Navigation Links
Physical and functional interaction of key cell growth molecules linked to cancer

ies, there has previously been no direct connection made between EGFR and the iNOS/NO pathway.

The researchers conclude that the complex formed by EGFR and STAT3 can directly regulate gene expression and provides a new transcriptional mechanism that may play a significant role in human cancers, transducing cell signals from outside the cell into the nucleus. According to Dr. Hung, "As in OS serves as a direct target of the identified EGFR/STAT3 transcriptional complex, the deregulated iNOS/NO pathway may, in part, contribute to the malignant biology of tumor cells with high levels of nuclear EGFR and STAT3." This research may open new avenues for designing anticancer therapies against EGFR, STAT3, and iNOS/NO.


'"/>

Source:Cell Press


Page: 1 2

Related biology news :

1. Towards precise classification of cancers based on robust gene functional expression profiles
2. Bone marrow cells can become functional gut lining cells
3. Virus-host interactions at sea effect global photosynthesis
4. Future diabetes drugs may target new protein interaction
5. Computational verification of protein-protein interactions by orthologous co-expression
6. Confirmation of human protein interaction data by human expression data
7. Complex gene interactions account for autism risk
8. Image of myosin-actin interaction revealed in cover story of Molecular Cell
9. A real time look at interactions between RNA and proteins
10. U of MN researchers develop way to visualize synchronized interactions of nerve cells in the brain
11. Biologists visualize protein interaction that may initiate viral infection

Post Your Comments:
(Date:11/24/2009)...ambridge, Md. (November 24, 2009) New research on... river ecosystems reveals predictable temporal pat...communities as markers for monitoring climate chan... week in the Proceedings of the National Academy ...ommunities in the six rivers shifted synchronously...
(Date:11/23/2009)... TORONTO, November 23, 2009 - The time of day matt...g to a new paper produced by a research team led b...o Scarborough,s vice-principal for research and co...logy at the St. George campus. , Capitalizing ... poplar tree, the research team examined how popla...
(Date:11/23/2009)... AMES, Iowa - The only swine vaccine available for... herd infected with the virus. The vaccination mar... herd diagnosed with the pandemic flu., Iowa Sta...cience, developed the vaccine this summer and has ...in Iowa, Kansas and Illinois for several weeks., ...
Breaking Biology News(10 mins):Researchers establish common seasonal pattern among bacterial communities in Arctic rivers 2Time of day matters to thirsty trees, U of T researcher discovers 2Iowa State researcher produces, ships only H1N1 vaccine available for swine 2Frost 26 Sullivan European Gastroenterology Technology Implementation of the Year Award Bestowed on Crospon 50479 1Frost 26 Sullivan European Gastroenterology Technology Implementation of the Year Award Bestowed on Crospon 50479 2Frost 26 Sullivan European Gastroenterology Technology Implementation of the Year Award Bestowed on Crospon 50479 3A young brain for an old bee 9076 1A young brain for an old bee 9076 2Medco Announces Date for Second Quarter 2009 Financial Results 50475 1Medco Announces Date for Second Quarter 2009 Financial Results 50475 2
...o choose the wood they eat may provide opportuniti...s and also may provide insights into the "cocktail... most noise but have some signals that trigger att...igence. , CSIRO entomologist Theo Evans says labo...eir ability to detect vibrations to determine whic...
...,Medicine are conducting a clinical trial using st...new blood vessels that could improve,circulation i... legs --,a condition called peripheral vascular d... blood flow to the muscles of,the legs, especially...ing or fatigue in the muscles of their legs when t...
...omatically grouped fluorescently tagged proteins f...l feat opens a new way to,identify disease protein...ns cluster together inside a cell.,The approach, d...s,existing visual methods to localize proteins ins...report, "Data Mining in Genomics and,Proteomics," ...
Other Biology News:Termites feed through good vibrations 2Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs 2New, automated tool successfully classifies and relates proteins in unprecedented way 2
(Date:11/24/2009)...-Asia/--NODPharmaceuticalsInc.announced,theUSPaten...cationfor,itsnano-particleoraldeliveryorNODtechnol...htoincorporatepeptidesor,proteinsintobio-adhesiven...administeredasinjections.NODtechnologyisaplatformt...ssuchasinsulin,interferon,growthhormone,exenatide...
(Date:11/24/2009)...--BlueMarbleEnergyCorp.announcedtodaythatthecompan...ecentlyawarded$2millionbyWashingtonState,sCommunit...cpartnershiptoconstructthestate,sfirstspecialtybio...investmentwillsignificantlyspeedthedevelopmentofou...,"saidBlueMarbleEnergyCEOKellyOgilvie."Wearegratef...
(Date:11/24/2009)...NTO,Nov.24/PRNewswire-FirstCall/-HamiltonThorneLtd...oviderofadvancedlasersystemsandinstrumentsforthest...tedoperationalandfinancialresultsforthethirdquarte...enuewas$1.46millioncomparedwith$1.43millioninQ3200...percentinQ3,2008,-Netlossreducedto$148,000compared...
(Date:11/24/2009)...PRNewswire-FirstCall/--GenomicHealth,Inc.(Nasdaq: ...ExecutiveChairman,willpresentatthe21stAnnualPiperJ...ecember1,2009at10:00a.m.ET. ,, Toaccessthelivea...ittheInvestorRelationssectionofGenomicHealth,swebs...necttothewebsiteatleast15minutespriortothebeginnin...
Breaking Biology Technology:Blue Marble Energy, OPDA Awarded $2M by WA's Community Economic Revitalization Board 2Hamilton Thorne announces third quarter results 2Hamilton Thorne announces third quarter results 3Hamilton Thorne announces third quarter results 4Hamilton Thorne announces third quarter results 5Hamilton Thorne announces third quarter results 6Hamilton Thorne announces third quarter results 7Genomic Health to Present at Piper Jaffray Health Care Conference 2
...e Symbol: RVX, CALGARY, Oct. 7 /PRNewswire-FirstC...mpany") (TSX:RVX) announced today that in light of... shares management feels,it is prudent to restate ...ot stronger in regards to the Company,s science an...e price drop other than the current global,conditi...
...s., Oct. 7 BioEnergy International, LLC,(BioEnerg...cturer of,next-generation, renewable biochemicals ...Augustine to its Board of Advisors effective Decem...hed leadership and innovation,at the highest level...e as,Chairman and Chief Executive Officer of Lockh...
...DALE, Fla., Oct. 7 Imaging,Diagnostic Systems, In...optical breast cancer imaging systems, announced t...e an order for the first CT Laser Mammography,Syst...://www.newscom.com/cgi-bin/prnh/20040412/IMDSLOGO ...rom the Israel Ministry of,Health which permitted ...
Other Biology Technology:BioEnergy International, LLC Announces Norman R. Augustine to Join Advisory Board 2BioEnergy International, LLC Announces Norman R. Augustine to Join Advisory Board 3Imaging Diagnostic Systems Receives its First Order for its CT Laser Mammography System for Israel 2
Anti-Human DPPII / QPP / DPP7 Affinity Purified Polyclonal Antibody, Biotin Conjugated from R&D Systems
Goat Anti-Human SorCS1 Polyclonal Antibody, Unconjugated from R&D Systems
Anti-Human Apolipoprotein B100 Affinity Purified Polyclonal Antibody, Unconjugated from R&D Systems
Rabbit Anti-Human HCARG Polyclonal Antibody, Unconjugated from Proteintech Group, Inc.
Biology Products: