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Researchers develop buckyballs to fight allergy

ally, the buckyballs are able to prevent mast cells from releasing histamine.

Mast cells are responsible for causing allergic response and are packed with granules containing histamine. They are present in nearly all tissues except blood. When mast cells are activated, inflammatory substances such as histamine, heparin and a number of cytokines are rapidly released into the tissues and blood, promoting an allergic response.

The researchers found that the unique structure of the buckyball enables it to bind to free radicals dramatically better than any anti-oxidant currently available, such as vitamin E. Free radicals are molecules that cause oxidative stress, which experts believe may be the basis of aging.

“The immune system both protects us and causes harm, so we are always interested in finding new pathways to help manage the harmful effects,” said Kepley.
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Source:Virginia Commonwealth University


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