Navigation Links
Peering into the shadow world of RNA

converts specific occurrences of a basic RNA building-block molecule called adenosine into another called inosine. In her laboratory, this simple substitution has been seen to have significant biological effects, altering the expression of certain neurotransmitter genes, for example.

Last year, this work converged with that of researchers investigating an extensive family of small molecules called microRNAs, or miRNAs, non-coding forms of RNA that appear to target and inactivate particular sets of messenger RNAs, thus preventing them from producing protein and effectively silencing the group of genes from which they were transcribed. In that study, Nishikura found that that precursor miRNAs, like messenger RNAs, are themselves subject to specific RNA editing, the result of which is to suppress ?or perhaps refocus ?miRNA expression and activity (http://www.nature.com/nsmb/journal/v13/n1/full/nsmb1041.html).

“MicroRNAs often target a specific set of genes,?Nishikura notes. “But when editing occurs, they may target a completely different set of genes.?

In recent years, Nishikura says, a growing number of scientists are discovering other links between RNA editing and the activities of different forms of non-coding RNA.

“We used to believe there were only a limited number of RNA editing sites,?she says, “but now we think there may be as many as 20,000 sites involving perhaps 3,000 genes. Interestingly, most of the editing sites correlate with non-coding regions of DNA, the so-called junk DNA.?

One reason for this, Nishikura and others speculate, may be that the majority of these non-coding regions are composed of repetitive sequences of DNA called transposons. The largest class of transposons, known as retrotransposons, have the remarkable ability to copy themselves into RNA, translate themselves back into DNA, and then reinsert themselves back into
'"/>

Source:The Wistar Institute


Page: 1 2 3

Related biology news :

1. Flick of whiskers helps tease out brains shadow signaling system
2. RNA project to create language for scientists worldwide
3. PCRM develops worlds first cruelty-free insulin assay
4. Harnessing microbes, one by one, to build a better nanoworld
5. Scientists journey to southern Africa to unravel the secret world of elephant communication
6. Scientists map the world for nature conservation
7. ORNL, UC Berkeley unravel real-world clues to Earths mysteries
8. Breakthrough: Scientists create worlds tiniest organic particles
9. Helping in a selfish world
10. Results of worlds first gene therapy trial for arthritis show approach safe, feasible
11. Researchers report breakthrough against world’s deadliest viruses
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Peering into the shadow world RNA

(Date:12/22/2014)... , Dec. 22, 2014  The 2014 Holiday ... biometrics industry as Acuity Market Intelligence reports that ... finally be open. Acuity forecasts that intensifying demand ... that incorporate biometrics will drive a global market ... biometric devices by 2020.   According ...
(Date:12/19/2014)... 2014 Research and Markets ( ... "iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... in July 2012, Apple introduced the fingerprint reading ... the only device of Apple incorporating such a ...
(Date:12/19/2014)... Research and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) ... Monitor: North America Perimeter Security Systems Market" report ... The North American perimeter security market ... from 2014 to 2019. Although the U.S. market holds ... is expected to grow at a higher ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3
... Italian Society for Ultrasound in Medicine and Biology (SIUMB) have ... of Ultrasound , starting in 2013 with Volume 16. Appearing ... journal of SIUMB. It will be available exclusively in electronic ... Elsevier. The Journal of Ultrasound deals with ...
... University of British Columbia and Oxford University researchers have ... of African elephant in the unforgiving Sahara desert, and ... the animals at risk. A two-year study, to ... tracked the elephants, migration with Global Positioning System (GPS) ...
... Athens, Ga. Fish play a far more important role ... according to researchers at the University of Georgia and Florida ... Ecology , they show that fish contribute more nutrients ... changes in the growth rates of the organisms at the ...
Cached Biology News:Springer will collaborate with the Italian Society for Ultrasound in Medicine and Biology 2Violence in Mali threatening survival of endangered elephants 2Fish have enormous nutrient impacts on marine ecosystems, study finds 2Fish have enormous nutrient impacts on marine ecosystems, study finds 3
(Date:12/19/2014)... Mass. , Dec. 18, 2014  Decision Resources ... dental biomaterial market will grow moderately through 2023 ... procedures and growing awareness of dental biomaterials all spur ... markets such as China and ... will bring dental procedures within reach for a larger ...
(Date:12/17/2014)... Based on the revenues gained from surgical ... dominated by four major players contributing to approximately ... include GE Healthcare (U.K.), Siemens AG (Germany), Philips ... Report Copy at http://www.marketsandmarkets.com/Market-Reports/surgical-imaging-market-210534462.html , The ... to its strong product portfolio, which includes its ...
(Date:12/17/2014)... Dallas, Texas (PRWEB) December 17, 2014 ... research on Global Quartz Tubing industry. For an ... information, definition, classification, application, industry chain structure, industry ... domestic quartz tubing industry has witnessed ... through a number of acquisitions. This report mentions ...
(Date:12/17/2014)... SPRING, Md. , Dec. 17, 2014  United ... two senior executive promotions as well as changes to ... Senior Executive Promotions United Therapeutics ... to President and Co-Chief Executive Officer and David ... Operating Officer.  In connection with these promotions, Dr. Rothblatt,s ...
Breaking Biology Technology:Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 2Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 3Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 2Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 3Global Refurbished Surgical Imaging Market by Product & Application is Estimated to Reach $1.25 Billion by 2019 - New Research Report by MarketsandMarkets 42020 Quartz Tubing Market: Global Development & Forecasts Analysis Now at DeepResearchReports.com 2United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 2United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 3United Therapeutics Corporation Announces Executive Promotions and CEO Compensation Change 4
... Unprecedented collaboration between industry, academia, government and health providers ... ... SAN DIEGO, June 16 The unique connectivity, talent ... sciences,companies to Scotland in recent years will be on show ...
... Deloitte,s leading position in the life sciences ... ... Deloitte has announced today an,agreement to acquire Recombinant Capital, Inc. ... in the,acquisition is Recap,s unique database that provides more than 1,500,subscribers ...
... BOSTON, June 16 Scimitar Equity, LLC issues ... VOQP), entitled,"Robust Pipeline of Niche, Cancer Therapies with ... at website: http://www.scimitarequity.com ., VioQuest Pharmaceuticals ... a recognized leader in the successful development of,novel ...
Cached Biology Technology:Scotland Showcased at BIO as Dynamic, Global Life Sciences Hub 2Scotland Showcased at BIO as Dynamic, Global Life Sciences Hub 3Deloitte Agrees to Acquire Recombinant Capital, A Leading Life Sciences Subscription Database and Advisory Services Firm 2Scimitar Equity, LLC Initiates Coverage Review of VioQuest Pharmaceuticals, Inc. 2
...
MAb to Verotoxin II (SLT-2a) Verotoxin II (Shiga-like) A subunit (SLT-2a)...
... BIP-NC H-IPMIK-OH Lyophilized solid. ... LIGHT. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A ... V5 (Cat. No. 196810) that serves as ... apoptosis (~200 μM). Purity: ≥97% by ...
... Chamber lid allows easy gel observation and provides ... easy set up between power supply and migration ... if the lid is removed at the migration ... Remote control can be easily operated in ...
Biology Products: