Navigation Links
Protein 'nanosprings' most resilient found in nature

A component of many proteins has been found to constitute one of the most powerful and resilient molecular "springs" in nature, researchers have discovered. The engineers and biologists from Duke University and the Howard Hughes Medical Institute say their discovery could lead to a new understanding of mechanical processes within the living cell. The discovery also could provide potent nanoscale "shock absorbers" or "gate-opening springs" in tiny nanomachines.

The team's findings were published in an advanced online publication of Nature on Jan. 15, 2006.

The finding that the protein components, called "ankyrin repeats," exhibit such unprecedented elastic properties could lead to a new understanding of how organisms, including humans, sense and respond to physical forces at the cellular level, the researchers said. The nanometer-sized springs are also ideal candidates for building biologically-inspired springy nanostructures and nanomaterials with an inherent ability to self-repair, they reported. A nanometer is one billionth of a meter.

"Whereas other known proteins can act like floppy springs, ankyrin molecules behave more like steel," said Piotr Marszalek, professor of mechanical engineering and materials science at the Duke Pratt School of Engineering. "After repeated stretching, the molecules immediately refold themselves, retaining their shape and strength."

"The fully extended molecules not only bounce back to their original shape in real time, but they also generate force in the process of this rapid refolding ?something that had never been seen before," added HHMI investigator Vann Bennett, professor of cell biology at Duke University Medical Center. "It's the equivalent of un-boiling an egg."

Marszalek and Bennett are participants in the Duke University Center for Biologically Inspired Materials and Material Systems. The research was supported by Duke University and the National Science Foundation.

Ankyrin
'"/>

Source:Duke University


Page: 1 2 3 4

Related biology news :

1. Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants
2. Protein discovery could unlock the secret to better TB treatment
3. Researchers Uncover Key Step In Manufacture of Memory Protein
4. An HIV Protein Plays a Surprising Role in Gene Activation
5. Protein Packages Found To Activate Genes; May Be What Regulates Development And Disease
6. New SARS Protein Linked To Important Cell Doorway
7. The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures
8. PANTHER Protein Classification System Database 5.0
9. Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimers, Parkinsons Disease
10. Newly Discovered Compound Blocks Known Cancer-Causing Protein
11. UF Researchers Map Bacterial Proteins That Cause Tooth Loss
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Protein nanosprings most resilient found nature

(Date:9/30/2014)... runoff in Hawaii is causing tumors in endangered sea ... published Tuesday in the peer-reviewed open-access journal PeerJ ... in algae that the turtles eat, promoting the formation ... organs. , Scientists at Duke University, the University of ... conducted the study to better understand the causes ...
(Date:9/30/2014)... Ludwig-Maximilians-Universitaet (LMU) in Munich report that a new ... sensitive to chemotherapeutic drugs. They have also pinpointed ... target for anti-tumor agents. , Researchers led ... Sieber of the Technische Universitt Mnchen have identified ... new weapon in the fight against malignant tumors. ...
(Date:9/30/2014)... with IVF? Here,s some hope: A new research report ... FASEB Journal , explains how scientists developed a ... which induced embryo development in human and mouse eggs ... the sperm cell during fertilization. , "We believe that ... shift in our understanding of human fertilization by providing ...
Breaking Biology News(10 mins):Pollution linked to lethal sea turtle tumors 2Pollution linked to lethal sea turtle tumors 3Cancer therapy: Driving cancer cells to suicide 2Synthetic sperm protein raises the chance for successful in vitro fertilization 2
... significantly advance our understanding of the genetic basis of ... past year. They are the users of a web-based ... McGill School of Computer Science and collaborator Mathieu Blanchette. ... contribute to scientific research by arranging multiple sequences of ...
... fruit flies use to sense heat and chemicals may someday ... mosquitoes. , In the current issue of Nature , ... at Brandeis University and his team, spearheaded by KyeongJin Kang ... flies distinguish the warmth of a summer day from the ...
... 2011   Security Management Systems (SMS) , a ... an advanced data center security system for Oracle ... Services Corporation. Based in Somerset, New ... providing Oracle-based business operations solutions and information systems, ...
Cached Biology News:Video game players advancing genetic research 2Addressing pain and disease on the fly 2Security Management Systems (SMS) Completes Oracle Data Center Security Project for Core Services Corporation 2Security Management Systems (SMS) Completes Oracle Data Center Security Project for Core Services Corporation 3
(Date:10/1/2014)... Calif. (PRWEB) September 30, 2014 ... the initial round of grants for the Brain ... undertaking that aims to develop and revolutionize new ... functions of the human brain. This first round ... fiscal year 2014 was allocated to more than ...
(Date:10/1/2014)... VA (PRWEB) October 01, 2014 ... Diagnostic, Clinical Therapeutics, Healthcare IT, and Laboratory Testing industries, ... regulatory positions at the director level and above from ... struggling to stay on top of rapid breakthroughs in ... result, many diagnostic companies have been forced to fold, ...
(Date:10/1/2014)... Industry leaders from retail pharmacies to ... theme, ,Commercial Opportunities in the Era of Reform, from ... Elsevier , a world-leading provider of scientific, technical and ... of some of the industry,s most prominent healthcare leaders ... in the future. The Elsevier Healthcare and ...
(Date:9/30/2014)... AMHERST, Mass. Using a bio-mimicking analog of ... of grass, an international research team led by ... has taken a major step in developing long-sought ... to electricity for use in electronic devices. ... UMass Amherst and others at Stanford University and ...
Breaking Biology Technology:NIH Awards 15 Grants to CHI Members for BRAIN Initiative Research 2NIH Awards 15 Grants to CHI Members for BRAIN Initiative Research 3Slone Partners Meets Growing Demand as Industry Focuses on Reimbursement & Regulation 2Elsevier Healthcare and Pharmaceutical Economics Conference 2014 To Convene Industry Leaders to Discuss Top Healthcare Business Issues 2Elsevier Healthcare and Pharmaceutical Economics Conference 2014 To Convene Industry Leaders to Discuss Top Healthcare Business Issues 3Blades of grass inspire advance in organic solar cells 2Blades of grass inspire advance in organic solar cells 3
... LI-COR(R) Biosciences announces,an enhanced matching funds ... $1.75 million in matching funds is available ... each qualifying institution. The,Genomics Education Matching Funds ... to help colleges acquire LI-COR DNA sequencing ...
... PharmBIO Products Launches Unique Online Configurator For the ... ... Gore PharmBIO Products has,launched an industry first -- an ... configuring fluid,assemblies for biopharmaceutical manufacturers., The GORE(TM) STA-PURE(SM) Bioprocess ...
... support advancement to Phase 2 -, - Results of ... BRISBANE, Calif., Sept. 24 InterMune, Inc.,(Nasdaq: ... and,in-vitro studies of ITMN-191 (R7227) accepted for presentation at ... Study of Liver Diseases,(AASLD, Oct. 31 - Nov. 4 ...
Cached Biology Technology:Gore's Legacy of Innovation Extends From Products to Processes 2Gore's Legacy of Innovation Extends From Products to Processes 3InterMune to Present Four Abstracts on HCV Protease Inhibitor ITMN-191 at the AASLD Meeting 2InterMune to Present Four Abstracts on HCV Protease Inhibitor ITMN-191 at the AASLD Meeting 3InterMune to Present Four Abstracts on HCV Protease Inhibitor ITMN-191 at the AASLD Meeting 4InterMune to Present Four Abstracts on HCV Protease Inhibitor ITMN-191 at the AASLD Meeting 5InterMune to Present Four Abstracts on HCV Protease Inhibitor ITMN-191 at the AASLD Meeting 6
... temperature control for microbiology and cell culture. ... is suitable for DASGIP bioreactors from 150 ... temperature ranges from approximately 10 °C to ... with an individual electrical heating element with ...
... gel stain is a sensitive nucleic acid ... to RNA and low background in gels, making ... polyacrylamide gels using laser scanners or standard UV ... mL unit size (S-7568) and a special packaging ...
... reports the data from any one of IITC ... recorder. The final data is sent from the ... is automatic for Systolic, Mean, Heart Rate while ... is always in the position to override the ...
Sirtuin 7 (SIRT7) Rabbit anti-Human Polyclonal Antibody Immunogen: Synthetic peptide - KLH conjugated Family: Other Recommended Storage: Long term: -20C; Short term: +4C...
Biology Products: