Navigation Links
Prenatal exposure to marine toxin causes lasting damage

Duke University Medical Center researchers have found that the naturally occurring marine toxin domoic acid can cause subtle but lasting cognitive damage in rats exposed to the chemical before birth. Humans can become poisoned by the potentially lethal, algal toxin after eating contaminated shellfish.

The researchers saw behavioral effects of the toxin in animals after prenatal exposure to domoic acid levels below those generally deemed safe for adults, said Edward Levin, Ph.D. Those effects -- including an increased susceptibility to disruptions of memory -- persisted into adulthood, he said.

The findings in rats, therefore, imply that the toxin might negatively affect unborn children at levels that do not cause symptoms in expectant mothers, said Levin. While the researchers note that eating seafood offers significant health benefits, they said their findings suggest that the current threshold of toxin at which affected fisheries are closed should perhaps be lowered. The Federal Drug Administration (FDA) set the current limit based on levels safe for adults, Levin said.

"A single administration of domoic acid to pregnant rats had a lasting affect on the performance of their offspring as adults," Levin said. "The consequences are life-long.

"The findings suggest we may need to re-evaluate monitoring of waters, shellfish and fish to make sure that the most sensitive parts of the human population are protected from toxic exposure to domoic acid," he continued.

The researchers reported their findings in a forthcoming special issue dedicated to research on marine toxins of Neurotoxicology and Teratology.

In 1987, more than 100 people in Canada became ill after eating cultured mussels contaminated with domoic acid. The incident led to three deaths and memory loss in several others.

First detected in the U.S. on the Washington coast in 1991, domoic acid is produced by microscopic algae, specifically the diatom
'"/>

Source:Duke University Medical Center


Page: 1 2 3

Related biology news :

1. Prenatal exposure to famine increases risk of schizophrenia
2. Prenatal nicotine exposure reduces breathing response of newborns...
3. Prenatal cocaines lasting cellular effects
4. Any exposure to tobacco smoke during pregnancy is risky
5. Scalpel-free surgery could reduce risk of HIV and hepatitis exposure for health care workers
6. Experimental vaccine protects nonhuman primates when given after exposure to Marburg virus
7. Nicotine exposure during development leads to hearing problems
8. Bird brains shrink from exposure to contaminants
9. Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax
10. Solvent exposure linked to birth defects in babies of male painters
11. Early exposure to indoor fungus molecules may protect infants against future allergies
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Prenatal exposure marine toxin causes lasting damage

(Date:7/30/2014)... Scientists are searching through a massive collection of ... 50 years ago, and the effort is yielding fresh ... inhabited. , When the collection is fully curated, a ... the largest unbiased Dominican amber collection in the world, ... discovery thus far is that of a pygmy locust, ...
(Date:7/30/2014)... subject of major interest in neuroscience. A large ... distinct stages of Wallerian degeneration: transcription factor activation, ... gene expression responses in the distal segment of ... known, differences in gene expression between the proximal ... and co-workers from Nantong University, China used microarrays ...
(Date:7/30/2014)... analysis of the roughly 3,000 pieces is still in ... the results will be of major significance. "Amazingly often, ... species in Fushun amber that we found in Baltic ... , The Baltic amber comes from the Baltic Sea ... rich in finds are, e.g., the coastal regions of ...
Breaking Biology News(10 mins):Decades-old amber collection offers new views of a lost world 2Chinese mosquitos on the Baltic Sea 2
... invading virus hijacks a cell,s workings by imitating a ... cell signals, the virus destroys a defensive protein designed ... cell cultures, may represent a broader targeting strategy used ... for developing more effective treatments for infectious diseases. ...
... Escherichia coli a bacteria considered the ... is a friend. Cornell University biomolecular engineers have learned ... proteins for making pharmaceuticals cheaper and faster. ( Nature ... Cornell associate professor of chemical and biomolecular engineering, and ...
... (a treatment that involves temporarily inserting and blowing up ... widen it) on veins in the neck and chest ... the venous abnormalities found in those with multiple sclerosis ... the Society of Interventional Radiology,s 37th Annual Scientific Meeting ...
Cached Biology News:To drive infections, a hijacking virus mimics a cell's signaling system 2From scourge to saint: E. coli bacteria becomes a factory - to make cheaper, faster pharmaceuticals 2Interventional radiology: Mitigating symptoms, improving quality of life of MS patients 2Interventional radiology: Mitigating symptoms, improving quality of life of MS patients 3
(Date:7/31/2014)... Boston, MA (PRWEB) July 31, 2014 ... ) finds itself flush with innovative adult stem cell ... patents and has three additional patent applications ... Office. , The patented inventions address two of the ... and regenerative medicine. Adult stem cells are difficult ...
(Date:7/30/2014)... , July 30, 2014  Decision Resources ... and medical directors in the United ... of biosimilar market penetration will be the level ... (MCOs) and the expected lower cost to patients. ... biosimilars that meet their pricing expectations in order ...
(Date:7/30/2014)... 2014 Selexis SA , a ... discovery and mammalian cell line development, announced today new ... will be presented at the 10th Annual Cell ... 8 – 10, 2014 at the Double Tree by ... following abstract will be presented during an oral presentation: ...
(Date:7/30/2014)... 30, 2014 BCC Research ( http://www.bccresearch.com ... for Enzymes in Industrial Applications , the global market ... $7.1 billion by 2018, registering a five-year compound annual ... to be recorded in the detergent enzyme segment with ... Enzyme technology has influenced almost every sector of industrial ...
Breaking Biology Technology:The Adult Stem Cell Technology Center, LLC Launches A Marketing Campaign To License Adult Stem Cell Biotechnologies 2The Adult Stem Cell Technology Center, LLC Launches A Marketing Campaign To License Adult Stem Cell Biotechnologies 3Surveyed U.S. Payers Expect Cost Savings to MCOs and Patients to be the Strongest Drivers of Biosimilar Uptake 2Surveyed U.S. Payers Expect Cost Savings to MCOs and Patients to be the Strongest Drivers of Biosimilar Uptake 3Selexis SA to Present New Data and a Case Study at IBC’s Cell Line Development and Engineering Conference 2Selexis SA to Present New Data and a Case Study at IBC’s Cell Line Development and Engineering Conference 3Global Market for Industrial Enzymes to Reach Nearly $7.1 Billion by 2018; Detergent Enzyme Market to Record Maximum Growth 2Global Market for Industrial Enzymes to Reach Nearly $7.1 Billion by 2018; Detergent Enzyme Market to Record Maximum Growth 3
... N.J., Sept. 30 Informex ( http://www.informex.com ... of high-value chemistry for a broad range of applications, ... will occur on November 9, 2010 in Milwaukee, Wisconsin. ... Informex initiative to act as a knowledge conduit for ...
... Results From Phase III GETGOAL Clinical Trial Using Once-Daily Lixisenatide in... -- COPENHAGEN, September 30, 2010 ... ... (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... function(data) { var s = ,; var first_result; // Results are keyed by longUrl, so we need ...
... Offer for Movetis NV and Commencement of... -- DUBLIN, September 30, 2010 ... ... --> ... = ,; var first_result; // Results are keyed by longUrl, so we need to grab the first ...
Cached Biology Technology:Inaugural Pharma Exchange Conference Produced by Informex to Draw Together Milwaukee, Wisconsin Chemical Industry 2Inaugural Pharma Exchange Conference Produced by Informex to Draw Together Milwaukee, Wisconsin Chemical Industry 3Positive Top-line Results From Phase III GETGOAL Clinical Trial Using Once-Daily Lixisenatide in Combination With Basal Insulin 2Positive Top-line Results From Phase III GETGOAL Clinical Trial Using Once-Daily Lixisenatide in Combination With Basal Insulin 3Positive Top-line Results From Phase III GETGOAL Clinical Trial Using Once-Daily Lixisenatide in Combination With Basal Insulin 4Positive Top-line Results From Phase III GETGOAL Clinical Trial Using Once-Daily Lixisenatide in Combination With Basal Insulin 5Positive Top-line Results From Phase III GETGOAL Clinical Trial Using Once-Daily Lixisenatide in Combination With Basal Insulin 6Positive Top-line Results From Phase III GETGOAL Clinical Trial Using Once-Daily Lixisenatide in Combination With Basal Insulin 7Positive Top-line Results From Phase III GETGOAL Clinical Trial Using Once-Daily Lixisenatide in Combination With Basal Insulin 8Positive Top-line Results From Phase III GETGOAL Clinical Trial Using Once-Daily Lixisenatide in Combination With Basal Insulin 9Positive Top-line Results From Phase III GETGOAL Clinical Trial Using Once-Daily Lixisenatide in Combination With Basal Insulin 10Shire Announces Results of the Tender Offer for Movetis NV and Commencement of Squeeze-Out Tender Period 2Shire Announces Results of the Tender Offer for Movetis NV and Commencement of Squeeze-Out Tender Period 3Shire Announces Results of the Tender Offer for Movetis NV and Commencement of Squeeze-Out Tender Period 4Shire Announces Results of the Tender Offer for Movetis NV and Commencement of Squeeze-Out Tender Period 5Shire Announces Results of the Tender Offer for Movetis NV and Commencement of Squeeze-Out Tender Period 6Shire Announces Results of the Tender Offer for Movetis NV and Commencement of Squeeze-Out Tender Period 7Shire Announces Results of the Tender Offer for Movetis NV and Commencement of Squeeze-Out Tender Period 8
MOUSE ANTI RAT KAPPA/LAMBDA:HRP Immunogen: MARK-1: Rat kappa light chains (IR202 and IR968)MARL-15: Rat lambda light chains (RH58, IR31)...
Request Info...
SAIVI Alexa Fluor 680 injectable contrast agent *bovine serum albumin*...
RABBIT ANTI QUINOLINIC ACID...
Biology Products: