem cells. SCNT involves transferring the nuclei of adult cells, called somatic cells, into oocytes in which scientists have removed the nuclei.

The researchers said that -- while the technique might one day be used along with SCNT, which involves the use of unfertilized human eggs -- technical hurdles must be cleared before the new technique sees widespread use. It is more likely that the new technique will see immediate use in helping to accelerate understanding of how embryonic cells "reprogram" somatic cells to an embryonic state.

The researchers published their findings in the August 26, 2005, issue of the journal Science. Senior author Kevin Eggan and Howard Hughes Medical Institute investigator Douglas A. Melton, both at Harvard University, led the research team, which also included Harvard colleagues Chad Cowan and Jocelyn Atienza.

In theory, researchers can induce embryonic stem cells to mature into a variety of specialized cells. For that reason, many researchers believe stem cells offer promise for creating populations of specialized cells that can be used to rejuvenate organs, such as the pancreas or heart, that are damaged by disease or trauma. Stem cells also provide a model system in which researchers can study the causes of genetic disease and the basis of embryonic development.

Eggan, Melton and their colleagues decided to pursue their alternative route after other researchers had shown that genetic reprogramming can occur when mouse somatic cells are fused to mouse embryo
'"/>

Source:Howard Hughes Medical Institute


Page: 1 2 3 4

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
(Date:10/6/2008)...An experimental anti-cancer drug can prevent -- an... damage in a mouse model of progeria, a rare genet...human premature aging, National Institutes of Heal...udy published in the Oct. 6 early online edition o...nces, a team led by Francis S. Collins, M.D., Ph....
(Date:10/6/2008)...,, When the Global Mammal Assessment project re...ation Congress in Barcelona, Spain, there will be ...tened list. , The species of mammals from Texas ...based upon the IUCN categories are commonly known ...t, Myotis sodalis, robust cottontail, desert pocke...
(Date:10/6/2008)...As the ongoing financial crisis has clearly illust...l be addressing the nation,s severe economic crisi...nt to basic scientific research is one of the most...ensure our long-term fiscal health, The Science Co...attached) to the moderator of tomorrow,s president...
(Date:10/6/2008)..., A Brazilian palm berry, popular health food thou...ve its purported benefits better understood. , I...h-sigh-EE) berry has proven its ability to be abso... and pulp. That finding, by a team of Texas AgriLi...issue of the Journal of Agricultural and Food Che...
Breaking Biology News(10 mins):Anti-cancer drug prevents, reverses cardiovascular damage in mouse model of premature aging disorder 2Anti-cancer drug prevents, reverses cardiovascular damage in mouse model of premature aging disorder 37 Texas mammals listed as threatened on Global Mammal Assessment 2The Science Coalition's '10 questions' for the presidential debate 2Research shows Brazilian acai berry antioxidants absorbed by human body 2Research shows Brazilian acai berry antioxidants absorbed by human body 3Regenstrief Institute tapped by CDC to combat potentially catastrophic disease outbreaks 14024 1Regenstrief Institute tapped by CDC to combat potentially catastrophic disease outbreaks 14024 2Pew Institute teams with Chantecaille Cosmetics to protect global marine life 2463 1Pew Institute teams with Chantecaille Cosmetics to protect global marine life 2463 2Burgerville Honored for Dedication to Employees and Innovative Workplace Practices 14022 1Burgerville Honored for Dedication to Employees and Innovative Workplace Practices 14022 2Burgerville Honored for Dedication to Employees and Innovative Workplace Practices 14022 3Highmark Blue Shield and National Association Name Area Hospitals as Blue Distinction Centers for Complex and Rare Cancers 14019 1Highmark Blue Shield and National Association Name Area Hospitals as Blue Distinction Centers for Complex and Rare Cancers 14019 2Highmark Blue Shield and National Association Name Area Hospitals as Blue Distinction Centers for Complex and Rare Cancers 14019 3
...brain has ways of refracting sensory input in defi...he placebo effect, when simple sugar pills or iner...ase pain or have some other beneficial physiologic...t and prompts the body to respond is largely a mys...have begun to peel back some of the neurological s...
...human eye, but how does a sunflower achieve its st... delicate symmetry? , That was the question tackle...o have answered one of biology,s enduring question...tailed simulation of how plants grow into recogniz...of phyllotaxis" published in this week,s edition o...
... to treat melanoma has demonstrated promising effe...hers at The Wistar Institute. About a third of mel...The study appears in the current issue of Cancer R...ll protein called a peptide found in approximately... to stimulate immune cells called killer T cells t...
...stories of diverse species has shown that sexual r... and tends to decrease lifespan rather than increa... Burda from the University of Duisburg-Essen shows...e true as well. , The authors, studying captive Za...ding data gathered over the course of more than 20...
Other Biology News:Great (taste) expectations: Study shows brain anticipates taste, shifts gears 2Pleasing plant shapes explained by new computer model 2Melanoma vaccine strategy shows promise in laboratory experiments 2
(Date:10/7/2008)...ected to aid drug discovery by allowing for the ra...gle reaction, ST. LOUIS, Oct. 7 /PRNewswire-First...o announce that it has signed an exclusive licensi...bana-Champaign allowing,Sigma-Aldrich to offer res...ogates for use in Suzuki-Miyaura coupling to resea...
(Date:10/7/2008)...s to focus on new patient data supporting the Ross...ynerGraft processed human heart .../- CryoLife, Inc. (NYSE: C...ocessing company, announced today,that cardiovascu...e in the,Ross Summit 2008, a two-day surgical cong...
(Date:10/7/2008)...Institutes of Health, The Infectious Disease Resea...Launch and Board of Advisors, SEATTLE, Oct. 7 /PR...,Initiative today announced its first acquisition ...osis (TB) drug candidates. Agreements were reached...nd the Microbial Chemistry,Research Foundation (MC...
(Date:10/7/2008)... Oct. 7 /- BioEnergy International, L...r and manufacturer of,next-generation, renewable b...f Norman R. Augustine to its Board of Advisors eff...f distinguished leadership and innovation,at the h...g in his role as,Chairman and Chief Executive Offi...
Breaking Biology Technology:Sigma-Aldrich and the University of Illinois Offer New Boronic Acid Surrogates to Researchers Worldwide Through Licensing Agreement 2Sigma-Aldrich and the University of Illinois Offer New Boronic Acid Surrogates to Researchers Worldwide Through Licensing Agreement 3CryoLife Hosts Worldwide Surgical Congress for the Ross Procedure 2CryoLife Hosts Worldwide Surgical Congress for the Ross Procedure 3CryoLife Hosts Worldwide Surgical Congress for the Ross Procedure 4Update: The Lilly TB Drug Discovery Initiative Begins Work on New Compounds to Fill Early-Stage TB Drug Pipeline 2Update: The Lilly TB Drug Discovery Initiative Begins Work on New Compounds to Fill Early-Stage TB Drug Pipeline 3Update: The Lilly TB Drug Discovery Initiative Begins Work on New Compounds to Fill Early-Stage TB Drug Pipeline 4Update: The Lilly TB Drug Discovery Initiative Begins Work on New Compounds to Fill Early-Stage TB Drug Pipeline 5BioEnergy International, LLC Announces Norman R. Augustine to Join Advisory Board 2BioEnergy International, LLC Announces Norman R. Augustine to Join Advisory Board 3
...sons next career move is like attempting to count ...the glass and make an educated guess but you rare...ortant disclaimer aside, here are some long-shot p...doing after (and if) he leaves as secretary of the... those who enjoy political side bets, Ill even pro...
...Madison, Wis. The University of Wisconsin-Madiso...eceive a grant from the Intel Advanced Computing ...ng conference in Philadelphia. , ,The recipient of...ler , a UW-Madison professor of computer sciences.... their work on scalable performance installation, ...
...ines pushing sales are great for getting a custome...stage for a second or two. , ,Some taglines catch ..., causing them to escape the trap and run away. , ...composed slogans promoting various branding worldw...rporations make extraordinary efforts to capture t...
...e worlds most powerful economy by producing and at...dvantage away?" , ,This provocative statement ope...tivity Crisis, which appeared in the October 2004 ...xt of the article can be purchased online here )....he economic importance of the Creative Class the 3...
Other Biology Technology:Could Tommy Thompsons next stop be Transportation, Homeland Security, or the private sector? 2Could Tommy Thompsons next stop be Transportation, Homeland Security, or the private sector? 3Scalable performance monitoring software draws grant from Intel 2Super advertising slogans, and super costs 2Super advertising slogans, and super costs 3Super advertising slogans, and super costs 4Is America Inc.s brand diminishing? 2Is America Inc.s brand diminishing? 3Is America Inc.s brand diminishing? 4