Navigation Links
Protein offers way to stop microscopic parasites in their tracks

Scientists may have found a way to throw a wrench in the transmissions of several speed demons of the parasite world. Researchers at Washington University School of Medicine in St. Louis and Harvard University have identified a protein that could help them develop drugs to stop or slow cell invasion by malaria and other parasites known as apicomplexans.

Results of the study will appear in the March 15 issue of Proceedings of the National Academy of Sciences. Scientists identified the new protein in the protozoan parasite Toxoplasma, which epidemiologists estimate infects 25 percent of all humans. The parasite rarely causes symptoms in most people, but can become a potentially life-threatening infection when the immune system is weakened by illnesses such as HIV or is suppressed to facilitate an organ transplant.

"Toxoplasma is like a time bomb that can go off and cause serious trouble when the immune system wanes or is compromised," explains L. David Sibley, Ph.D., professor of molecular microbiology at Washington University School of Medicine. For the study, researchers in Sibley's lab collaborated with Sinisa Urban, Ph.D., assistant professor of microbiology at Harvard University.

Sibley's lab studies Toxoplasma both because of the threat it poses to patients and for the potential insights it can offer into other apicomplexan parasites, which include malaria and Cryptosporidium. Malaria, which is spread by mosquito bites, kills at least 1 million people per year through damage to red blood cells and clogging of the capillaries that feed the brain and other organs. Cryptosporidium, which causes diarrhea, vomiting and other symptoms, is one of the most common causes of water-borne disease in the world.

"These other parasites are more devastating in terms of the number of people they affect, but they're somewhat harder to work on," Sibley explains. "Because it's so much easier to study, we use Toxoplasma as a way to ask about very basic
'"/>

Source:Washington University in St. Louis


Page: 1 2 3

Related biology news :

1. Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
2. Protein discovery could unlock the secret to better TB treatment
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. An HIV Protein Plays a Surprising Role in Gene Activation
5. Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
6. New SARS Protein Linked To Important Cell Doorway
7. The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures
8. PANTHER Protein Classification System Database 5.0
9. Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimers, Parkinsons Disease
10. Newly Discovered Compound Blocks Known Cancer-Causing Protein
11. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Protein offers way stop microscopic parasites their tracks

(Date:4/10/2015)... , April 10, 2015 Research ... of the "Security Competitive Profiles - NEC" ... , NEC will continue to supply a ... the market, with a company focus on the development ... Winning opportunities in the Asia-Pacific ...
(Date:4/2/2015)... , April 2, 2015 ... tests DERMALOG by far outperforms the strongest competitors, ... maintaining high accuracy, the system is capable of ... the speed proves up to be ten times ... than its runner-up performance.      (Photo: ...
(Date:4/1/2015)... , Apr. 1, 2015  NXT-ID, Inc. (NASDAQ: ... company focused on the growing mobile commerce market, announces ... smart wallets is underway to early access pre-order customers. ... includes usage at retail outlets including Walmart, Target, AT&T, ... report Wocket was accepted at all outlets and very ...
Breaking Biology News(10 mins):NEC Security Competitive Profile 2015 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 2NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 3NXT-ID Reports Second Shipment of Wocket Smart Wallets Underway to Early Access Pre-order Customers and Provides User Feedback 4
... and Agriculture (NIFA) today announced $24 million in grants ... The agriculture animal industry plays a crucial role in ... for 42 percent of forecast U.S. agricultural receipts in ... from animal diseases, reduced fertility, low nutrition and growth ...
... of Medicine and Science is investigating the potential use of ... Dr. Mamdooh Ghoneum presented his findings Tuesday, Feb. 2 ... the American Association for Cancer Research (AACR) at the Omni ... focus of the meeting is cell death regulation and how ...
... University of Oklahoma Health and Exercise Science Department has ... 20-minute walk, according to Joel T. Cramer, assistant professor ... contracted with OU to test the weight-loss benefits of ... black pepper, caffeine and a concentrated form of capsaicinthe ...
Cached Biology News:NIFA awards funding for animal health and production research 2NIFA awards funding for animal health and production research 3NIFA awards funding for animal health and production research 4Charles Drew cancer studies with yeast yield excellent results 2
(Date:5/4/2015)... May 4, 2015   Intrexon Corporation (NYSE: ... quarter 2015 financial results after the market closes on ... call that day at 5:30 PM ET to discuss ... The conference call may be accessed by dialing ... join the "Intrexon Conference Call."  Participants may also access ...
(Date:5/4/2015)... 2015 Marianjoy Rehabilitation Hospital ... arm and hand impairments by acquiring the Armeo®Spring ... Terrace network site. , Secured through grant support ... highly-regarded treatment option for patients with upper extremity ... becomes one of just four Illinois providers offering ...
(Date:5/1/2015)... OncoTAb, Inc., a University of ... that Pinku Mukherjee, Ph.D. has received the O. ... highest faculty honor. Mukherjee received the award, which recognizes ... innovative research and development of cancer diagnostics and treatments. ... moment in my scientific career,” said Mukherjee, OncoTAb Co-founder ...
(Date:5/1/2015)... May 1, 2015 Pfenex Inc. (NYSE ... the development of biosimilar therapeutics including high value ... its first quarter 2015 financial results will be ... open of market. At 8:30 am Eastern Time, Pfenex ... the financial results and provide a business update. A ...
Breaking Biology Technology:Intrexon to Announce First Quarter 2015 Financial Results on Monday, May 11, 2015 2Marianjoy Acquires Armeo®Spring Arm and Hand Rehabilitation Exoskeleton at Oakbrook Terrace Facility 2OncoTAb CSO Awarded the University of North Carolina’s O. Max Gardner Award 2Pfenex To Report First Quarter 2015 Results and Provide Business Update on Thursday, May 14, 2015 2
... Feb. 5 Memory Pharmaceuticals,Corp. (Nasdaq: MEMY ... Chief,Executive Officer, will provide a company update at ... Tuesday, February 12, 2008 at 10:15 a.m. ET ... Interested parties may access the live webcast of ...
... 5 ViroPharma Incorporated,(Nasdaq: VPHM ) today ... operating officer of ViroPharma, will present at the ... on Monday, February 11, 2008. The,conference is being ... ViroPharma,s presentation will be webcast live for investors ...
... Feb. 5 Physicians Reference,Laboratory ("PRL") announced today that ... to date. Under the marketed,name COMPLeTe Care HPV, the ... high risk types of HPV which can lead to,cervical ... common form of female,cancer with an incidence of over ...
Cached Biology Technology:Physicians Reference Laboratory Announces New Diagnostic for Women's Health 2
These 18x18 square No.1 Corning cover glasses are made from No. 0211 zinc titania glass and are 0.16 to 0.19mm thick....
... filters suitable for use in the Microsart e.motion ... each filter, in a specially designed individual package ... of the band of membrane filter units ensures ... shape of the sealed band guarantees uniform dispensing ...
...
These 22x40mm rectangular No.1 Corning cover glasses are made from No. 0211 zinc titania glass and are 0.16 to 0.19mm thick. • Approx. Pcs Oz : 73...
Biology Products: