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Protein That Promotes Survival Of Stem Cells Might Be Key To Poor Leukemia Prognosis

lly, the investigators showed that growth factors (natural proteins that stimulate cells to grow), such as the "stem cell factor," trigger the expression of the Mcl-1 gene. This was an important clue to how cells control the powerful effects of Mcl-1.

Other authors of this study are Hiromi Iwasaki, Christy C. Ong, Heikyung Suh, Shin-ichi Mizuno, Koichi Akashi and Stanley J. Korsmeyer (Dana-Farber Cancer Institute).


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Source:St. Jude Children's Research Hospital


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