Navigation Links
Past illegal blood donation in China linked to hepatitis C virus infection

Research in a rural province of central China has documented that illegal blood donation practices led to high hepatitis C virus (HCV) infection rates in blood and plasma donors during the 1980s and early 1990s, and that failure to screen for HCV in transfusion recipients increased their risk of infection as well, according to an article in the November 15 issue of The Journal of Infectious Diseases, now available online.

Some blood donation facilities in rural China illegally pooled blood and reinfused compatible red blood cells to permit more frequent donations. Although government action has markedly curtailed such practices since the late 1990s, blood collection and banking methods in such settings still need to be monitored and improved, the article noted.

Researchers from the United States and China, including Han-zhu Qian, MD, PhD, of the University of Alabama at Birmingham, conducted a survey in 2003 among a random sample of 538 adult residents from 12 former commercial plasma-donating villages in Shanxi Province. Structured questionnaires were administered and blood samples tested for HCV antibodies. HCV rates were 8% in all participants, 28% in former plasma/blood donors, and about 3% in non-donors. Selling blood or plasma was the strongest independent predictor for HCV-positive findings. Receiving a blood transfusion was also independently associated with HCV; villagers who received blood transfusion had about 8 times the risk of HCV infection than those who had no history of blood transfusion.

Among the 538 villagers, 22 percent had a history of selling blood or plasma; from village to village, the rates ranged from 9 percent to 49 percent. The most common reasons for the practice were a need for money and being talked into it by other people. Villagers began to sell blood as early as in 1973 and as late as 1998; the main reasons for stopping were improved economic status, concern about health effects of blood drawing, abnormal liv er function tests or hepatitis, and shut-down of the illegal blood center.

The investigators concluded that unhygienic plasma donation and receipt of blood transfusion are strong risk factors for HCV infection in rural central China, and that improved blood collection and blood banking practices remain an urgent health priority. "Technical support and drugs are needed to assist these central Chinese provinces cope with the care and treatment needs of HCV patients," the investigators added.

In an accompanying editorial, Roger Y. Dodd, PhD, of the American Red Cross noted that the study is "a snapshot of past events and should not be taken to define the present circumstances." Nevertheless, it illustrates that "short cuts, shoddy practice, pursuit of the bottom line, and lack of oversight can have devastating outcomes, not only for patients but also for donors."


'"/>

Source:Infectious Diseases Society of America


Related biology news :

1. White blood cell waste disposal system plays critical regulatory role
2. Epstein-Barr virus protein crucial to its role in blood cancers
3. New insight into regulation of blood stem cells
4. Nano-bumps could help repair clogged blood vessels
5. First technology to remove prions that cause vCJD from blood launched
6. Breakthrough isolating embryo-quality stem cells from blood
7. Thai spice helps cut blood sugar swings
8. Study shows humans have ability to track odors, much like bloodhounds
9. Mad cow proteins successfully detected in blood
10. Unexpected lock and key mechanism found for the assembly of tumor blood vessels
11. Redesigned protein accelerates blood clotting
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/11/2017)... , April 11, 2017 No ... but researchers at the New York University Tandon ... of Engineering have found that partial similarities between ... systems used in mobile phones and other electronic ... The vulnerability lies in the fact ...
(Date:4/5/2017)... 2017  The Allen Institute for Cell Science today ... one-of-a-kind portal and dynamic digital window into the human ... first application of deep learning to create predictive models ... and a growing suite of powerful tools. The Allen ... future publicly available resources created and shared by the ...
(Date:4/4/2017)... April 4, 2017   EyeLock LLC , a ... the United States Patent and Trademark Office (USPTO) has ... the linking of an iris image with a face ... represents the company,s 45 th issued patent. ... very timely given the multi-modal biometric capabilities that have ...
Breaking Biology News(10 mins):
(Date:7/20/2017)... , ... July 20, 2017 , ... ... to make clinical trial sites and study participants truly unified. TrialKit, a native ... (FDA 21 CFR Part 11) research studies entirely on mobile devices. With TrialKit, ...
(Date:7/18/2017)... ... , ... G-CON today announced that it has received Notices ... Applications 14/858,857 and 13/669,785 both entitled Modular, Self-Contained, Mobile Clean Room. The U.S. ... of G-CON’s R&D investments and validate the G-CON platform as a novel way ...
(Date:7/17/2017)... ... , ... Whitehouse Laboratories is excited to announce that it ... of ISO 80369 standard test procedures. The ISO 80369 series of eight test ... With this recent expansion, Whitehouse Labs becomes one of the only facilities in ...
(Date:7/17/2017)... ... July 17, 2017 , ... Neurodevelopmental disorders (NDDs) are ... overlapping clinical features. The advancement of targeted next-generation sequencing (NGS) has been instrumental ... testing. , However, designing a custom panel for disease research requires hours ...
Breaking Biology Technology: