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Regenerating worms help elucidate stem cell biology

ght about piwi for some time, which is that it was required to maintain the stem cell, we think that's not happening here. The stem cells are being maintained by another mechanism, and it's the division progeny, instead, that is being affected."

There's some evidence, Sánchez Alvarado said, that piwi plays a similar role in regulating the progeny of adult stem cells in humans. He cautioned that more work is needed to determine just how functionally similar the factors regulating stem cells in planaria are to those in higher organisms. But so far there's good evidence that many of the important genes are the same, he said. And the current study begins the detailed analysis that will be needed to establish whether this humble worm can illuminate the mechanisms underlying the unique biology of stem cells.


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Source:Howard Hughes Medical Institute


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The RiboGreen RNA Quantitation Kit is one of the most sensitive detection systems for the quantitation of RNA in solution. The assay is approximately 1000-fold more sensitive than absorbance measure
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Recommend to use at up to 5000X dilutions for cell culture (e.g. Add 1 ul to 1 ml of culture medium.)
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