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Psst! Coffee drinkers: Fruit flies have something to tell you about caffeine

icates that flies have different receptors for the response to other types of bitter compounds," he says.

"We also tested whether the flies avoided the related bitter compounds found in tea and cocoa -- chocolate -- and found that Gr66a also is required for the response to the compound in tea, but not for the one in chocolate," he says.

Fruit flies often are used as experimental organisms because they grow quickly and are easy to manipulate genetically. Now that Montell and his colleagues have a mutant fly that is unable to taste caffeine, they hope to further examine the other genes and molecules involved in the caffeine response and better understand the biochemistry behind caffeine-induced behavior in other organisms, namely humans.


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Source:Johns Hopkins Medical Institutions


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