Navigation Links
Remote control flies? Fly behavior controlled by laser light

icles to pass through a cell membrane. The small molecule ATP activates the ion channel chosen by the researchers, so ATP became the key. To keep the ATP from binding to the ion channel and jump-starting the nerve cell's activity before the proper moment, Lima and Miesenböck caged the ATP with other chemical compounds that could be removed by the laser light.

Miesenböck says one of the most difficult parts of the experiment was deciding which particular nerve cells to target with the remote control system. "To ascertain that the system actually worked, it wasn't clear how we could measure activation in the neurons in moving, freely behaving organisms," he explains.

The breakthrough, he says, came when they decided to target a small set of nerve cells in the fly called the giant fiber system. The giant fiber system controls very specific, stereotypical movements such as escape movements, jumping, and the beginnings of flight. If the flies engaged in these behaviors after the giant fiber neurons had been outfitted and "operated" with the remote control, Miesenböck and Lima reasoned, they could be sure that their system was working.

After genetically engineering the flies to express the ion channel in the giant fiber system cells and using the tiniest of injections to place the caged ATP inside the flies, the researchers shone a ultraviolet-wavelength laser in brief, millisecond pulses at the flies trapped inside a glass-domed arena. On command, the flies began a series of escape movements--extending their legs, jumping, and opening and rapidly flapping their wings.

The laser-triggered remote controls in the giant fiber system worked about 63 percent of the time, while remote controls placed in other nerve cells that were targets of the giant fiber system worked 82 percent of the time, the researchers concluded. Lima and Misenböck also equipped another set of nerve cells called dopaminergic neurons with the remote controls, boosting the
'"/>

Source:Cell Press


Page: 1 2 3

Related biology news :

1. Remote sheep population resists genetic drift
2. Ancient olfaction protein is shared by many bugs, offering new pest control target
3. Gene variations explain drug dose required to control seizures
4. U-M scientists find genes that control growth of common skin cancer
5. Scientists discuss improved biopesticides for locust control in West Africa
6. Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
7. To control germs, scientists deploy tiny agents provocateurs
8. Cooperation is key—a new way of looking at MicroRNA and how it controls gene expression
9. Master gene controls healing of skin in fruit flies and mammals
10. Internet viruses help ecologists control invasive species
11. DNA constraints control structure of attached macromolecules
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Remote control flies Fly behavior controlled laser light

(Date:5/21/2013)... Mass. , May 21, 2013 Royal ... CX50 xMATRIX, the world,s first portable ultrasound with Philips, ... Echo (ICE) capability. The CX50 xMATRIX with available Live ... Paris at the EuroPCR, official meeting ... May 21-24. Since its launch in 2012, ...
(Date:5/20/2013)... of Minnesota Medical School researchers from the Masonic Cancer ... Brain Tumor Program, have developed a new mouse model ... them to discover new genes and gene pathways driving ... this week in the journal Nature Genetics . ... the lab of David Largaespada, Ph.D., professor in the ...
(Date:5/20/2013)... a compound abundant in the Mediterranean diet takes away ... altering a very specific step in gene regulation, this ... die as scheduled. , One way that cancer cells ... them to die on a regular cycle that is ... by Ohio State University researchers, found that a compound ...
Breaking Biology News(10 mins):Philips CX50 xMATRIX now offers world-class interventional and diagnostic features on single portable system 2U of M researchers develop model for better testing, targeting of MPNST 2The compound in the Mediterranean diet that makes cancer cells 'mortal' 2The compound in the Mediterranean diet that makes cancer cells 'mortal' 3
... pales in comparison with the latest creation of Rice ... of the University of Wisconsin-Madison and Donald Argus of ... put the finishing touches on a 20-year labor of ... the interlocking tectonic plates that account for about 97 ...
... Pediatric researchers analyzing DNA variations in type 1 diabetes ... of genes. Some genes have opposing effects, raising the ... In other cases, a gene variant may act in ... Both type 1 diabetes (T1D) and inflammatory bowel ...
... Energy (DOE) Joint Genome Institute (JGI) has two entries ... Applied Ergonomics Conference held March 22-25, 2010 in San ... category, the DOE JGI,s entry is "Empowering Employees in ... JGI program that help promote awareness of ergonomics and ...
Cached Biology News:Tectonics: Precision is hallmark of 20-year study 2Tectonics: Precision is hallmark of 20-year study 3Genes may exert opposite effects in diabetes and inflammatory bowel disease 2DOE JGI vying for 2010 Ergo Cup 2
(Date:5/21/2013)... (PRWEB) May 21, 2013 Custom ... to reporting eLearning solution using Tin Can API ... dashboard tool. CLD is a leading developer of ... medical device companies worldwide. , Tin Can ... that helps learners and trainers more accurately measure ...
(Date:5/21/2013)... , May 21, 2013 The ... and Transplant Association) is the biggest congress in ... therapy. Nearly 10,000 participants are in Istanbul ... latest research findings. New pioneering studies have been presented: ... FERRIC PYROPHOSPHATE (SFP) ADMINISTERED VIA HEMODIALYSATE REDUCES ESA USE" ...
(Date:5/21/2013)... May 21, 2013 According to ... ( http://www.transparencymarketresearch.com ) "Biochip Products and Services Market (Microarrays, ... Industry Analysis, Size, Share, Growth, Trends and Forecast, 2012 - 2018," the ... and is expected to grow at a CAGR of ... value of USD 4.7 billion in 2018. ...
(Date:5/21/2013)... , May 21, 2013  MacroGenics, Inc. ... study of margetuximab (MGAH22), an Fc-modified chimeric monoclonal ... expressing the HER2 oncoprotein," will be presented at ... of Clinical Oncology during the Developmental Therapeutics - ... at 4:15 – 4:30 PM.  The presentation will ...
Breaking Biology Technology:CLD Integrates Tin CAN API with its eLearning Solutions and Launches its Excelerometer Tracking Statement Dashboard 2CLD Integrates Tin CAN API with its eLearning Solutions and Launches its Excelerometer Tracking Statement Dashboard 3ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials 2ERA-EDTA CONGRESS 2013: Late Breaking Clinical Trials 3The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 2The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 3The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 4The U.S. Biochip Products and Services Market is Expected to Reach USD 4.7 Billion in 2018: Transparency Market Research 5MacroGenics Announces Margetuximab (MGAH22) Phase 1 Data Presentation at ASCO; Initiates Phase 2 Clinical Study to Evaluate Activity of Margetuximab in Patients with Metastatic Breast Cancer 2MacroGenics Announces Margetuximab (MGAH22) Phase 1 Data Presentation at ASCO; Initiates Phase 2 Clinical Study to Evaluate Activity of Margetuximab in Patients with Metastatic Breast Cancer 3
... poised to take their business to the $1 million annual ... prize packages, and business mentoring when the Make Mine ... here May 21. , ,The all-day event, which will take ... to women-owned businesses, including those in the technology and life ...
... Hanlon sees a lot of parallels between riding a motorcycle and ... has skinned his knees attempting to do both. , ,Hanlon will ... during the Wisconsin Alumni Research Foundation's Gilson Series ... managing an emerging-growth company. , ,While he figures to be speaking ...
... capital in more deals in 2006, but the improvement was ... Ernst & Young, LLP and Dow Jones VentureOne ... 2006, including a $12 .5 million round by NimbleGen ... a total of $58.47 million. The total, up from the ...
Cached Biology Technology:Women's entrepreneurial event set for May 21 2Motorcycling entrepreneur to speak in Madison on success, failure, capital 2Motorcycling entrepreneur to speak in Madison on success, failure, capital 3Wisconsin fares slightly better in venture capital chase 2Wisconsin fares slightly better in venture capital chase 3
...
The 12-Tube Magnetic Separation Rack is designed to be used for small-scale separations using magnetic particles. ,Capacity: 12 microcentrifuge tubes. ,Magnets: Neodymium rare earth permanent ma...
Certified U.S. origin. Bovine Serum:, *Certified U.S. origin. Available raw, nonsterile filtered, or sterile filtered. , , *Sterility tested , , *Low Hemoglobin levels , , *Mycoplasma testing upon...
...
Biology Products: