Navigation Links
Polymer aids in blood clotting, pointing way to new treatment

treatments for situations involving uncontrollable bleeding.

Such scenarios, Morrissey said, could include treatment for wounds sustained on battlefields or in accidents, or for hemophilia and other diseases with coagulation deficits.

"The big picture is that we've found a new function for an ancient molecule," he said. "Polyphosphate has been around for billions of years. Roberto's discovery that the granules in platelets are like the granules in trypanosomatids was a key breakthrough."

Docampo's recognition of the acidocalcisome in various organisms has enabled scientists to detect muscle-like motors that operate a variety of movements within cells, said Arthur Kornberg, who won the 1959 Nobel Prize in Medicine or Physiology for discovering mechanisms in the synthesis of ribonucleic acid and deoxyribonucleic acid.

"Roberto has discovered a novel structure of major metabolic importance that regulates the levels of calcium and phosphate within all cells," said Kornberg, an emeritus professor of biochemistry in Stanford University's School of Medicine. "This acidocalcisome has been identified in cells as diverse as bacteria, the protozoa of tropical diseases and the blood-clotting elements of human blood."

Although no longer at Illinois, Docampo said he's thrilled that the research will be continuing through the Carver grant to the U. of I. "It's theoretically possible to use this discovery to find ways to help the body's own blood-clotting mechanisms," he said. "It could be potentially very useful to save lives. Many people with severe injuries die from blood loss not directly resulting from their injuries. This research could open doors to helping in that regard."

In his new lab at Georgia, Docampo will continue to study the purification of polyphosphate present in platelets and on the enzymes involved in its metabolism.

Co-authors with Morrissey and Docampo on the PNAS paper were Peter Rohloff, an Illinois M
'"/>

Source:University of Illinois at Urbana-Champaign


Page: 1 2 3 4

Related biology news :

1. Polymers with copper show promise for implanted sensors
2. Polymer gel can block toxic leakage problem in gene therapy
3. Polymers show promise for lab-on-a-chip technology
4. White blood cell waste disposal system plays critical regulatory role
5. Epstein-Barr virus protein crucial to its role in blood cancers
6. New insight into regulation of blood stem cells
7. Nano-bumps could help repair clogged blood vessels
8. First technology to remove prions that cause vCJD from blood launched
9. Breakthrough isolating embryo-quality stem cells from blood
10. Thai spice helps cut blood sugar swings
11. Study shows humans have ability to track odors, much like bloodhounds
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Polymer aids blood clotting pointing way new treatment

(Date:8/21/2014)... A study recently published in the journal Carcinogenesis ... a new role for the protein adenomatous polyposis coli ... of cancer-related deaths in the U.S. , Lead author ... Biosciences and co-leader of the Cancer Biology program at ... of her career trying to understand the various activities ...
(Date:8/21/2014)... An Australian National University (ANU) team has successfully replicated ... way for biological systems powered by sunlight which could ... and so is sunlight. It is an exciting prospect ... cheaply and safely," said Dr Kastoori Hingorani, from the ... ANU Research School of Biology. , Hydrogen offers potential ...
(Date:8/20/2014)... 20, 2014 George E. Fox, a John and Rebecca ... Houston (UH), was named a fellow in the International Society ... , Fox is one of four members two from ... chosen as fellows in 2014. Fellows are elected every three ... than 500 members from more than 20 countries, the ISSOL ...
Breaking Biology News(10 mins):Research offers insight into cellular biology of colorectal cancer 2Research offers insight into cellular biology of colorectal cancer 3Water and sunlight the formula for sustainable fuel 2UH professor named fellow by International Astrobiology Society 2
... was identified by ancient Egyptians. Genetic analysis done by ... the animal,s range and including DNA from mummified crocodile remains ... name., "This paper provides a remarkable surprise: the Nile crocodile ... demonstrates two species - living side-by side - constitute what ...
... Bone marrow-derived stem cells (BMDCs) have been recognized as ... cell populations in a variety of organs under both normal ... repairing damaged brain tissue or helping to restore lost neural ... cerebellum at the back of the brain. In a recent ...
... Webb from the School of Chemical Engineering and Analytical ... and Excellence Award for Bioprocessing. They received the ... co-production of fuels and chemicals: The biochemical production of ... place last month at the ICC in Birmingham. ...
Cached Biology News:Bone marrow-derived cells differentiate in the brain through mechanisms of plasticity 2Award success for University 2
(Date:8/20/2014)... 20, 2014 Clintrax Global, Inc., a ... Raleigh, NC , recently announced ... Vice President of Administration. As ... corporate processes, including their alignment with company objectives ... worked as an HR executive, specializing in needs ...
(Date:8/20/2014)... High performance computing (HPC) will be ... climate and Earth system model to address the ... Eight national laboratories, including Lawrence Livermore , ... Atmospheric Research, four academic institutions and one private-sector ... laboratories include Argonne, Brookhaven, Lawrence Berkeley, Los Alamos, ...
(Date:8/20/2014)... Aug. 20, 2014 /PRNewswire-iReach/ -- A case study ... between the school,s bioengineering department and the Intel® ... Intel® Software Academic Program, UCSD,s research focuses on ... human body.  Photo - ... the work of Dr. Todd P. Coleman ...
(Date:8/19/2014)... Columbia, Md. (PRWEB) August 19, 2014 ... integrated liquid chromatography systems, Prominence-i and Nexera-i, adding ... UHPLC systems. Combining excellent functionality, an intuitive operating ... performance and a more efficient workflow for conventional ... systems feature innovative, intuitive and intelligent design so ...
Breaking Biology Technology:Clintrax Global, Inc. Announces Addition to Executive Team 2New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 3Intel and University of San Diego Bioengineering Department Release Case Study on Health Sciences Research 2Shimadzu’s New i-Series Integrated Liquid Chromatography Systems Provide Laboratories Wider Range of Analytical Capabilities 2Shimadzu’s New i-Series Integrated Liquid Chromatography Systems Provide Laboratories Wider Range of Analytical Capabilities 3
... , , Multiporator , , , , , , ... Protocol No. 4308 915.029 11/1999 , , , ... , Cell line , ... Transfection with , Plasmid pEGFP-N1 (in bidistilled H 2 O), , ...
... , , , , , , , Multiporator / Electroporator 2510 , ... , Transformation Protocol , Protocol ... , , , , , ... , , Cell type , ...
... , , , , Multiporator / Electroporator 2510 , , , , ... Transformation Protocol , Protocol No. 4308 915.528 01/2002 , ... , , , ... , Cell type , Bacteria, gram negative, ...
Cached Biology Technology:293 T 2Staphylococcus aureus 2Pseudomonas aeruginosa 2
Bethyl Laboratories packages antibodies, conjugates and calibrators to provide quantitative ELISA kits. Each kit contains the following components, sufficient for 1000 single well assays....
QML offers standard and customized paraffin embedded tissue blocks....
... include: ,ISH Protocol Development ,Probe ... ,RNA and DNA Screenings in ... Tissues ,Double Labeling of RNA ... Tissues ,RNA and DNA Localization ...
... involves the optimization of immunostaining. ... of the primary antibody, selection ... (e.g. Alk. Phos., HRP, fluorescence, ... detection, evaluation by light or ...
Biology Products: