Navigation Links
PLoS Medicine publishes first trial of effect of male circumcision on HIV infection

The peer-reviewed results of the first trial of the effect of male circumcision on HIV infection, which some experts call "a landmark trial," will be published in PLoS Medicine on October 25. The trial found that circumcision reduced the rate of new infections among heterosexual men in South Africa by about 60%.

Because HIV infection rates are generally lower among African groups where circumcision is a traditional practice, compared with largely non-circumcised populations, researchers had suspected that circumcision might offer some protection against HIV transmission. However, because the lower infection rates in the circumcised groups might be due to some other difference between circumcised and uncircumcised populations, the only way to test whether circumcision has a protective effect is a randomized intervention study. Such trials are under way in Uganda and in Kenya but the trial reported in PLoS Medicine is the first to be completed, peer-reviewed, and published in a medical journal. The large protective effect of male circumcision observed has surprised many HIV experts, and it will be important to see whether the related studies under way confirm the results of this trial.

The trial, conducted by a team of French and South African researchers and sponsored by ANRS (the French National Agency of Research on AIDS), took place in the Orange Farm area near Johannesburg, where male circumcision in adulthood is a common but not universal practice.

The researchers offered young sexually active uncircumcised heterosexual men the chance to be circumcised and then monitored for HIV infection. The participants (3,274 men) were randomly allocated to two different groups--one group was immediately circumcised and the other group was to remain uncircumcised until after the completion of the trial 21 months later. The circumcised men were instructed to abstain from sexual activity for 6 weeks after the operation. The plan was t
'"/>

Source:Public Library of Science


Page: 1 2 3

Related biology news :

1. Recent breakthroughs in common adult leukemia highlighted in New England Journal of Medicine
2. Leukemia Drug Breakthrough Study In New England Journal Of Medicine
3. Transport System Smuggles Medicines Into Brain
4. Papers of DNA Pioneer and Nobel Laureate Francis Crick Added to National Library of Medicine’s Profiles in Science Web Site
5. Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance
6. FDA Works To Speed The Advent Of New, More Effective Personalized Medicines
7. Genpathway and Baylor College of Medicine Identify New Genes in Breast Cancer
8. Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines
9. $6.5 Million Grant for Microarray Center at Yale School of Medicine
10. Researcher at UGA College of Veterinary Medicine identifies new way of combating viral diseases
11. Smooth sailing: cruise ship virus tackled by UH, Baylor College of Medicine
Post Your Comments:
(Date:1/22/2015)... NXTD and NXTDW) a biometric authentication company focused on ... Wocket™ smart wallet at CES 2015 in Las Vegas ... the "11 Hot Products at CES" in a review published in Wired.com, ... Newseveryday.com and "The top 10 gadgets from CES 2015" by Danny ...
(Date:1/22/2015)... , Jan. 21, 2015  Analyst Report Issued by Small Cap ... report showed that planet-wide, transactions at merchants on the leading ... total number of credit, debit, and prepaid cards reached 6.54 ... victims of fraudulent card usage in 2012, and credit and ...
(Date:1/22/2015)... , Jan. 22, 2015 Research and Markets ... addition of the "Global Wearable Technologies Market ... Share, Overview, Trends and Forecast 2014-2020" report ... Technologies are smart devices that can be worn ...
Breaking Biology News(10 mins):CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 2Global Wearable Technologies Market and Applications, Opportunities, Industry Analysis, Segmentation, Size, Growth, Share, Overview, Trends and Forecast 2014-2020 2
... by a scientist at Fred Hutchinson Cancer Research Center ... common form of muscular dystrophy. The findings, published online ... the team,s series of groundbreaking discoveries begun in 2010 ... FSHD., The team, co-led by Stephen Tapscott, M.D., ...
... just catch our eyes, they catch those of pollinators like ... Because plants need to maximize the opportunity for pollinators to ... flowering can have profound effects on flower, fruit, and seed ... major driving forces of flowering are external factors such as ...
... at the U.S. Department of Energy,s (DOE) SLAC National ... of the electrons from xenon atoms, creating a "supercharged," ... The findings, which defy expectations and theory, could ... needed to study extreme states of matter or ward ...
Cached Biology News:Researchers discover 2 genetic flaws behind common form of inherited muscular dystrophy 2CSHL-led team discovers new way in which plants control flower production 2CSHL-led team discovers new way in which plants control flower production 3Study provides recipe for 'supercharging' atoms with X-ray laser 2Study provides recipe for 'supercharging' atoms with X-ray laser 3
(Date:1/22/2015)... 2015   GenoSpace , a precision medicine software company that ... broad use of genomic, imaging and other biomedical data in ... Michelle Munson , CEO of Aspera, an IBM Company, to ... http://photos.prnewswire.com/prnh/20150122/170713 "We are pleased to ...
(Date:12/24/2014)... NEW YORK , Dec. 24, 2014 PlasmaTech ... care in critical areas, announced the closing of an underwritten ... to purchase up to an aggregate 3,500,000 shares of common ... $.01 per warrant.  The warrants have a per share exercise ...
(Date:12/24/2014)... GMO corn cases filed across the United States, ... of being consolidated in a Kansas federal court for pretrial ... 162 Corn Litigation, MDL No. 2591 in the U.S. District ... Syngenta GMO corn multidistrict litigation (MDL) has been handed over ...
(Date:12/24/2014)... New York (PRWEB) December 23, 2014 According ... the Long Island Affiliate of ITRA Global, the national office ... but steady recovery. This is evidenced by the third ... strong stock market. Low energy costs have held inflation ...
Breaking Biology Technology:GenoSpace Expands Board with Appointment of Michelle Munson 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 2PlasmaTech Biopharmaceuticals, Inc. Announces Closing of Public Offering 3Carey Danis & Lowe Reports on Syngenta GMO Corn Transfer Order 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 2ITRA Global Reports Long Island Is Out of Sync With The National Office Market 3
... GPRO ) announced today that the Company will ... 31, 2008 at approximately,4:00 p.m. Eastern Time (ET). The ... p.m. ET. Hank Nordhoff, chairman and chief,executive officer, and ... will host the call., The conference call will ...
... merit and part of its overall strategy to, cripple PSC, force PSC to ... for failing to provide funding to ... PSC., -- ... FDA approval for its lead vaccine product, FluBlok, ...
... , - 1st Half-Year Sales Up 16%, - Revision Upwards of 2008 Sales Growth Guidance: (greater than or equal,to)12%, EUR millions ... 2008 08/07 ... ... 20.5 72 23.2 72 13 26.8 71 15 ...
Cached Biology Technology:Gen-Probe Announces Webcast of Second Quarter 2008 Earnings Conference Call 2Protein Sciences Responds to Emergent BioSolutions Lawsuit 2Protein Sciences Responds to Emergent BioSolutions Lawsuit 3Protein Sciences Responds to Emergent BioSolutions Lawsuit 4Protein Sciences Responds to Emergent BioSolutions Lawsuit 5Stallergenes: Q2 2008 Sales up 18% Revision Upwards of 2008 Sales Growth 2
pH-insensitive fluorescence (pH 2-12)...
PPOX Immunogen: PPOX (AAH02357, 378 a.a. ~ 478 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
KRIT1 Immunogen: KRIT1 (NP_004903, 637 a.a. ~ 737 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
Rabbit polyclonal to MAP3K12 ( Abpromise for all tested applications). Antigen: Synthetic peptide conjugated to KLH from the C-terminal region of human MAP3K12 Entrez Gene ID: 7786 Swiss ...
Biology Products: