Navigation Links
Potential heart benefit found in stem cells

a heart attack."

Beneficial Effect of Combined Intramyocardial and Intracoronary Administration of Autologous Stem Cells on Global and Regional Left Ventricular Function and Myocardial Perfusion in Patients with Ischaemic Cardiomyopathy (Abstract 934-173)

Yet another potential new source for stem cells to be used for cardiac therapy is the bone marrow. To improve global left ventricular ejection fraction (EF, the volume of blood pumped out of the heart's main chamber during a single beat) and regional left ventricular wall motion, which is related to ejection fraction, researchers evaluated a treatment with bone marrow-derived cells, attempting to clarify the extent of stress-induced or rest perfusion defect (scar tissue) in patients with ischemic cardiomyopathy, or blockages in the arteries leading to the heart infarction.

In the study, 17 patients with ischemic cardiomyopathy were treated with a combined percutaneous injection (both intramyocardial and intracoronary, either the heart muscle or the heart's artery) of bone marrow-derived mononuclear cells. At baseline and follow-up evaluation, the investigators reviewed the myocardial viability and local wall motion abnormalities, as well as the size of resting and stress-induced perfusion defects. They also measured the global EF and the wall motion score index, which measures the percentage of normal functioning muscle tissue in the heart wall.

The combined stem cell injection resulted in an increase in global EF, (from 34.8 to 39.5 percent), as well as a significant increase in wall motion at the six-month follow up. The team noted a trend to smaller stress-induced defects, and found that the number of bone-marrow stem cells injected was positively related to the follow-up EF levels, and negatively correlated to the stress-induced and resting perfusion defects.

"In at-risk patients, combined treatment with bone-marrow derived stem cells may offer an effective a
'"/>

Source:American College of Cardiology


Page: 1 2 3 4 5

Related biology news :

1. Novel Enzyme Shows Potential As An Anti-HIV Target
2. Potential Cure for Lymphoma in HIV patients
3. Potential treatments for neurofibromatosis
4. Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks
5. Potential Drug Target For Treating Cocaine Abuse Found
6. Potential vaccine developed for deadly leishmaniasis disease
7. UCSD team discovers specialized, rare heart stem cells in newborns
8. Single stem cells from bone heal a broken heart
9. Python a hearty eater
10. Columbia study shows widely used artery clearing device does not help patients during heart attack
11. Researchers reveal secret of key protein in brain and heart function
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Potential heart benefit found stem cells

(Date:8/27/2014)... that a single fungal cell or bacterial colony exerts on ... a heavy role in setting up some of the most ... be too much of a stretch to say that plants ... respond to the touch of beneficial fungi, according to a ... at the University of Wisconsin-Madison. , "Many people have ...
(Date:8/27/2014)... mysteries of the human genome was unveiled today in ... detailed comparison yet of how the genomes of the ... research, appearing August 28 in in the journal ... three species, genomes is "read out," and how their ... results add billions of entries to a publicly available ...
(Date:8/27/2014)... have identified a gene that could help scientists engineer ... in the cell membrane of plants that senses changes ... machinery accordingly. , "It,s similar to a thermostat," ... Duke. , The findings, which appear Aug. 28 ... easier to feed the world,s growing population in the ...
Breaking Biology News(10 mins):A touching story: The ancient conversation between plants, fungi and bacteria 2A touching story: The ancient conversation between plants, fungi and bacteria 3Encyclopedia of how genomes function gets much bigger 2Encyclopedia of how genomes function gets much bigger 3Encyclopedia of how genomes function gets much bigger 4Water 'thermostat' could help engineer drought-resistant crops 2
... 27, 2013) A team of Korean ... the neurobehavioral function of six week-old mice ... to treat hypoxic-ischemic brain injury, and found that ... through exercise-induced fibroblast growth factor 2 (FGF2), a ...
... Researchers from Lund University, Yale University and the University of ... cuckolded males in many species still provide paternal care. When ... successful. In many species males put a lot of ... At first glance this makes no sense at all because ...
... Since its introduction fifty or so years ago, thermography has ... lameness in horses. The method is fast and safe ... body surface emits infrared radiation that can be detected by ... use. The camera produces a coloured image that shows ...
Cached Biology News:Environmental enrichment important factor impacting cell transplantation and brain repair 2Environmental enrichment important factor impacting cell transplantation and brain repair 3Why sticking around is sometimes the better choice 2Blowing in the wind: How accurate is thermography of horses' legs? 2
(Date:8/27/2014)... (PRWEB) August 27, 2014 In ... through Lawrence Livermore National Security LLC ... develop and deliver a state-of-the-art laser system for ... (ELI Beamlines), under construction in the Czech Republic. ... the laser system, called the " High repetition-rate ...
(Date:8/27/2014)... 27, 2014 The Global and China ... on the current state of the Trifluoroacetic Acid industry ... basic overview of the industry, including definitions, applications and ... market analysis are provided with a focus on history, ... comparison between the international and Chinese situation is also ...
(Date:8/27/2014)... Aug. 27, 2014  A novel biomarker for ... physicians better identify early-stage disease, when treatment can ... to a new study in The Journal of ... DGX ) and other institutions found ... outperformed conventional antibody-serum testing, including rheumatoid factor (RF) ...
(Date:8/27/2014)... 27, 2014 Flagship Biosciences LLC, a ... to the pharmaceutical and medical device industries, has announced ... fast growing company has consolidated its histology and tissue ... to Westminster, CO, just north of Denver. The ... W. 103rd Ave., Suite 100, Westminster, CO 80021 , ...
Breaking Biology Technology:LLNL Synchs up with ELI Beamlines on Timing System 2LLNL Synchs up with ELI Beamlines on Timing System 3Trifluoroacetic Acid Industry (Asia, Europe, North America, ROW) Analysis Report Now Available at ReportsnReports.com 2Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 2Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 3Novel Biomarker Detects Early Rheumatoid Arthritis Better than Conventional Methods Alone, According to Journal of Rheumatology Study 4Flagship Biosciences Announces Relocation and Expansion 2
... SAN DIEGO, Jan. 26 Amylin Pharmaceuticals, Inc.,(Nasdaq: ... P. Mihalik has been appointed,Senior Vice President, Sales ... more than 30 years of experience across multiple ... management,product launches and brand management. His career has ...
... and BINGHAM FARMS, Mich., Jan. 26 WellCentive, ... by my1HIE(sm) (My,One Health Information Exchange) as its ... Through the use of WellCentive Registry, ... providers in Southeast Michigan will be better able ...
... Sirion Therapeutics, Inc., a privately held ophthalmic-focused biopharmaceutical ... for ganciclovir ophthalmic gel, 0.15%, has been accepted for ... Sirion Therapeutics is seeking approval for ganciclovir as a ... the herpes simplex virus. The FDA has issued an ...
Cached Biology Technology:Amylin Pharmaceuticals Appoints Vincent Mihalik Senior Vice President, Sales and Marketing and Chief Commercial Officer 2Amylin Pharmaceuticals Appoints Vincent Mihalik Senior Vice President, Sales and Marketing and Chief Commercial Officer 3my1HIE(sm) Implements WellCentive Registry 2my1HIE(sm) Implements WellCentive Registry 3Sirion Therapeutics New Drug Application for Ganciclovir is Accepted for Review by the FDA for the Treatment of Ocular Herpes 2Sirion Therapeutics New Drug Application for Ganciclovir is Accepted for Review by the FDA for the Treatment of Ocular Herpes 3
S-100A10 (H-80)...
Vapor phase risers are available in various heights to accomodate a variety of inventory solutions. Risers are used to creat a false bottom in which the tanks platform rests and Liquid nitrogen is s...
... single-stranded DNA and RNA endonucleolytically to ... (DNA:DNA, DNA:RNA or RNA:RNA) are resistant ... concentrations of enzyme (1). The enzyme ... from double-stranded DNA (2), for selective ...
SP6 RNA Polymerase, 50 l, 20 U/l ,Cap Scribe Buffer, 100 l, 5x conc....
Biology Products: