( e genomes of the 151 microorganisms stu...)Patterns in genome organization may partially explain how microbial cells work

"The analysis generated diagrams of psychedelically colored islands of statistically significant patterns floating in a sea of insignificant patterns," said Palsson, author of Systems Biology: Properties of Reconstructed Networks (Cambridge University Press, 2006). "Basically, it demonstrated that most bacterial genomes are highly organized. Our results demonstrate that there are significant evolutionary constraints that act upon genomes organization as well as upon genome content. That interplay between organization and function can't be ignored if we want to gain a better fundamental understanding of how a microbial cell works."