Navigation Links
Procedure predicts embryos most likely to result in pregnancy

To address the high rate of multiple births resulting from in-vitro-fertilization (IVF), researchers at Yale School of Medicine and McGill University have developed a procedure that estimates the reproductive potential of individual embryos, possibly leading to a decrease in multiple-infant births and a higher success rate in women undergoing IVF.

Over 100,000 in-vitro fertilization procedures are performed each year in the United States. In 2002, 3.1 embryos on average were transferred in IVF cycles, but only 34.3 percent resulted in pregnancies. Of those successful pregnancies, 29 percent resulted in multiple births. These statistics remained unchanged within the last decade suggesting that an improvement is needed over the current methodology used for embryo evaluation.

The new procedure will be presented in an abstract at the Society for Gynecologic Investigation Conference in Reno, Nevada on March 16. Emre Seli, M.D., assistant professor in the Yale Department of Obstetrics, Gynecology & Reproductive Sciences led the study.

"The main reason for multiple gestations following in-vitro fertilization is the inability to precisely estimate the reproductive potential of individual embryos," Seli said. "The successes of in-vitro fertilization often result from simultaneous transfer of multiple embryos with the hope that at least one will lead to a pregnancy."

By comparing the content of the successful and unsuccessful embryos, the team established a metabolic profile of embryos that resulted in pregnancies as well as ones that did not.

"We found that proton NMR, a non-invasive nuclear magnetic resonance form of spectroscopy, will determine the metabolic profile of the embryo and accurately predict its reproductive potential," said Seli, who plans to confirm the findings in a larger trial.


'"/>

Source:Yale University


Page: 1

Related biology news :

1. World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics
2. Single-donor Islet Transplantation Procedure Shows Promise For Patients With Type 1 Diabetes
3. Multiple-drug resistant gene expression pattern predicts treatment outcome for pediatric leukemia
4. Ocean climate predicts elk population in Canadian Rockies
5. Identification of specific genes predicts which patients will respond to Hepatitis C treatment
6. Rensselaer researchers develop approach that predicts protein separation behavior
7. Eleven gene signature reliably predicts cancer prognosis
8. Sweet water taste paradoxically predicts sweet taste inhibitors
9. Signature of chromosome instability predicts cancer outcomes
10. Blood test predicts success of quitting smoking using the nicotine patch
11. First-ever genomic test predicts which lung cancer patients need chemotherapy to live
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/4/2017)... April 4, 2017   EyeLock LLC , a ... the United States Patent and Trademark Office (USPTO) has ... the linking of an iris image with a face ... represents the company,s 45 th issued patent. ... very timely given the multi-modal biometric capabilities that have ...
(Date:3/29/2017)...  higi, the health IT company that operates the ... , today announced a Series B investment from ... The new investment and acquisition accelerates higi,s strategy to ... population health activities through the collection and workflow integration ... collects and secures data today on behalf of over ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based and ... 2022", published by MarketsandMarkets, the market is expected to be worth USD 18.98 ... Continue Reading ... ...      ...
Breaking Biology News(10 mins):
(Date:4/28/2017)... ... April 28, 2017 , ... Cynvenio Biosystems, Inc. a leader ... neoadjuvant breast cancer monitoring (NEAT) study in partnership with Allentown, PA-based TME Research ... patients to be monitored over two years with Cynvenio’s ClearID Breast Cancer blood test. ...
(Date:4/27/2017)... and RESEARCH TRIANGLE PARK, N.C. ... (NASDAQ: UTHR ) today announced that its ... $250 million of the company,s common stock. This program ... December 31, 2017. Purchases may be made in the ... transactions from time to time as determined by United ...
(Date:4/27/2017)... ... April 27, 2017 , ... Mitotech S.A, a Luxembourg based ... Optic Neuropathy (LHON) patients. LHON is a rare devastating genetic disease that leads to ... drops in a group of 20 patients carrying 11778, 14484 and 3460 mutations and ...
(Date:4/27/2017)... ... 27, 2017 , ... During the course of this webinar, ... 1,25-Dihydroxyvitamin D can enhance clinical practice. Participants will learn the medical indications and ... Dr. Gregory Plotnikoff, senior consultant with Minnesota Personalized Medicine, will be the speaker ...
Breaking Biology Technology: