Navigation Links
Penn researchers study the use of ultrasound for treatment of cancer

For the first time, ultrasound is being used in animal models ?to treat cancer by disrupting tumor blood vessels. Researchers at the University of Pennsylvania School of Medicine completed a study in mice in which they used ultrasound both to see a tumor's blood perfusion and then to treat it with a continuous wave of low-level ultrasound. After three minutes of treatment at an intensity similar to what is used in physiotherapy ultrasound (about 2.5 watts), researchers observed that the tumors had little or no blood supply.

"We used an ultrasound intensity higher than that used for imaging, but much lower than the high intensities used to ablate tissue. And we saw that this new use had a profound effect on shutting down the blood flow to the tumor and reducing the growth of the tumor in mice," said Chandra Sehgal, PhD, Director of Ultrasound Research in the Department of Radiology at Penn and the study's principal investigator.

"We wanted to study this use of ultrasound because we observed that some of these newly formed vessels created by tumors are very weak in nature, and if you turn on low-intensity ultrasound vibrations you can disrupt the blood flow through these vessels," explained Andrew Wood, DVSc, PhD, a co-investigator of the study and based in the University of Pennsylvania School of Veterinary Medicine.

Sehgal adds, "This approach is in keeping with the latest study of cancer treatment utilizing antiangiogenic and antivascular therapies, in which we look for ways to stop the growth of the vessels supplying blood and nutrition to the tumors, rather than develop methods to kill the tumor cells themselves."

For years, ultrasound has been used for clinical imaging and for therapeutic action in physical therapy. But now, Sehgal explains, "These results are extremely encouraging. They raise the possibility that, in the future, treatments with ultrasound either alone or with chemotherapeutic and antivascular agents could be used to treat cancers."


'"/>

Source:University of Pennsylvania School of Medicine


Related biology news :

1. NYU researchers simulate molecular biological clock
2. Vital step in cellular migration described by UCSD medical researchers
3. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
4. UCSD researchers maintain stem cells without contaminated animal feeder layers
5. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
6. New protein discovered by Hebrew University researchers
7. First real-time view of developing neurons reveals surprises, say Stanford researchers
8. Agilent Technologies releases automated literature search tool for biology researchers
9. Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
10. Yale researchers identify molecule for detecting parasitic infection in humans
11. US life expectancy about to decline, researchers say
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/8/2016)... , February 8, 2016 ... platform which presents innovation for clients, comfort and ... called VoiceKey. --> Worldcore is ... innovation for clients, comfort and unbeatable security, with ... --> Worldcore is the first ...
(Date:2/4/2016)... 4, 2016 The field of Human ... the most popular hubs of the biotechnology industry. ... huge studies of human microbiota, have garnered a ... the microbiome space has literally exploded in terms ... This report focuses on biomedical aspects of research, ...
(Date:2/3/2016)... PUNE, India , February 3, 2016 ... to the new market research report "Automated Fingerprint Identification ... (Tenprint Search, Latent Search), Application (Banking & Finance, Government, ... 2020", published by MarketsandMarkets, the market is expected to ... estimated CAGR of 21.0% between 2015 and 2020. The ...
Breaking Biology News(10 mins):
(Date:2/12/2016)... 2016 MedGenome,s Commitment Will ... Understanding of Complex Diseases Such as Cancer, Metabolic ... --> --> MedGenome, the ... a leading provider of genomics research services globally, ... the GenomeAsia 100K consortium as a founding member. ...
(Date:2/11/2016)...  Vermillion, Inc. (NASDAQ: VRML ), a bio-analytical ... formation of the Steering Committee for its Pelvic Mass ... Pelvic masses can present physicians and healthcare professionals ... is ruled out, pelvic masses may include cancers of ... ovarian tumors and gastrointestinal and urinary tract masses. ...
(Date:2/11/2016)... 2016  Spectra BioPharma Selling Solutions (Spectra) is ... biopharma companies the experience, expertise, operational delivery and ... sales teams. Created in concert with industry leading ... strategic and tactical needs of its clients by ... both personal and non-personal promotion. ...
(Date:2/11/2016)... 11, 2016  Dovetail Genomics™ LLC today announced that ... for a planned metagenomic genome assembly service. Richard ... genome assembly method in a talk on Friday, February ... Technology conference in Orlando, Fla. ... datasets is difficult. Using its proprietary Chicago ...
Breaking Biology Technology: