Navigation Links
Researchers Discover Gene That Determines Asthma Susceptibility By Regulating Inflammation

f susceptibility to allergen-mediated asthma,?says Biswal. “Nrf2 regulated pathways seem to intervene inflammation at several points.?/p>

The findings provide a better understanding of the human body’s defense mechanisms to stress, which may hold clues to better control the inflammation process and improve control over asthma and its symptoms. Study coauthor Tirumalai Rangasamy, PhD said that the next step for researchers will be to look for molecular mechanism of regulation of asthmatic inflammation by Nrf2 and determine if there are alterations in the response of Nrf2 gene in asthma-prone humans. Future studies will determine the therapeutic potential of targeting Nrf2 for treatment of asthma.

“Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice?was written by Tirumalai Rangasamy, Jia Guo, Wayne A. Mitzner, Jessica Roman, Anju Singh, Allison D. Fryer, Masayuki Yamamoto, Thomas W. Kensler, Rubin M. Tuder, Steve N. Georas and Shyam Biswal.

The study was supported by grants from the National Institutes of Health, the National Institute of Environmental Health Sciences, the Maryland Cigarette Restitution Fund, the Flight Attendant Research Institute and the Thomas and Carol McCann Innovative Research Fund for Asthma and Respiratory Disease.


'"/>

Source:Johns Hopkins University Bloomberg School Of Public Health


Page: 1 2

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Researchers find how protein allows insects to detect and respond to pheromones
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. Researchers reveal the infectious impact of salmon farms on wild salmon
5. Researchers identify target for cancer drugs
6. Researchers discover molecule that causes secondary stroke
7. Researchers find missing genes of ancient organism
8. Researchers trace evolution to relatively simple genetic changes
9. Researchers add new tool to tumor-treatment arsenal
10. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
11. VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Post Your Comments:
(Date:12/5/2014)... Utah , Dec. 4, 2014  Tute Genomics, ... raised $2.3 million in Series A1 funding led by ... investors also participated in the investment round. ... the healthcare community adopts next-generation sequencing and seeks new ... said Reid Robison , MD MBA, and CEO ...
(Date:12/3/2014)... , Dec. 2, 2014   Marvin Test ... innovative test solutions for military, aerospace, and manufacturing ... of its successful TS-900 PXI semiconductor test ... features of high-end systems to customers at a ... compared to traditional ATE. "Our ...
(Date:11/21/2014)... November 18, 2014 According to ... by Systems (Video, RFID, Access Control, Intrusion Detection, Parking ... Banks, Government), Component Service Geography - Global Forecasts to ... is projected to be around $25 Billion in 2014 ... growing at a CAGR of 8.69%. Browse ...
Breaking Biology News(10 mins):Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 2Tute Genomics Raises $2.3 Million to Scale Up Cloud-Based Genome Analytics and Accelerate Personalized Medicine 3Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 2Marvin Test Solutions Brings New Capabilities to PXI-Based Semiconductor Test with TS-960 3Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3
... for drinking water but about 20 years ago the once ... toxic blue-green algae which can damage the liver, intestines and ... Knoxville, will be working on an international team funded by ... resolve the ecosystem balance in the lake. Their work could ...
... This press release is available in Spanish . ... scientist has found a "green" alternative to a type ... the accumulation of heavy metals in waterways. Ornamental ... copper and zinc. But fertilizers that provide these micronutrients ...
... dietary fats are not created equal. Some types of fats have ... like those often found in plants and fish, have well documented ... destructively to some fats but not others? A new ... Biology suggests the answer may lie in how different fats ...
Cached Biology News:University of Tennessee Team receives NSF support to study toxic water in China 2A greener way to fertilize nursery crops 2The Quarterly Review of Biology: Why some fats are worse than others 2
(Date:12/19/2014)... Reports from CDC show approximately 117 ... or more chronic health conditions - including cardiovascular disease, ... of these diseases, but may not eliminate the severe ... implanted nerve stimulation devices today offer relief, they require ... induce side effects. , To eliminate the need ...
(Date:12/19/2014)... The empty capsules market is experiencing growth ... technological innovations in the empty capsules market. The ... growth of the empty capsules market. , Get ... of Report , The report will enrich both ... to gauge the pulse of the market which ...
(Date:12/19/2014)... N.Y. , Dec. 18, 2014 Egenix, Inc. ... has been elected Chairman of the Board, to succeed ... and CEO, but will continue as a member of the ... he has added to the company over almost twenty years, ... The Board of Directors has established a Search Committee ...
(Date:12/17/2014)... December 16, 2014 The Activated ... 2013, which is why IBISWorld updated its original industry ... to benefit from an intensified focus on environmental policy. ... new emission standards for power plants and a range ... to IBISWorld Industry Analyst Sarah Kahn, “a range of ...
Breaking Biology Technology:Draper Wins GSK Funding for Smaller, Smarter Implantable Devices 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 2Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 3
... to innovation, American Family Insurance's Information Services Division ... The direction comes from within, and Byrne Chapman, vice president ... familiar phrase: nothing ventured, nothing gained. To build a culture ... modeled after employee-driven, quality-control programs. , ,While management experts ...
... plans to erect as many as five more buildings on ... about needs well beyond its existing base of 2,500 employees, ... administrative officer, said the company anticipates adding 1,500 more individual ... 2,500. In addition, there remains plenty of room on the ...
... protection firms could be the answer to a question you ... ,The Internet does connect you with your customers - and ... that could damage your reputation and sales. Here are several ... simple to the sophisticated, and suggestions for dealing with them. ...
Cached Biology Technology:CIO Leadership Series: Byrne Chapman, American Family Insurance 2CIO Leadership Series: Byrne Chapman, American Family Insurance 3CIO Leadership Series: Byrne Chapman, American Family Insurance 4Epic Systems will build well beyond current staff size 2Protecting your business against online brand abuse 2Protecting your business against online brand abuse 3
SDS-OutT Precipitation Reagent...
... Removal , , Removes ... cross-reactivity with other proteins , Simple, just ... Economical new surface technology, not based on ... with protein analysis. SurfactAway offers a simple ...
... speed and excellent temperature uniformity. Protocols that ... can be run without any modifications. The ... for 48 or 96 wells. In addition, ... applications are available. The High Precision Smart ...
General description: MaxiSorp TM surface is ideal for arraying molecules with mixed hydrophilic/hydrophobic domains such as proteins ID clarifier: Maxisorp(tm) with lid...
Biology Products: