Navigation Links
Protein-coated dental implants could improve bone regeneration

to the mineral component of bone, may actually interfere with regeneration," Dr. Wikesjö says. "They may not resorb quickly enough and may block the space for new tissue to grow into."

The experiments helped researchers narrow down possible treatments to the use of proteins that directed stem cells to become bone-forming cells. Those proteins ?called bone morpheonetic proteins ?have already shown promise as a regeneration therapy for craniofacial reconstruction.

"None of us had any idea at the time how or if those proteins could be useful in treating tooth loss," Dr. Wikesjö says.

To find out, researchers placed the proteins around teeth and implants in animal models.

Around teeth, the bone-forming cells grew into existing bone and eventually morphed into bone themselves. However, the root of the tooth was destroyed by the replacement bone. That process impeded regeneration of other essential tissues around the tooth.

Applying the protein to implants proved more beneficial.

"There was almost complete regeneration," he says. "The generated bone bonded with the implant's surface and, eventually, existing bone in the gums. That allowed for the regeneration of gum tissues."

The next step is clinical trials of an implant coated with the proteins, which Dr. Wikesjö hopes to start this summer.

"There are still things we need to learn. In some cases, the protein may rapidly release from the implant, and other times, there appears to be a more gradual release," Dr. Wikesjö says. "We need to find out what factors cause that. In the end, we may not need to use much protein to make the implant effective. Those are things we're looking at now."


'"/>

Source:Medical College of Georgia


Page: 1 2

Related biology news :

1. Oldest cranial, dental and postcranial fossils of early modern European humans confirmed
2. Give thanks for the cranberry, say dental researchers
3. Scientists re-grow dental enamel from cultured cells
4. Bacteria from patients dental plaque causes ventilator-associated pneumonia
5. Using dental X-rays to detect osteoporosis
6. Engineers improve plastics potential for use in implants by linking it to biological material
7. Innovative coating could give medical implants a longer life
8. Sooner is better with cochlear implants, Stanford scientist shows
9. Breast implants not associated with cancer risk, study reports
10. With cochlear implants, earlier use leads to better speech
11. Nanotechnology being used to improve biocompatibility of human prosthetics and implants
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Protein coated dental implants could improve bone regeneration

(Date:10/15/2014)... University Mainz (JGU) as a full member, ensuring ... a significant nationwide standing in the field of ... Gutenberg University Mainz as a full member of ... and international competition for the best minds and ... proud that Mainz University has been recognized as ...
(Date:10/15/2014)... Fred Alt will be awarded the 44th Rosenstiel Award ... for his pioneering research exploring the mechanisms of genomic ... cancer cells. Alt is the second alumnus to win ... Nobel Prize in 2003. , Alt is the Charles ... at Harvard Medical School and an investigator at the ...
(Date:10/14/2014)... 2014)—It,s been millions of years since T. rex ... by Ohio University scientists is breathing life back into ... dinosaur snouts. The research has important implications for how ... to enhance the sense of smell and cool their ... Ohio University doctoral student Jason Bourke, lead author of ...
Breaking Biology News(10 mins):Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 2Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 3Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 3
... Lysmata amboinensis usually live in monogamous pairs, but dark ... Central,s open access journal Frontiers in Zoology shows ... attack and kill each other until only a single pair ... This means that they start out as males but, as ...
... pollination, the number of seeds they produce, or their relative ... of pollen. The number of visits a plant may receive ... plant density. But what if a plant happens to grow ... pollinators visiting its flowers? Will all the effort put into ...
... and depth of the Deepwater Horizon oil spill ... severity of ecological damage and to develop restoration plans for ... report by the National Research Council. A broad approach ... production -- in addition to replacing natural resources damaged by ...
Cached Biology News:Violent passions jealous cleaner shrimp murder their rivals 2How does a plant survive with few mates or pollinators? A European herb has figured out its own way 2How does a plant survive with few mates or pollinators? A European herb has figured out its own way 3New report offers broad approach to assessing impacts of ecological damage 2New report offers broad approach to assessing impacts of ecological damage 3
(Date:10/22/2014)... 22, 2014 Nuvilex, Inc. (OTCQB: NVLX) – ... people worldwide are living with diabetes, with  that number ... The global market for diabetes treatments is approximately $500 ... worldwide died from pancreatic cancer.  Pancreatic cancer is the ... in the United States , and ...
(Date:10/20/2014)... YORK , Oct. 20, 2014 ... their experimental ZMapp™ antibody therapeutic to fight the ... how difficult and time-consuming the production of pharmaceuticals ... market research publisher said that while some may ... of this compound, those with industry knowledge are ...
(Date:10/20/2014)... 20, 2014 , A major ... and the delivery of care has revealed changing trends ... inequalities in the provision of healthcare services across the ... by United European Gastroenterology (UEG), have been announced today ... awareness of the burden of GI disorders across ...
(Date:10/20/2014)... 2014 Earle Martin , ... today that Ellen Teplitzky, an experienced attorney specializing ... pharmaceutical industry, has joined the firm as Director ... services practice. NDA Partners provides legal services, ... testimony, to top law firms and their clients ...
Breaking Biology Technology:Nuvilex Brief Analyst Report: Thinking Outside the Box by BrokerBank Securities, Inc. 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5NDA Partners Appoints Ellen Teplitzky, JD as Director of its Legal Services Practice 2
... March 14 GHI Medical, a national,leader in ... to,correlate the results of a current test used ... is called the TrichoBioScan(TM)., The TrichoBioScan(TM) consists ... with an in-depth microscopic analysis of a person,s,hair ...
... 14 ,Renovis, Inc. (Nasdaq: RNVS ), a biopharmaceutical ... major medical needs in the areas of,neurological and inflammatory ... year ended December 31, 2007., Revenue for the ... was,$1.3 million and $9.8 million, respectively, compared to $2.2 ...
... Diagnostics,Incorporated (NYSE: DGX ), the nation,s leading ... it is scheduled to speak,at the Lehman Brothers ... 2008, at The Loews Miami Beach Hotel, Miami, ... at 9:00 a.m.,Eastern Time., The presentation will ...
Cached Biology Technology:Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 2Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 3Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 4Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 5Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 6Renovis Reports Fourth Quarter and Full Year 2007 Financial Results 7Quest Diagnostics to Speak at Lehman Brothers 11th Annual Global Healthcare Conference 2
BD BioCoat Collagen IV 35 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of mouse collagen type IV....
... are designed for sequencing inserts cloned into ... or T3 RNA polymerase promoters, or lambda ... at a concentration of 0.1 µg/µl in ... DNA sequencing reactions using SequiTherm™ EXCEL™ II ...
BD BioCoat Matrigel Matrix 35 mm Culture Dishes Coating : BD MatrigelTM Basement Membrane Matrix ,Surface : ECM/attachment factors ,Surface area : 9.6 cm2 ,Dim nominal : 35 mm x 10 mm ,Vo...
BD BioCoat Collagen I 35 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of rat tail collagen type I....
Biology Products: