Navigation Links
PET imaging shows young smokers quick benefit of quitting

The early stages of coronary artery disease in young smokers can be reversed quickly if they choose to put out their cigarettes for good, according to a positron emission tomography (PET) imaging study in the December Journal of Nuclear Medicine.

"I believe this is the first PET study that shows abnormal coronary function is reversible after only one month of smoking cessation," said Nagara Tamaki, a professor and chair of the nuclear medicine department at Hokkaido University in Sapporo, Japan. "Smoking cessation normalized abnormal coronary artery function, thus supporting its value in preventing heart disease in young adults," he explained. "In addition, this is an important report with PET imaging that shows abnormal coronary artery function can be measured by coronary blood flow and flow response to cold stimulation (also called 15O-water PET) in healthy young smokers," noted the co-author of "Smoking Cessation Normalizes Coronary Endothelial Vasomotor Response Assessed With 15O-Water and PET in Healthy Young Smokers." Researchers from the Japanese university also noted that improvement was "preserved" six months after the study's subjects stopped smoking, "supporting the value of smoking cessation for prevention of coronary artery disease particularly in the young," said Tamaki.

"This study provided a noninvasive look at the early stages of coronary artery disease in smokers and the recovery time of coronary endothelial dysfunction after giving up cigarettes," indicated Tamaki. Coronary endothelial dysfunction occurs when the heart's blood vessels aren't flexible enough to expand in response to increased blood flow. Smoking can damage the endothelium—the innermost layer of the artery—and over time, plaques can narrow coronary arteries, allowing less blood to flow to the heart muscle. Rupture of these plaques may result in a stroke, heart attack and death.

It's generally known that the risk of death from coronary artery disease is u p to six times higher in smokers than in nonsmokers, and about half of all smokers who continue to smoke will end up dying from a smoking-related illness. Cigarette smoking is the leading cause of preventable death in the United States, accounting for 438,000 deaths annually (about one of every five deaths). Since coronary endothelial dysfunction is both "a significant predictor of cardiovascular events"—and reversible—its early detection is important, said Tamaki. PET—a diagnostic imaging test that measures metabolic activity and generates images of organ or tissue function?will continue to provide insight into coronary risk analysis and risk management (such as smoking cessation and lowering one's cholesterol)," he added.

In the Hokkaido University study, researchers examined the effects of smoking cessation on coronary endothelial dysfunction in 15 young male adults (in their twenties and thirties) with no other heart diseases or cardiovascular risk factors (other than smoking). The young smokers, who smoked an average of 20 cigarettes a day, agreed to stop for at least six months. Myocardial (heart) blood flow was measured both at rest and during stimulation induced by a cold pressor test by using PET with the oxygen tracer called 15O-water. Additional research is necessary, said Tamaki. "We would like to compare the current information with data from middle-aged smokers to see whether such response after smoking cessation may be seen in an older generation. Also, it would be nice to see the reversibility in young smokers associated with other risk factors, such as diabetes and obesity," he said.
'"/>

Source:Society of Nuclear Medicine


Related biology news :

1. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
2. Duke engineers develop new 3-D cardiac imaging probe
3. Confocal imaging promises early detection of skin cancer
4. Newer imaging techniques may lead to over-treatment
5. Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton
6. Microscopic brain imaging in the palm of your hand
7. New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
8. Purdues gold nanorods brighten future for medical imaging
9. PET imaging reveals the immune system at work
10. New technique puts brain-imaging research on its head
11. T-rays: New imaging technology spotlighted by American Chemical Society

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/19/2017)... New York , April 19, 2017 ... competitive, as its vendor landscape is marked by the ... the market is however held by five major players ... Safran. Together these companies accounted for nearly 61% of ... of the leading companies in the global military biometrics ...
(Date:4/13/2017)... UBM,s Advanced Design and Manufacturing event in ... and evolving technology through its 3D Printing and Smart ... the expo portion of the event and feature a ... on trending topics within 3D printing and smart manufacturing. ... will take place June 13-15, 2017 at the Jacob K. ...
(Date:4/11/2017)... Apr. 11, 2017 Research and Markets has ... report to their offering. ... The global eye tracking market to grow at a CAGR of ... Eye Tracking Market 2017-2021, has been prepared based on an in-depth ... market landscape and its growth prospects over the coming years. The ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... DuPont Pioneer ... that they have entered into a multiyear collaboration to identify and characterize novel ... additional tools for gene editing across all applications. , Under the terms of ...
(Date:10/11/2017)... (PRWEB) , ... October 11, 2017 , ... ... Foundation President Andi Purple announced Dr. Suneel I. Sheikh, the co-founder, CEO ... ASTER Labs ), Inc. has been selected for membership in ARCS Alumni ...
(Date:10/11/2017)... , Oct. 11, 2017  VMS BioMarketing, a leading ... a nationwide oncology Clinical Nurse Educator (CNE) network, which will ... need for communication among health care professionals to enhance the ... nurses, office staff, and other health care professionals to help ... breast cancer. ...
(Date:10/10/2017)... CALIF. (PRWEB) , ... October 10, 2017 , ... San ... part of its corporate rebranding initiative announced today. The bold new look is ... reach, as the company moves into a significant growth period. , It will also ...
Breaking Biology Technology: