Navigation Links
Physical and functional interaction of key cell growth molecules linked to cancer

ies, there has previously been no direct connection made between EGFR and the iNOS/NO pathway.

The researchers conclude that the complex formed by EGFR and STAT3 can directly regulate gene expression and provides a new transcriptional mechanism that may play a significant role in human cancers, transducing cell signals from outside the cell into the nucleus. According to Dr. Hung, "As in OS serves as a direct target of the identified EGFR/STAT3 transcriptional complex, the deregulated iNOS/NO pathway may, in part, contribute to the malignant biology of tumor cells with high levels of nuclear EGFR and STAT3." This research may open new avenues for designing anticancer therapies against EGFR, STAT3, and iNOS/NO.


'"/>

Source:Cell Press


Page: 1 2

Related biology news :

1. Towards precise classification of cancers based on robust gene functional expression profiles
2. Bone marrow cells can become functional gut lining cells
3. Virus-host interactions at sea effect global photosynthesis
4. Future diabetes drugs may target new protein interaction
5. Computational verification of protein-protein interactions by orthologous co-expression
6. Confirmation of human protein interaction data by human expression data
7. Complex gene interactions account for autism risk
8. Image of myosin-actin interaction revealed in cover story of Molecular Cell
9. A real time look at interactions between RNA and proteins
10. U of MN researchers develop way to visualize synchronized interactions of nerve cells in the brain
11. Biologists visualize protein interaction that may initiate viral infection
Post Your Comments:
(Date:7/24/2014)... over a 35 year period in which the human ... humans on declining animal numbers. This decline matters because ... crustaceans, slugs and worms bring to our day-to-day lives, ... nutrient cycling, water filtration and human health. , The ... UCL, Stanford and UCSB, focused on the demise of ...
(Date:7/24/2014)... on different species of fish, according to a ... Exeter which tested fish anti-predator behaviour. , ... predator model when exposed to additional noise, whereas ... , Lead author Dr Irene Voellmy of Bristol,s ... many aquatic environments have increased substantially during the ...
(Date:7/24/2014)... study has identified two factors that characterize sustainable ... production of highly qualified physics teachers. Specifically, one ... physics teacher education in combination with institutional motivation ... viable. Science, Technology, Engineering and Math (STEM) teacher ... study points the way for institutions seeking to ...
Breaking Biology News(10 mins):Invertebrate numbers nearly halve as human population doubles 2Invertebrate numbers nearly halve as human population doubles 3Creating sustainable STEM teacher preparation programs 2
... a widespread assumption, global warming is unlikely to expand the ... factors that are at work to corral the disease. ... of Florida researchers in a paper set to appear May ... public policy makers have been concerned that warming temperatures would ...
... satellite swept over the Gulf of Mexico oil spill from ... Spectroradiometer instrument captured sunglints in a visible image of the ... sunglint within the area of the gray-beige colored spill. Sunglint ... surface. In calm waters, the rounded image of the sun ...
... release is available in Spanish . , ... bioGUNE, in collaboration with the Universidad de Kentucky (USA), have ... types of prions (the pathogen agents responsible for transmissible spongiform ... gives the opportunity to control prion disease in deer, which ...
Cached Biology News:Scientists: Malaria control to overcome disease’s spread as climate warms 2Researchers embark on work to control the prion epidemic affecting deer in the USA 2Researchers embark on work to control the prion epidemic affecting deer in the USA 3
(Date:7/24/2014)... 2014  ECC West Africa, LLC (ECC) signed a ... University College Hospital (UCH) Ibadan Board of Management for ... design, construct, and operate and maintain a new, state-of-the-art ... Under the first of the 4-phase project, ECC will ... applications. UCH Ibadan intends to finance and develop the ...
(Date:7/24/2014)... rely on sophisticated equipment, trained personnel, and detection ... against terrorist attacks. A revolutionary new electronic chip ... their job much easier. , The groundbreaking nanotechnology-inspired ... Aviv University ,s School of Chemistry and Center ... Herzliya company Tracense, picks up the scent of ...
(Date:7/24/2014)... A research team led by group leader Yung-Eun ... technology to synthesize sulfur-doped and nitrogen-doped graphenes which ... secondary batteries and fuel cells. Yung-Eun Sung is ... Nanoparticle Research at Institute for Basic Science* (IBS) ... , This achievement has great significance with regards ...
(Date:7/24/2014)... Quantum computers have yet to materialise. Yet, scientists ... making such computers faster. One such approach relies ... controlled by applying an electric field. A new ... coherently coupled quantum dots (TQDs) with electrical impulses ... for example, should TQDs be used as quantum ...
Breaking Biology Technology:ECC Signs a Contract for the Finance, Design, and Construction of a Premier Cancer Institute in Ibadan, Nigeria 2Nano-sized chip 'sniffs out' explosives far better than trained dogs 2
... development and use of devices that are one-billionth of ... as a science, and the term now describes many ... than 1,000 nanometers of the substances involved in the ... the creation of exciting and innovative new products and ...
... an electronic newsletter is like giving out your phone number ... what you want. Sometimes you never hear from them again. ... are the blind date from hell. You are deluged by ... highlighting how wonderful, fast, reliable, and inexpensive their products are. ...
... with these three words, after all that has happened this ... the importance of being current with ones network security and ... came via the blaster worm, which took advantage of those ... Following closely on its heels were Sobig, Nacha, and Welchia. ...
Cached Biology Technology:Nanotechnology - Natures Lego Blocks! 2Quantity versus Quality: Effective E-Marketing Relationships 2Quantity versus Quality: Effective E-Marketing Relationships 3
... potent TURBO DNase (patent pending) in the TURBO ... DNA removal capabilities. TURBO DNase is a recombinant, ... more efficient than wild type DNase I in ... DNase binds DNA substrates 6-fold more tightly than ...
...
Lyophilized. Purity: ≥90% by electrophoresis. Reconstitute in 0.3% NaCl. Prepared from serum that has been shown by certified tests to be negative for HBsAg and for HIV and HCV antibodies. ...
Porcine Pulmonary Artery Endothelial Cells (PPAEC) (>500,000 cells)...
Biology Products: