Navigation Links
Outsmarting the smartie bug

ts against 82% of infections in children under five years of age in the UK. This will soon be given to UK children under the age of two. A second, PPV, recognizes 23 capsule types and protects against 96% of the UK's strains but is not effective in infants and is mainly used to protect the elderly.

S. pneumoniae usually lives harmlessly in the air passages and in the first year of life most people are likely to have 'carried' at least one strain. It is passed from person to person by sneezing and other aerosols. However, it occasionally passes from the airways to invade other tissues. This can lead to any one of a range of diseases including meningitis and infections of the sinuses, ear, lungs and blood. Why it switches to become invasive is not known.

The team sequenced all genes required to make all 90 forms of the capsule (more than 1,800,000 letters of genetic code), determined their function and studied their evolution. The work gives the most complete understanding of capsule production in any bacterial species.

The new vaccine will protect children from many of the most common serotypes but monitoring is needed to check whether other serotypes start to cause some disease. It is known that pneumococci can switch their capsular polysaccharide and so, if an invasive strain changes its coat to a form not recognised by the vaccine, it might start to become more prevalent and cause disease.

The catalogue of capsules from all known strains will help in the development of new techniques for monitoring changes in capsule type so researchers can look out for such capsule switching.

"The new vaccine that will be given to UK children is very effective at protecting against serious pneumococcal disease, but it does not protect against disease caused by the rarer serotypes," said Brian Spratt, Professor of Microbiology at Imperial College and a co-author of the study. "The catalogue of capsular genes will help us develop better met
'"/>

Source:Public Library of Science


Page: 1 2 3

Related biology news :

1. New insight into people who see colors in letters and numbers
2. Alaskan puzzles, monitoring provide insight about North Pacific salmon runs
3. New insight into regulation of blood stem cells
4. New insight into autoimmune disease: Bacterial infections promote recognition of self-glycolipids
5. New insights into how Huntingtons disease attacks the brain
6. Gambling monkeys give insight into neural machinery of risk
7. Structures of marine toxins provide insight into their effectiveness as cancer drugs
8. Flies on speed offer insight into the roles of dopamine in sleep and arousal
9. Grasshopper love songs give insight into sensory tuning
10. Studies on human genome variation provide insight into disease
11. Study provides insight into cellular defenses against genetic mutation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Outsmarting the smartie bug

(Date:9/16/2014)... available in Spanish . ... study published in the Journal of Cell Biology ... for proper cell division , At this very moment thousands ... the mechanism by which the body repairs damaged tissues and ... complex process known as "mitosis", during which the cell duplicates ...
(Date:9/16/2014)... PALM BEACH GARDENS, Fla. , Sept. 16, ... provider of biometric identity management solutions, announced today ... handheld solution designed to authenticate the identity of ... The Android-based Verifier Sentry rapidly reads ... the credential holder,s ID by matching the biometric ...
(Date:9/15/2014)... populations may continue to drop in French Guiana, despite ... National de la Chasse et de la Faune Sauvage ... data retrieved from camera traps in the Nouragues National ... data to current harvest rates in the region., "In ... Guiana," said Matthias Tobler, a scientist with the San ...
Breaking Biology News(10 mins):Unraveling cell division 2Unraveling cell division 3Cross Match Launches New Identity Management Handheld Solution 2
... underlying brain skills needed to think, remember and learn are ... fact of life for most older Americans. ... critically important for lessening declines in mental performance as people ... efforts aimed at preventing or delaying cognitive decline, dietary modifications ...
... on biomarkers of cardiovascular disease: implications for heart-healthy diets," ... , examined 26 clinical studies and two meta-analyses to ... Of the probiotics examined, L. reuteri NCIMB 30242 ... (TLC) dietary requirements by: , Significantly ...
... , Fires in and around Snowy River National Park in ... (MODIS) aboard the Aqua satellite on February 06, 2014. Actively ... red. Hot, dry, windy conditions in Victoria have been ... territory. The fires in this image are located in ...
Cached Biology News:Nutritional supplement improves cognitive performance in older adults, study finds 2Nutritional supplement improves cognitive performance in older adults, study finds 3Heart health through gut health 2
(Date:9/15/2014)... The very idea of fibers made of carbon nanotubes is ... literally. , The single-walled carbon nanotubes in new fibers created ... through a process designed by chemist Angel Mart and his ... reported its results this month in the journal ACS ... they,re drawn together into a fiber. , Left to their ...
(Date:9/15/2014)... MORRISVILLE, NC (PRWEB) September 15, 2014 ... newly developed deep imaging OCT system for the optical ... , The EnvisuTM S4410 SDOCT for Contact ... measurements for standard and high complexity contact lens, IOL ... allows imaging of a complete contact lens immersed in ...
(Date:9/15/2014)... BOISE, Idaho , Sept. 15, 2014  iVinci ... and only comprehensive Patient Revenue Management system, branded as ... The company also announced the launch of a new ... Portal that provides an easy and convenient way for ... plans for balances owed by them and their families. ...
(Date:9/15/2014)... The chemistry, taste, and health effects of tea can vary ... the nonprofit American Botanical Council (ABC). Recent research by ... on the phytochemical compounds in tea ( Camellia sinensis ) ... in the Yunnan province of southwestern ... future of medicinal botanicals. Dr. Ahmed,s report on ...
Breaking Biology Technology:Rice rolls 'neat' nanotube fibers 2Rice rolls 'neat' nanotube fibers 3Bioptigen Introduces Deep Imaging OCT System for Contact Lens Metrology 2iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 2iVinci Health Raises $5M to Fuel National Expansion, Announces Launch of Personal Finance Portal for Healthcare 3Tea Taste and Quality Affected by Climate Change 2Tea Taste and Quality Affected by Climate Change 3Tea Taste and Quality Affected by Climate Change 4
... Switzerland, Jan. 5, 2012   Selexis SA ... Ph.D., will present at the Biotech Showcase 2012 Conference ... Conference in San Francisco, CA. Dr. Fisch ... Growth Investment" to prospective investors and corporate partners on ...
... Calif., Jan. 5, 2012  AtheroNova, (OTCQB: AHRO) ("AtheroNova"), a biotech ... regress atherosclerotic plaque, announced today that it has appointed Johan ... of Directors of the Company effective January 3, 2012. Mr. ... Audit and Medical Committees of the Board. ...
... 2012 CMC Biologics, a leading biopharmaceutical contract ... No. US 2,171,034 B1 covering a method for ... culture bioreactors. The invention is designed to optimize ... fermentation process, wherein the bioreactor (fermenter) has an ...
Cached Biology Technology:Selexis SA to Present at Biotech Showcase 2012 2AtheroNova Announces a New Board Member 2AtheroNova Announces a New Board Member 3CMC Biologics Strengthens its Innovative Biomanufacturing Technology Portfolio in Continuous Perfusion Systems 2
Request Info...
Kit containing positive control DNA all parts of the HIV-1 genome, HIV-1 negative control DNA, Primers SK38, SK39, SK19...
Contains 0.2 g/L EDTA4Na in phosphate-buffered saline....
Immunochemistry 1 & 2...
Biology Products: