Navigation Links
Potential heart benefit found in stem cells

a heart attack."

Beneficial Effect of Combined Intramyocardial and Intracoronary Administration of Autologous Stem Cells on Global and Regional Left Ventricular Function and Myocardial Perfusion in Patients with Ischaemic Cardiomyopathy (Abstract 934-173)

Yet another potential new source for stem cells to be used for cardiac therapy is the bone marrow. To improve global left ventricular ejection fraction (EF, the volume of blood pumped out of the heart's main chamber during a single beat) and regional left ventricular wall motion, which is related to ejection fraction, researchers evaluated a treatment with bone marrow-derived cells, attempting to clarify the extent of stress-induced or rest perfusion defect (scar tissue) in patients with ischemic cardiomyopathy, or blockages in the arteries leading to the heart infarction.

In the study, 17 patients with ischemic cardiomyopathy were treated with a combined percutaneous injection (both intramyocardial and intracoronary, either the heart muscle or the heart's artery) of bone marrow-derived mononuclear cells. At baseline and follow-up evaluation, the investigators reviewed the myocardial viability and local wall motion abnormalities, as well as the size of resting and stress-induced perfusion defects. They also measured the global EF and the wall motion score index, which measures the percentage of normal functioning muscle tissue in the heart wall.

The combined stem cell injection resulted in an increase in global EF, (from 34.8 to 39.5 percent), as well as a significant increase in wall motion at the six-month follow up. The team noted a trend to smaller stress-induced defects, and found that the number of bone-marrow stem cells injected was positively related to the follow-up EF levels, and negatively correlated to the stress-induced and resting perfusion defects.

"In at-risk patients, combined treatment with bone-marrow derived stem cells may offer an effective a
'"/>

Source:American College of Cardiology


Page: 1 2 3 4 5

Related biology news :

1. Novel Enzyme Shows Potential As An Anti-HIV Target
2. Potential Cure for Lymphoma in HIV patients
3. Potential treatments for neurofibromatosis
4. Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks
5. Potential Drug Target For Treating Cocaine Abuse Found
6. Potential vaccine developed for deadly leishmaniasis disease
7. UCSD team discovers specialized, rare heart stem cells in newborns
8. Single stem cells from bone heal a broken heart
9. Python a hearty eater
10. Columbia study shows widely used artery clearing device does not help patients during heart attack
11. Researchers reveal secret of key protein in brain and heart function
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Potential heart benefit found stem cells

(Date:12/24/2014)... , Dec. 23, 2014  Since its launch in December 2014, the ... eliminate the pain of trying to remember their usernames and ... fused to their smartphones. To assist people who have struggled ... company that created 1U and focuses on redefining identity, announced ...
(Date:12/19/2014)... , Dec. 18, 2014 Research and Markets ... "Micro Market Monitor: North America Perimeter Security Systems Market" ... The North American perimeter security market is ... to 2019. Although the U.S. market holds a larger share ...
(Date:12/17/2014)... NEW YORK , Dec. 15, 2014  HITLAB SM ... Practices (GCP) audit to confirm its adherence to current ... enables HITLAB to conduct regulated smart device and smart ... safety and research quality. "HITLAB is determined ...
Breaking Biology News(10 mins):1U Offers Best Solution to the Username / Password Dilemma: For FREE! 21U Offers Best Solution to the Username / Password Dilemma: For FREE! 3Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3HITLAB Completes GCP Audit for FDA Smart Device & App Compliance 2
... may help to protect against some food allergies. Kefir, a ... health food, and is often used to wean babies, as ... in children under the age of three, with around 5-8% ... of the problematic food. , "Friendly" bacteria in kefir may ...
... in the event of a large-scale smallpox bioterrorist attack ... by researchers at Fred Hutchinson Cancer Research Center that ... , Instead, the current U.S. government policy of post-release ... workers and close contacts would be sufficient to thwart ...
... information is passed from parents to offspring via sperm or ... as yeast, the genes can be passed to the next ... occur in the genetic material after it has been duplicated ... mature gametes or spores. Near the end of the process, ...
Cached Biology News:Friendly bacteria in alcoholic milkshake could fight food allergies 2Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 2Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 3Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 4Mass vaccination unnecessary in the event of a large bioterrorist US smallpox attack 5Single molecular 'mark' seen as pivotal for genome compaction in spores and sperm 2
(Date:1/23/2015)... Jan. 23, 2015  Array BioPharma Inc. (NASDAQ: ... definitive agreement with Novartis Pharma AG to acquire worldwide ... Phase 3 development.  This agreement is conditional on the closing ... on April 22, 2014, which are expected to close in ...
(Date:1/22/2015)... January 22, 2015 Shimadzu Scientific ... UV-1280 multipurpose UV-visible spectrophotometer. Offering wavelength scanning from ... is ideal for applications in a variety of ... , The user-friendly UV-1280 enables intuitive operation, while ...
(Date:1/22/2015)... , Jan. 22, 2015  Transwestern | RBJ today announces ... of office space for Shire a leading biopharmaceutical company, at ... Transwestern | RBJ,s Robert Richards , president, and ... lease for the entire five-floor building at 95 Hayden Ave. ...
(Date:1/22/2015)... January 22, 2015 Protocol Networks brings ... growing team of brand-neutral, independent consultants, Protocol Networks has ... explained that over the years, his company has attracted ... Town of Plainfield, as well as others. With the ...
Breaking Biology Technology:Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 2Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 3Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 4Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 5Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 6Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 7Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2
... WASHINGTON - A delegation led by Governor Doyle and ... week for the biotechnology industrys leading conference with goals ... states research and university community and to let others ... to members of the group, the delegation met its ...
... get difficult, its the companies who dont panic, that will ... years ago, I was working on a project for the ... San Jose, California. I was arranging and conducting seminars for ... again going through a make or break situation with many ...
... WI - GE Medical Systems, a unit of General ... by the U.S. Food and Drug Administration to begin ... (MRI) system. The Signa EXCITE 3.0T combines the increased ... with the breadth of imaging capabilities found on premium ...
Cached Biology Technology:On site at BIO 2003 2On site at BIO 2003 3On site at BIO 2003 4On site at BIO 2003 5A Race without a Finish Line! 2GE Medical Systems Receives FDA Clearance for New MRI System 2
Recombinant DNA polymerase from Thermus aquaticus expressed in E. coli; 5 units/L; 1 tube of 1, 000 units enzyme/tube w/Buffer II and MgCl2...
Recombinant DNA polymerase from Thermus aquaticus expressed in E. coli; 5 units/uL; 25 tubes of 1, 000 units enzyme/tube w/ Buffer I...
A robust formulation of Taq Polymerase supplied with a 10X colored reaction buffer which allows Direct Gel-Loading...
Ps-Aeruginosa (IgA) -Ab EIA Sample Size: 100 l...
Biology Products: