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Reminding doctors which antibiotics to prescribe cuts C. difficile infection rates

tions to improve prescribing were poor quality unplanned studies with no control groups or outcomes and inadequate statistical analysis," explains Dr Stone.

The authors suggest that wider use of this method to study interventions in other hospitals would enhance the pool of good quality evidence on the best ways to change antibiotic prescribing. It would also enable meaningful comparisons between studies and interventions.

The paper is intended to be an example of best practice for reporting such studies. Guidelines laying out minimum requirements for data recording, statistical analysis, and reporting are contained in the consensus statement for infection control studies---labelled the ORION (Outbreak Reports and Intervention studies Of Nosocomial infection) statement---are being published simultaneously in The Lancet Infectious Diseases this month and also the Journal of Antimicrobial Chemotherapy.4 This statement, put together with the aim of improving the quality of research in hospital epidemiology to ensure it is robust enough to influence policy and practice, is intended to be an equivalent to the CONSORT standards and checklist for reporting of randomized controlled trials.

Dr Stone says: "The quality of research in infection control must be robust enough to influence policy and practice in the fight against hospital acquired infection. This statement is intended to help produce well designed studies that will aid that fight"


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Source:Oxford University Press


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