Navigation Links
Public collections of DNA and RNA sequence reach 100 gigabases

The world's three leading public repositories for DNA and RNA sequence information have reached 100 gigabases [100,000,000,000 bases; the 'letters' of the genetic code] of sequence. Thanks to their data exchange policy, which has paved the way for the global exchange of many types of biological information, the three members of the International Nucleotide Sequence Database Collaboration [INSDC,] - EMBL Bank [Hinxton, UK], GenBank [Bethesda, USA] and the DNA Data Bank of Japan [Mishima, Japan] all reached this milestone together.

Graham Cameron, Associate Director of EMBL's European Bioinformatics Institute, says "This is an important milestone in the history of the nucleotide sequence databases. From the first EMBL Data Library entry made available in 1982 to today's provision of over 55 million sequence entries from at least 200,000 different organisms, these resources have anticipated the needs of molecular biologists and addressed them - often in the face of a serious lack of resources."

David Lipman, Director of the National Center for Biotechnology Information, adds: "Today's nucleotide sequence databases allow researchers to share completed genomes, the genetic make-up of entire ecosystems, and sequences associated with patents. The INSDC has realized the vision of the researchers who initiated the sequence database projects, by making the global sharing of nucleotide sequence information possible."

Takashi Gojobori, Director of the Center for Information Biology and DNA Data Bank of Japan, says: "The INSDC has laid the foundations for the exchange of many types of biological information. As we enter the era of systems biology and researchers begin to exchange complex types of information, such as the results of experiments that measure the activities of thousands of genes, or computational models of entire processes, it is important to celebrate the achievements of the three databases that pioneered the open exchange of biological information."

In the late 1970s, as researchers started to study organisms at the level of their genetic code, several groups began to explore the possibility of developing a public repository for sequence information. In the early 1980s this led to the launch of two databases: the first was the EMBL Data Library, based at the European Molecular Biology Laboratory [EMBL] in Heidelberg, Germany [the Data Library is now known as EMBL Bank and is based at EMBL's European Bioinformatics Institute, Hinxton, UK]. Hot on its heels came GenBank, initially hosted by the Los Alamos National Laboratory [LANL] and now based at the National Center for Biotechnology Information, Bethesda, MD, USA. Both of these databases were seeded by collections begun by far-sighted individuals: EMBL Bank by the collection of Kurt Stuber, then based at the University of Cologne in Germany, and GenBank by the collection of Walter Goad at LANL. The two nascent databases began collaborating very early on, an interaction that was initiated by Greg Hamm, the EMBL Data Library's first employee. Staff at the two databases, which at that time had to find sequences in published journal articles and re-key them into the databases, allocated journals to each team to avoid duplication of effort, and began the arduous task of mapping the fields from one database onto those of the other so that they could exchange information. By the time the International Nucleotide Sequence Consortium became formalized in February 1987, a third partner, the DNA Data Bank of Japan, had been launched at the National Institute of Genetics in Mishima, and collaborated with its European and US counterparts right from the start.

Much has changed since the days when sequences were manually keyed in from the literature or sent on floppy disc and distributed to users on 9-track magnetic tapes, but the purpose of the databases - to make every nucleotide sequence in the public domain freely available to the scientific community as rapidly as possible - remains as strong now as it was in the beginning.


Source:European Molecular Biology Laboratory

Related biology news :

1. NIH Calls on Scientists to Speed Public Release of Research Publications
2. AIDS Public Awareness Campaign Expands Following Report Of Rapidly Progressive HIV
3. Public release of pig genomic sequences
4. PLoS ONE is launched by the Public Library of Science
5. Public Library of Science to launch new, open access journal on neglected tropical diseases
6. Mailman School of Public Health researchers report blood DNA can be early predictor of liver cancer
7. Viral DNA sequence a possible trigger for breast cancer
8. GATA: a graphic alignment tool for comparative sequence analysis
9. Found: Missing sequence of the human Y chromosome
10. Researchers uncover sequence of major rice pathogen
11. Agilent Technologies releases probe sequence, annotation information for all its commercial gene expression microarrays
Post Your Comments:

(Date:10/29/2015)... Calif. , Oct. 29, 2015  The J. ... new report titled, "DNA Synthesis and Biosecurity: Lessons Learned ... the Department of Health and Human Services guidance for ... in 2010. --> ... it also has the potential to pose unique biosecurity ...
(Date:10/29/2015)... NXTD ) ("NXT-ID" or ... the growing mobile commerce market and creator of ... leading marketplace to discover and buy innovative technology ... on StackSocial for this holiday season.   ... a biometric authentication company focused on the growing ...
(Date:10/27/2015)... SAN JOSE, Calif. , Oct. 27, 2015 /PRNewswire/ ... human interface solutions, today announced that Google has adopted ... family of touch controller solutions to power its newest ... Nexus 6P by Huawei. --> ... ecosystem partners like Google to provide strategic collaboration in ...
Breaking Biology News(10 mins):
(Date:11/24/2015)... ... 2015 , ... InSphero AG, the leading supplier of easy-to-use solutions for production, ... to serve as Chief Operating Officer. , Having joined InSphero in November ... and was promoted to Head of InSphero Diagnostics in 2014. There she has ...
(Date:11/24/2015)... HemoShear Therapeutics, LLC, a privately held ... disorders, announced today the appointment of H. ... (BOD). Mr. Watkins is the former president and ... and also served as the chairman of the ... Chairman and CEO of HemoShear Therapeutics. "The combination ...
(Date:11/24/2015)... Nov. 24, 2015 According to two new studies, ... This is something that many doctors, scientists, and public health ... remains: with fewer PSA tests being done, will there be ... Dr. David Samadi, "Despite the efforts made in ... the second leading cancer cause of death in men, killing ...
(Date:11/23/2015)... ... November 23, 2015 , ... Shimadzu Corporation ... its Nexera UC Unified Chromatography system. The award from R&D magazine recognizes Shimadzu’s ... of the year in the analytical and testing category. R&D Magazine chose the ...
Breaking Biology Technology: