Navigation Links
Prenatal exposure to marine toxin causes lasting damage

species called Pseudo-nitzschia. When shellfish and crabs ingest the algae, the toxin can become concentrated in their bodies.

Humans eating contaminated seafood develop symptoms including vomiting nausea, diarrhea and abdominal cramps. In severe cases, the toxin leads to neurological damage, characterized by headaches, confusion, coma and even death. Exposure can also cause amnesic shellfish poisoning, characterized by permanent loss of short-term memory.

Since the discovery of domoic acid on the West Coast, officials there collect regular samples of affected marine animals, including razor clams and Dungeness crabs. Fisheries are closed when domoic acid levels reach 20 parts per million (ppm) in the animals' tissues, the level at which the FDA deems the toxin unsafe for human consumption.

Earlier studies in animals have focused on lethal and highly toxic doses of domoic acid. Such exposures cause extensive damage to the hippocampus, a part of the brain involved in learning and memory. More recent reports examining the effects of a range of doses have found highly reproducible behavioral consequences of sublethal doses of the marine toxin, including impairments to spatial memory.

To explore the toxin's effects during development, the Duke team administered domoic acid to pregnant rats at three levels -- each below those found to cause convulsions or fetal loss. Others animals did not receive the toxin. The researchers then conducted a battery of behavioral tests on the exposed and normal animals to determine the effects of early domoic acid on movement and working memory.

Rats with a history of domoic acid exposure showed greater initial activity in a maze test than control rats, followed by a rapid decline. Moreover, domoic acid exposure affected cognitive function in complex ways, the researchers reported.

Toxin exposure decreased the normal difference between male and female rats in their ability to complete
'"/>

Source:Duke University Medical Center


Page: 1 2 3

Related biology news :

1. Prenatal exposure to famine increases risk of schizophrenia
2. Prenatal nicotine exposure reduces breathing response of newborns...
3. Prenatal cocaines lasting cellular effects
4. Any exposure to tobacco smoke during pregnancy is risky
5. Scalpel-free surgery could reduce risk of HIV and hepatitis exposure for health care workers
6. Experimental vaccine protects nonhuman primates when given after exposure to Marburg virus
7. Nicotine exposure during development leads to hearing problems
8. Bird brains shrink from exposure to contaminants
9. Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax
10. Solvent exposure linked to birth defects in babies of male painters
11. Early exposure to indoor fungus molecules may protect infants against future allergies
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Prenatal exposure marine toxin causes lasting damage

(Date:12/17/2014)... , Dec. 15, 2014 Research and Markets ... addition of the "Samsung Galaxy S5 - ... report to their offering. ... totally different sensing technology than the iPhone 5S, ... sensor in its product. The Galaxy ...
(Date:12/17/2014)... N.C. , Dec. 16, 2014 Valencell, ... licensed its PerformTek biometric technology to industry leaders such ... highly accurate, clinically validated, biometric wearable products. These products ... 6-9 in Las Vegas . ... technology is accurate, flexible and robust – with the ...
(Date:12/15/2014)... --Research and Markets ( http://www.researchandmarkets.com/research/87pph8/global_facial ) ... Facial Recognition Market 2015-2019" report to their ... Facial recognition is a technology used ... measures the overall facial feature of a person ... distance between eyes. Facial recognition is used for ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 2Global Facial Recognition Market 2015-2019: Key Vendors are 3M Cogent, Cognitec Systems, NEC and Safran Group 3
... scientific imagist and researcher at Harvard University,s Initiative ... of the 2007 Lennart Nilsson Award. Frankel was ... of art and crystal-clear scientific illustrations both ... scientific community alike. The Lennart Nilsson Award ...
... United States and Great Britain will speak at The ... and his theory of evolution, which continues to excite ... Darwins death. , The free one-day symposium will be ... 5:00 p.m. at The Field Museums James Simpson Theater. ...
... CA--Industrial fishing operations take plenty of blame for both ... as dolphins, sharks, seabirds, and sea turtles--a phenomenon known ... small-scale Mexican fishery--operated by hand from small open boats--can ... all of the industrial fishing fleets in the North ...
Cached Biology News:Lennart Nilsson Award 2007 2Darwin Symposium at Field Museum offers broad overview of his science and its impact 2Darwin Symposium at Field Museum offers broad overview of his science and its impact 3Small-scale fishing in Mexico rivals industrial fisheries in accidental turtle deaths 2Small-scale fishing in Mexico rivals industrial fisheries in accidental turtle deaths 3
(Date:12/24/2014)... , Dec. 24, 2014  Vermillion, Inc. (Nasdaq: ... gynecologic disease, announced today that the Company closed ... Oracle Investment Management, Jack W. Schuler , ... proceeds were $10.5 million, before offering expenses.  The ... general corporate purposes. Under the terms ...
(Date:12/24/2014)... Missouri (PRWEB) December 23, 2014 GMO ... Swiss biotechnology company, Syngenta, are in the process of ... proceedings. The consolidated case is In Re: Syngenta AG ... U.S. District Court for the District of Kansas. , ... has been handed over to U.S. District Judge John ...
(Date:12/24/2014)... MD (PRWEB) December 23, 2014 ... into law H.R. 83, the Omnibus and Continuing ... first time, made hydrocephalus a condition eligible to ... Programs (CDMRP) administered by the Department of Defense ... with its allies on Capitol Hill, is celebrating ...
(Date:12/24/2014)... Nashville Fertility Center announced that ... the American Society for Reproductive Medicine (ASRM), a leading ... reproductive medicine. In his new role as treasurer, ... board and will have a voice in furthering the ... supported ASRM since 1984 when he joined while conducting ...
Breaking Biology Technology:Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3
... Mass., June 19 Joseph F. Finn, Jr.,C.P.A. ... of ActivBiotics,Inc. ("ActivBiotics") announced today the first distribution ... signifies the substantial,completion of the asset liquidation process ... began the liquidation process, was a transfer,of all ...
... HILLS ESTATES, Calif., June 19 The,Fifth Annual ... for Business Innovation (TCBI), will feature the coming ... and to help manage,diseases. The Conference will take ... 2008. Attendees will include a diverse representation of ...
... supports a multitude of ... threatening situations, PITTSBURGH, June 19 CardiacAssist, ... manufacturers and markets,cardiac assist devices, has announced the ... System. This is indicative of,TandemHeart,s increasing acceptance and ...
Cached Biology Technology:Fifth Annual Healthcare Unbound Conference to Focus on Remote Monitoring, Home Telehealth & eHealth for Disease Management & Wellness Promotion 2Fifth Annual Healthcare Unbound Conference to Focus on Remote Monitoring, Home Telehealth & eHealth for Disease Management & Wellness Promotion 3CardiacAssist, Inc. Surpasses 1300 TandemHeart System Procedures 2
HES-1 [Hairy 1], Available Summer 2003...
E1A (adenovirus early region 1)...
... to Uridine Phosphorylase 1 ( Abpromise ... Antigen: Synthetic peptide: MAATGANAEK AESHNDCPVR LLNPNIAKMK ... corresponding to amino acids 1-99 of Human ... Gene ID: 7378 ...
Nucleobindin 1 [NUCB1]...
Biology Products: