Navigation Links
Research may provide new link between soft drinks and weight gain

A University of Cincinnati (UC) study provides new evidence that drinking large amounts of beverages containing fructose adds body fat, and might explain why sweetening with fructose could be even worse than using other sweeteners.

Researchers allowed mice to freely consume either water, fructose sweetened water or soft drinks. They found increased body fat in the mice that drank the fructose-sweetened water and soft drinks--despite that fact that these animals decreased the amount of calories they consumed from solid food.

This, said author Matthias Tschöp, MD, associate professor in UC's psychiatry department and a member of the Obesity Research Center at UC's Genome Research Institute, suggests that the total amount of calories consumed when fructose is added to diets may not be the only explanation for weight gain. Instead, he said, consuming fructose appears to affect metabolic rate in a way that favors fat storage.

"Our study shows how fat mass increases as a direct consequence of soft drink consumption," said Dr. Tschöp.

The research appears in the July 2005 issue of Obesity Research, the official journal of the North American Association for the Study of Obesity (NAASO).

Consumption of sweetened foods and beverages containing sucrose and high-fructose corn syrup?particularly carbonated soft drinks and some juices and cereals--has been thought to be a leading cause of obesity. A widely used sweetener derived from corn, high-fructose corn syrup is similar to sucrose (table sugar) in its composition, about half glucose and half fructose.

Dr. Tschöp's lab used novel body composition analyzers that use magnetic resonance technology to carefully monitor body fat in mice.

All the mice began the study at an average weight of 39 grams. Those consuming the fructose-sweetened water showed significant weight gain over the course of the study, with an average final weight of 48 grams--compared with averages below 44 grams for the other groups--and had about 90 percent more body fat than the mice that consumed water only.

Total caloric intake was lower in the mice that consumed the fructose-sweetened water than in the other groups, except for the control animals provided with water only.

"We were surprised to see that mice actually ate less when exposed to fructose-sweetened beverages, and therefore didn't consume more overall calories," said Dr. Tschöp. "Nevertheless, they gained significantly more body fat within a few weeks."

Results from an earlier study in humans led by Peter Havel, DVM, PhD, an endocrinology researcher at the University of California, Davis, and coauthored by Dr. Tschöp, found that several hormones involved in the regulation of body weight, including leptin, insulin and ghrelin, do not respond to fructose as they do to other types of carbohydrates, such as glucose.

Based on that study and their new data, the researchers now also believe that another factor contributing to the increased fat storage is that the liver metabolizes fructose differently than it does other carbohydrates.

"Similar to dietary fat, fructose doesn't appear to fully trigger the hormonal systems involved in the long-term control of food intake and energy metabolism," said coauthor Dr. Havel.

The researchers say that further studies in humans are needed to determine if high-fructose corn syrup in soft drinks is directly responsible for the current increase in human obesity.


'"/>

Source:University of Cincinnati


Related biology news :

1. Researchers discover way to make cells in the eye sensitive to light
2. Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
3. Researchers find how protein allows insects to detect and respond to pheromones
4. Researchers Uncover Key Step In Manufacture of Memory Protein
5. Research advances quest for HIV-1 vaccine
6. Research on Worms Yields Clues on Aging
7. Researchers reveal the infectious impact of salmon farms on wild salmon
8. Researchers identify target for cancer drugs
9. Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
10. Researchers discover molecule that causes secondary stroke
11. Researchers find missing genes of ancient organism
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/19/2016)... TORONTO , 19 de diciembre de 2016  Mosaic Biomedicals ... el desarrollo acelerado de MSC-1, un anticuerpo humanizado que se espera ... en 2017, con múltiples sitios previstos a lo largo de Europa ... MSC-1 ... factor inhibidor de leucemia (LIF), una citoquina pleiotrópica que se sobreexpresa ...
(Date:12/15/2016)... and BADEN-BADEN, Germany , December ... leading global financial services provider, today announced an agreement with ... behavioural biometrics, to join forces. The partnership will enable clients ... strategies in compliance with local data protection regulation. ... In order to ...
(Date:12/15/2016)... Mich. , Dec. 15, 2016  There is ... car doors or starting the engine. Continental will demonstrate ... Las Vegas . Through the combination ... Start and Entry) and biometric elements, the international technology ... of vehicle personalization and authentication. "The integration ...
Breaking Biology News(10 mins):
(Date:1/18/2017)...  Caris Life Sciences, a leading innovator in ... private funder of pancreatic cancer research, are collaborating ... of immunotherapy in the treatment of pancreatic cancer. ... identify potential trial candidates based on biomarker expression ... study investigators. The Lustgarten Foundation is a sponsor ...
(Date:1/17/2017)... Foreside, Maine (PRWEB) , ... January 17, 2017 ... ... announce the addition of Rheumatoid Factor (RF) to its VALIDATE® SP2 calibration verification ... Rheumatoid Factor in a human serum base. Each VALIDATE® SP2 kit is prepared ...
(Date:1/17/2017)... Jan. 17, 2017  An international team of ... and St. Boniface Hospital Albrechtsen Research Centre/University of ... an unmet health need affecting nearly one in ... Clinical Investigation, their results identify small molecule drugs ... reverse neuronal injury in animal models of metabolic, ...
(Date:1/17/2017)... , Jan. 17, 2017   Pulmatrix, Inc . ... company developing innovative inhaled therapies to address serious pulmonary ... fungal infections in the lungs of CF patients, PUR1900, ... (QIDP) by the U.S. Food & Drug Administration. ... designed to speed the development of novel drugs against ...
Breaking Biology Technology: