Navigation Links
Promising new West Nile therapy cures disease in mice

treatment--known as a monoclonal antibody--after finding that antibodies taken from the blood of people who recovered from West Nile fever could cure mice infected with West Nile virus. But antibodies derived from human blood have potential disadvantages: they vary in their ability to fight the disease, and although all precautions are taken to purify the antibodies, the blood might harbor other potentially dangerous infectious agents.

The Washington University scientists made 46 monoclonal antibodies against West Nile virus and then eliminated the less effective ones through a tedious molecular-level screening process. They then turned to Rockville, MD-based MacroGenics Inc., to create a human-like version of the most effective antibody. MacroGenics stitched the part of the antibody that cripples the West Nile virus into the scaffold of a human antibody. The monoclonal antibody was several hundred times more potent in cell culture tests than antibodies obtained from people who had recovered from West Nile virus infection.


'"/>

Source:NIH


Page: 1 2

Related biology news :

1. Another Look Finds Promising Proteomics Test is Not Biologically Plausible
2. Promising therapies for haemophilia & heart disease
3. Promising cell protein may play role in infection and dry eye
4. Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
5. Columbia research lifts major hurdle to gene therapy for cancer
6. Combination therapy boosts effectiveness of telomere-directed cancer cell death
7. Gene therapy converts dead bone graft to new, living tissue
8. Study identifies predictors of HIV drug resistance in patients beginning triple therapy
9. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
10. Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
11. New therapy for HIV/AIDS eliminates needles and excessive toxicity
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Promising new West Nile therapy cures disease mice

(Date:7/27/2014)... Barts Cancer Institute have found that targeting a molecule ... effective, according to research published in Nature ... of Queen Mary University of London, have found that ... body to repair itself after chemotherapy or radiotherapy, which ... removed FAK from blood vessels that grew in melanoma ...
(Date:7/25/2014)... burn scars on this false-color image from the Terra satellite ... year,s rash of wildfires in Eastern Russia. The burn ... green background. The wildfires have broken across the remote ... in this false-color image from the MODIS instrument, it ... fires that continue. Two recent image features noted below show ...
(Date:7/25/2014)... Birla, associate professor of biomedical engineering at the ... on tissue engineering and artificial organ development., "Introduction ... comprehensive guide to entering into the field of ... professor of biomedical engineering at UH, served as ... that while there are other published books on ...
Breaking Biology News(10 mins):New drug target can break down cancer's barrier against treatment 2University of Houston researcher publishes textbook on tissue engineering 2
... be discussed at the forthcoming UN climate conference in ... some species from extinction but inadvertently increase the risk ... of the world,s top tropical forest scientists, coordinated by ... of carbon-rich tropical forests will help reduce climate change ...
... but when they,re potted with strangers of the same species ... reveals. The research, which appears in the current issue ... plants will not only compete underground for soil nutrients, but ... the ongoing struggle for light. It follows previous research ...
... scientists has developed a new approach to studying how immune ... described in the November 15 issue of Nature Methods ... bodies they secrete molecules, leaving behind chemical trails as they ... time that immune cells follow these trails in order to ...
Cached Biology News:New climate treaty could put species at risk 2Plants prefer their kin, but crowd out competition when sharing a pot with strangers 2Scientists guide immune cells with light and microparticles 2
(Date:7/25/2014)... July 25, 2014 Research and ... "Global Metabolomics Market 2014-2018" report to their ... Metabolomics or Metabonomics is the scientific ... become a new experimental technique that is being ... sciences. Metabolites are small molecules that are present ...
(Date:7/25/2014)... 2014  Galmed Pharmaceuticals Ltd. (Nasdaq: GLMD ... development and commercialization of a once-daily, oral therapy for ... announced financial results for the period ended June 30, ... , Reported cash and cash equivalents totaling $37.4 million ... 31, 2013.  , Reported a net loss of ...
(Date:7/24/2014)... A novel combination of microscopy and data processing has ... National Laboratory an unprecedented look at the surface of ... properties. , The research team led by ORNL,s ... a perovskite manganite, a complex material that exhibits dramatic ... surface behavior could benefit researchers who are interested in ...
(Date:7/24/2014)... on sophisticated equipment, trained personnel, and detection dogs ... terrorist attacks. A revolutionary new electronic chip with ... job much easier. , The groundbreaking nanotechnology-inspired sensor, ... University ,s School of Chemistry and Center for ... company Tracense, picks up the scent of explosives ...
Breaking Biology Technology:Global Metabolomics Market 2014-2018: Key Vendors are Agilent, Bio-Rad, Bruker, Human Metabolome and Metabolon 2Galmed Pharmaceuticals Reports First Half 2014 Financial Results 2Galmed Pharmaceuticals Reports First Half 2014 Financial Results 3Galmed Pharmaceuticals Reports First Half 2014 Financial Results 4Galmed Pharmaceuticals Reports First Half 2014 Financial Results 5Galmed Pharmaceuticals Reports First Half 2014 Financial Results 6ORNL study reveals new characteristics of complex oxide surfaces 2Nano-sized chip 'sniffs out' explosives far better than trained dogs 2
... This week I spent time with a leading producer of ... The mission find out what aspects of the shopping ... sales representatives make a difference to how much the customer ... experience. , ,Customers were invited to the companys facilities ...
... and Chemicon International, Inc. announced today ... and apply Madison-based Promegas DNA-directed, RNA interference (ddRNAi) ... division of Serologicals Corporation, will have the right ... ddRNAi-based products and reagents for life science research. ...
... focused on the effects of outsourcing technology and offshore ... issue. Whatever the product, there is an effort to ... of this are hurting many aspects of Americans industrial ... making, whether you manufacture low- to high-tech products, maintain ...
Cached Biology Technology:Really Listening to Customers...AND Employees 2Really Listening to Customers...AND Employees 3Offshore outsourcing affects American workers 2Offshore outsourcing affects American workers 3
... polyclonal to BRF2 Immunogen Synthetic peptide: ... of Human BRF2. Reactivity / Specificity ... species. Background Information BRF2 is one ... III transcription factor complex required for transcription of ...
... Antibody - Red, 20X ... antibody at 20X concentration for use ... assays. Quality Assurance ... FarRed fluorescence polarization assays. ...
Kinase Buffer can be used to assay protein kinase activity...
Goat polyclonal to SPFH2 ( Abpromise for all tested applications). Antigen: Synthetic peptide: EDEPLETATKEN, corresponding to C terminal amino acids 328-339 of Human SPFH2 Entrez Gene ID: 11...
Biology Products: