Navigation Links
Purdue's gold nanorods brighten future for medical imaging

for a type of imaging called "two-photon fluorescence," which provides higher contrast and brighter images than conventional fluorescent imaging methods.

Photons are the individual particles that make up light. In two-photon fluorescence, two photons hit the nanorod at the same time.

Because of the two-photon effect, the method might enable scientists to develop advanced "non-linear optical techniques" that provide better contrast than conventional technologies. Cheng is applying the two-photon fluorescence and other non-linear optical effects to develop imaging methods that provide improved contrast over conventional technologies.

The researchers injected the nanorods into mice and then took images of the tiny structures as the nanorods flowed through blood vessels in the animals' ears. Individual nanorods proved to be 58 times brighter than the two-photon fluorescence from a single rhodamine molecule. Within a half hour after being injected, the nanorods could no longer be observed in the animals' blood, presumably because the rods had been filtered out of the blood by the kidneys.

"To be able to detect cells at an early stage of disease such as cancer, it is important to have a reliable technique that has sensitivity at the single-particle level," Wei said. "The gold nanorods demonstrate that Cheng's nonlinear imaging methods are capable of this level of detection."

The research has been funded by the National Institutes of Health and is affiliated with the Birck Nanotechnology Center and the Bindley Bioscience Center, both in Purdue's Discovery Park, the university's hub for interdisciplinary research.

The research paper was written by Haifeng Wang, a postdoctoral research associate in biomedical engineering; Terry B. Huff, a graduate teaching assistant in chemistry; Daniel A. Zweifel, a graduate student in chemistry; Wei He, a graduate research assistant in chemistry; Low; Wei; and Cheng.


'"/>

Source:Purdue University


Page: 1 2

Related biology news :

1. HIV vaccine trial breaks ground for future research
2. Prozac for future Plants on Mars
3. Plants reveal a secret and bring researchers nearer a cleaner future
4. Report focuses on challenges to unlocking future promise of vaccines
5. Researchers make long DNA wires for future medical and electronic devices
6. New U. of Colorado at Boulder flu chip may help combat future epidemics, pandemics
7. Understanding the oceans microbes is key to the Earths future
8. Tastier tomatoes in the future?
9. Stable polymer nanotubes may have a biotech future
10. Food-crop yields in future greenhouse-gas conditions lower than expected
11. Brighter future for giant panda?
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Purdue gold nanorods brighten future for medical imaging

(Date:5/17/2013)... iCargo project (Intelligent Cargo in Efficient and Sustainable Global ... to an improvement in the efficiency of intermodal loading ... decision making. It comprises 29 European organisations with experience ... It has a budget totalling 17,000,000 and a duration ... working to specify and develop the semantic components and ...
(Date:5/17/2013)... Bethesda, MD The Federation of American Societies for ... of National Institutes of Health (NIH) funding trends highlighting ... to support critical research. The FASEB analysis follows a ... Francis Collins, MD, PhD, who testified that the $1.6 ... to sequestration is "having a substantial impact on the ...
(Date:5/16/2013)... Illustrating a commitment to the support of ... (AGA) Research Foundation has announced the inaugural AGA ... recipients. Supported by the National Institute of Diabetes ... award helps underrepresented minority students to further their ... , "By establishing this new award, AGA demonstrates ...
Breaking Biology News(10 mins):New logistics services that will cut energy consumption and CO2 emissions 2Underrepresented minority students receive fellowships in digestive disease and nutrition research 2
... tell no tales has long been disproved by archaeology. ... to new heights. In a study that promises fresh and ... New World, a team or researchers from the University of ... the teeth of crew members Christopher Columbus left on the ...
... is gone -- not just over the poles, but everywhere. ... 1980s, is a year-round fixture, with a twin over the ... like Washington, D.C., is strong enough to cause sunburn in ... with likely harmful effects on plants, animals and human skin ...
... insecticide commonly used up until the 1970s may play a ... new study involving several Michigan State University researchers. More ... Lake Michigan were studied for their exposure to DDE ... choice in this month,s edition of Occupational and Environmental ...
Cached Biology News:Teeth of Columbus' crew flesh out tale of new world discovery 2Teeth of Columbus' crew flesh out tale of new world discovery 3New simulation shows consequences of a world without Earth's natural sunscreen 2New simulation shows consequences of a world without Earth's natural sunscreen 3New simulation shows consequences of a world without Earth's natural sunscreen 4Exposure to insecticide may play role in obesity epidemic among some women 2
(Date:5/17/2013)... ALTO, Calif. , May 17, 2013 /PRNewswire/ ... it has achieved 50% enrollment of the total ... to evaluate the safety and preliminary efficacy of ... Cells) therapy for Knee Osteoarthritis (KOA). To date ... (SAE) reported. The Phase I open ...
(Date:5/17/2013)... 17, 2013  Insero Health, Inc., a company developing ... and related neurological disorders, is today reporting top-line results ... INS001 in patients with drug-resistant epilepsy.  The data are ... (AED) Xll meeting by Dr. Steven Schachter ... Insero,s Scientific Advisory Board.  In this study, INS001 appeared ...
(Date:5/17/2013)... Frederick, MD (PRWEB) May 17, 2013 ... release of ezColony version 4.1, a versatile refinement ... world-class premier software solution, improves its advanced methodical ... animal facilities with ezColony 4.1. The network-based platform ... to conduct effective research. While continuing to emphasize ...
(Date:5/17/2013)... (PRWEB) May 17, 2013 Tooth decay is ... showing active signs of the disease. The World Health Organization ... nearly 100% of adults have cavities. What are the long-term ... is showing a strong connection between the oral bacterial imbalance ... this disease so rampant, yet it is also 100% preventable? ...
Breaking Biology Technology:Cellular Biomedicine Group Achieves 50% Enrollment Milestone in Phase I Clinical Trial for Knee Osteoarthritis 2Insero Health Reports Positive Data on Phase I Trial of Novel Therapy for Drug-resistant Epilepsy 2RURO Introduces ezColony 4.1 – The Versatile Transgenic Animal Colony Management Software 2Seeing the Future: How a Revolutionary New Bacterial Screening Device Can Predict a Patient’s Future for Tooth Decay 2Seeing the Future: How a Revolutionary New Bacterial Screening Device Can Predict a Patient’s Future for Tooth Decay 3
... dr. Stuart Parkin as its first ,distinguished professor, ever. Parkin ... of the IBM Almaden Research Center in the USA. Earlier ... Parkin is an expert in the field of spintronics. , ... international top professor to be appointed to this position for ...
... IDIX ) announced today that it will report,its ... Thursday, October,30, 2008 after the U.S. financial markets close., ... release, Idenix,management will host a conference call at 4:30 ... company,s financial results for the third quarter,of 2008 and ...
... Our Children Foundation,a nonprofit charitable foundation dedicated to ... Administration (FDA) has approved the Orphan,Drug Designation of ... Sarcoma cancer. The efforts to develop this drug ... in private industry and at two,universities., Orphan ...
Cached Biology Technology:FDA Approves Orphan Drug Status for Revolutionary Cancer Drug for Children 2
Mouse/Rat WNK1 Affinity Purified Polyclonal Ab...
... of excess dye terminators, template DNA, primers, ... true sequencing products have proved critical for ... is designed to work with dye terminator ... DYEnamicTM ET. The unique uniformity of the ...
Enodgenous alkaline phosphotase inhibitor. Levamisole solution is supplied in concentrated form (20x). The final concentration of levamisole in the substrate solution will be 1 mM....
uncoupling protein 2 (mitochondrial, proton carrier), mRNA (cDNA clone MGC:19567 IMAGE:4335185), complete cds...
Biology Products: