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PANTHER Protein Classification System Database 5.0

PANTHER, a protein classification system from Applied Biosystems, got updated to version 5.0. Proteins are classified by family, molecular and biological function (GO ontology) and known pathways. Its main use is probably microarray analysis - it incorporate automated GO surrepresentation analysis with graphical output. Best of all, its available freely. A paper describing the Database is available freely in the Nucleic acids research Journal.

Applied Biosystems (NYSE:ABI), an Applera Corporation business, today announced the latest release of the PANTHER?system database of protein families, subfamilies, functions and pathways. Enhancements to the latest version, Panther 5.0, include interactive resources for associating protein families with their biological pathways, as well as new tools for analyzing gene expression data in relation to molecular functions, biological processes, and pathways. The PANTHER system database is publicly available without restriction at http://panther.appliedbiosystems.com. Today’s announcement coincides with the publication of a peer-reviewed paper describing the latest version of the PANTHER system database in the January 2005 edition of Nucleic Acids Research. In conjunction with this publication, PANTHER system will become part of the European Bioinformatics Institute’s InterPro database beginning in February, which provides an integrated view of the most commonly used protein databases through an intuitive interface for text- and sequence-based searches. “The PANTHER system provides scientists with a unique resource for gene function prediction and analysis based on a combination of advanced bioinformatics and manual data curation,?said Paul D. Thomas, Senior Director of Computational Biology for Applied Biosystems, Primary Investigator for the development of the PANTHER system, and lead author of th
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Source:Applied Biosystems Press Release


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