Navigation Links
Research team identifies new Alzheimer's gene

ng of treatment,” said Dr. Chris Heward, President of Kronos Science Laboratory.

Until recently, researchers lacked the technology to examine the genetic components of a disease at such a high-level of detail. By utilizing the Affymetrix 500K Arrays, the study’s researchers rapidly produced a genetic map of each brain tissue sample and isolated the GAB2 gene relatively quickly.

“This Alzheimer's disease breakthrough is another powerful example of a fundamental life science discovery made by an Affymetrix customer. Our latest microarray technology continues to accelerate research at an unprecedented pace by enabling scientists to better identify the specific genetic variations associated with complex diseases,” said Kevin King, President of Life Sciences Business and Executive Vice President at Affymetrix.

In addition to surveying an unprecedented number of genetic markers in each person’s DNA, the researchers capitalized on extremely rigorous criteria to determine whether or not their volunteers had Alzheimer’s. For instance, the study included more than 1000 brain donors confirmed to either have Alzheimer’s disease or be free of the disorder at autopsy. This study resulted in a comprehensive set of high-quality data to be made publicly available to the research community. The researchers believe that deposition of this data set in the public domain will open a new era in Alzheimer research. When a scientist suspects a particular gene or pathway maybe implicated in Alzheimer’s disease, they will use these data to see if there is genetic evidence supporting their idea. Reviewing these data in an hour will permit them to save months of work and thousands of dollars to achieve the same result. Moreover, it paves the way for even more advanced studies using larger sample populations, more powerful array chips that can distinguish more genetic markers, and more sophisticated methods of analyzing the data.
'"/>

Source:The Translational Genomics Research Institute


Page: 1 2 3

Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
3. Researchers find how protein allows insects to detect and respond to pheromones
4. Researchers Uncover Key Step In Manufacture of Memory Protein
5. Research advances quest for HIV-1 vaccine
6. Research on Worms Yields Clues on Aging
7. Researchers reveal the infectious impact of salmon farms on wild salmon
8. Researchers identify target for cancer drugs
9. Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
10. Researchers discover molecule that causes secondary stroke
11. Researchers find missing genes of ancient organism

Post Your Comments:
(Date:11/23/2009)...ersity of Southern California biomedical engineer ...op a new tool to help clinicians distinguish cardi...ronic problems manageable with drugs and lifestyle...inserted into the arteries feeding the heart, offe... of these blood vessels, often revealing deposits ...
(Date:11/23/2009)...tional Institute of General Medical Sciences (NIGM...), is investing $42.3 million for grants in scient...GO)." NIH developed the GO grant program to stimul...s provided by the American Recovery and Reinvestme...jects that promise to have a significant impact on...
(Date:11/23/2009)... Mara Romeo Casabona is Director of the Interunive...t Deusto University and the University of the Basq...f jurists but also has other experts such as resea...e and even specialists in ethics. , The Interuni... at the Universities of Deusto and the Basque Coun...
Breaking Biology News(10 mins):Stable plaque or heart attack plaque? USC researcher builds new sensor to tell which is which 2NIGMS invests in scientific Grand Opportunities with Recovery Act funds 2NIGMS invests in scientific Grand Opportunities with Recovery Act funds 3Research and legislation should go hand in hand, as much as possible 2Free Choice to Petition Japanese Government for Right to Choose Private Health Insurance in Lieu of Japan 26apos 3Bs Universal Health Care 55794 1Free Choice to Petition Japanese Government for Right to Choose Private Health Insurance in Lieu of Japan 26apos 3Bs Universal Health Care 55794 2Free Choice to Petition Japanese Government for Right to Choose Private Health Insurance in Lieu of Japan 26apos 3Bs Universal Health Care 55794 3Two Powerful Companies One Powerhouse in Protection 55790 1Two Powerful Companies One Powerhouse in Protection 55790 2Stemedica Achieves Major Milestone Company Receives License to Manufacture Clinical Grade Stem Cells 4924 1Stemedica Achieves Major Milestone Company Receives License to Manufacture Clinical Grade Stem Cells 4924 2
...e often lose their sense of smell and their appeti... be able to feed on humans and spread malaria. A t...insect disease that will infect mosquitoes and imp...$100,000 grant from the Bill and Melinda Gates Fou..., the researchers were among 81 projects funded fr...
...s at the Universit de Montreal (UdeM) and the Mont...ty have discovered that cells which normally suppo...e and major role in the death of neurons in the ey...al of Neuroscience , may lead to more streamlined ...logical disorders, including glaucoma and retinal ...
... from Australia,s Great Barrier Reef is that we ha...ty in turn protects us. , That,s the message from...cellence for Coral Reef Studies and James Cook Uni...of Science,s prestigious Fenner medal for his pion...p and maintain their amazing diversity. , "The Gr...
Other Biology News:Penn State entomologists seek fungus to blunt mosquitoes' sense of smell 2Cell's split personality is a major discovery into neurological diseases 2A big lesson from the reef 2A big lesson from the reef 3
(Date:11/20/2009)...20 Dendreon Corporation ...d and Drug Administration (FDA) provided written a...s License Application (BLA) for PROVENGE® (si...ssigned a Prescription Drug User Fee Act (PDUFA) d...to Dendreon,s amended BLA. Dendreon is seeking li...
(Date:11/20/2009)...v. 20 Cell Therapeutics,... that the Ninth Circuit Court of Appeals reversed ...uld be allowed to pursue all of its claims against...rict Court for trial. CTI filed a complaint again...rsement consultant for CTI,s product TRISENOX, in ...
(Date:11/19/2009)... to be able to charge their cell phones and other ...recent discovery made by UC San Diego engineers co...that could do just this. , In recent research, ...Bandaru, a professor in the UCSD Department of Mec...uate student Mark Hoefer, have found that artifici...
(Date:11/19/2009)... Nov. 19 Dr. Mate Hidvegi, invento... to a press release issued on November 17 by Birop...making false and self-serving statements about its...Hidvegi stated from his office in Budapest, Hungar...vemar does not apply to AveULTRA, www.aveultra.c...
Breaking Biology Technology:Dendreon Receives FDA Acknowledgement of Complete Response 2Dendreon Receives FDA Acknowledgement of Complete Response 3Cell Therapeutics Wins Federal Appeal to Pursue $22.8 Million Claim Against The Lash Group 2Nanotube defects equal better energy and storage systems 2American BioSciences Rebuts Misleading Statements Made by Hungarian Competitor 2
...an, was promoted to president of the General Elect...in May to replace Gregory Lucier, who left to beco...ormation technologies and most of GE Medical,s mon...ate executive searching for a plum growth opportun...E CEO and Chairman Jeffery R. Immelt, successor to...
...eam video from their Charleston and Morgantown cam...omputer at their convenience. All of WVUs core gra...the web beginning this fall semester. , ,We need ...ach the next generation, said Rose Ann DiMaria, as...ing. By using Mediasite Live to provide Web-based ...
...ns such as the Small Business Development Center, ...men,s Business Initiative Corp. in Milwaukee and w...ubator Center tenants and other area businesses. ...on providing management for the T.E.C. Incubator C...tnership between MATC and McAllen Properties, a co...
Other Biology Technology:CEO Wilson Defines GE's Health-IT Customer 2CEO Wilson Defines GE's Health-IT Customer 3CEO Wilson Defines GE's Health-IT Customer 4Sonic Foundry Facilitates Nursing Education 2Sonic Foundry Facilitates Nursing Education 3
...isposable microfiltration devices for the fast and...amples in the range 100 l to 500 l. They can be us...ge tubes. Product Features: High-flux Polyethers...lume ( Fast and reproducible performance Applica...
...posable spin filtration device especially designed...plasmid purification procedures. , ,The Cl...ion device especially designed to aid the clarific... procedures. The neutralized lysate is centrifuged...
Corning Spin-X Centrifuge Tube Filters from Sigma-Aldrich
...ull; Reusable, press-to-seal gasket and cover slip...assembled for hybridizing and imaging thick or fre... 13 mm diameter. Build up to three chambers per sl...tion and leaking even when submerged. RNase-free, ...
Biology Products: