Navigation Links
Orange, grapefruit juice for breakfast builds bones in rats

It may sound like Saturday cartoons: a strong-boned rat that can't be broken. But a couple of Texas researchers say the real hero is citrus juice.

Orange and grapefruit juice regularly given to lab rats prevented osteoporosis, long considered an unavoidable aging disease in which bones become more likely to break, according to a study by Texas A&M University's Vegetable and Fruit Improvement Center researchers. The article was published in Elsevier's Nutrition journal.

Osteoporosis affects about 2 million men and 8 million women in the United States, according to the National Osteoporosis Foundation. Nationally, about 1.5 million hips, vertebras and wrists break each year as a result, said Dr. Bhimu Patil, director of the center at Texas A&M in College Station.

"It's a silent disease of aging. But if we can maintain our bone strength, maybe we'll be able to prevent it," Patil noted.

For the study, 36 males rats were included for two months in the lab of Dr. Farzad Deyhim, professor of human and animal nutrition at Texas A&M- Kingsville. Half of the rats were a control group that continued life as usual. The others were castrated and then treated in one of three ways: no additional diet change; diet included orange juice; or, diet included grapefruit juice.

Castration was necessary, the researchers said, because the hormone testosterone is known to reduce antioxidants.

"This is a problem with aging men, because, the level of testosterone decreases as men age," said Deyhim, adding a similar study on female rats has begun.

Deyhim said fresh grapefruit or orange juice - mixed with sodium bicarbonate to neutralize acidity - was given to the rats each morning.

"They drank it with no problem, every morning," Deyhim said. "They drank more fresh juice than I did during that period."

Deyhim said the juice study was followed by a similar test with orange and grapefruit pulp, and although the r esults of that research has not been published yet, it too showed enhanced bone density.

He said the team will now examine the rats' bones at the cellular level "to see what caused that improvement in the bone." "A reduction in bone density is caused when there is an increase in oxidants. In these studies, both grapefruit juice and orange juice increased antioxidants in the rats' systems," Patil said. "So that is the benefit since oxidants damage bone cells.

"There are about 400 compounds in citrus," he said. "So we need to find out which compound in citrus caused this."

Patil suspects "limonoid,"a natural citrus compound, which has been increasingly studied for its potential to prevent various human diseases. Limonoids will be the next phase of the study, but there are at least 40 different ones, Patil cautioned.

"This study backs up our thoughts about the value of citrus," Patil said, noting that until researchers completely understand the interaction of grapefruit juice and certain medications, a person should ask a doctor.

"In general, people should eat a variety of all the colors (in food) to get all of the beneficial compounds," Patil added. "And eat fresh."


Source:Texas A&M University - Agricultural Communications

Related biology news :

1. Study identifies substances in grapefruit juice that interact dangerously with some drugs
2. Despite acidity, orange juice could still be a source of foodborne disease
3. 100 percent juices found as beneficial to health as fruits and vegetables
4. New bacteria test could improve quality of fruit and vegetable juice
5. Signaling protein builds bigger, better bones in mice
6. New MRI technique quickly builds 3-D images of knees
7. Study shows enzyme builds neurotransmitters via newly discovered pathway
8. Lithium builds gray matter in bipolar brains, UCLA study shows
9. University of Manchester makes made-to-measure skin and bones a reality using inkjet printers
10. Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.
11. NC State scientist finds soft tissue in T. rex bones
Post Your Comments:

(Date:10/12/2015)... Hoyos Labs , ... will introduce its new biometric four-finger (4F) ... providing an unprecedented level of security / ... new biometric standard for secure transactions (BOPS). ... financial services to healthcare are implementing Hoyos, ...
(Date:10/8/2015)... 8. Oktober 2015 Die Track ... Unternehmen des Bereiches Tracking, hat heute bekannt ... Gefängnisbehörde Virginias (Department of Corrections – DOC) ... für alle Strafen geliefert werden, die der ... Präsident für den Amerikanischen Kontinent der Track ...
(Date:10/6/2015)... MATEO, Calif. , Oct. 6, 2015 /PRNewswire/ ... company, today announced enhancements to its software portfolio ... expression analysis kit for differential expression in eukaryotes. ... Platform, which is a cloud-based genomic analysis solution ... advance scientific discovery from next-generation sequencing efforts. ...
Breaking Biology News(10 mins):
(Date:10/12/2015)... cell surface marker detection market ... to a new report by Grand View Research, Inc. This ... of oncology diseases and other cell-associated disorders. --> ... USD 6.49 billion by 2022, according to a new report ... be attributed to rise in incidence of oncology diseases and ...
(Date:10/12/2015)... /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ:  AEZS) (TSX: AEZ) ... and commercializing novel treatments in oncology, endocrinology and women,s ... , the Company,s former Senior Vice President, Chief Financial ... Quebec City office.  David ... of the Company commented, "After a comprehensive review, the ...
(Date:10/12/2015)... -- LabStyle Innovations Corp. (OTCQB: DRIO), ... its Medical Director, Dr. Moshe Kamar , will ... EAI International Conference on Wireless Mobile Communication and Healthcare ... and wireless technologies," the conference will take place in ... - 16, 2015. The conference is endorsed and organized ...
(Date:10/12/2015)... , Oct. 12, 2015 VolitionRx Limited ... completed clinical study of its NuQ ® blood-based test ... online issue of Clinical Epigenetics , the official journal ... in collaboration with Lund University, ... , MD, PhD, Professor of Surgery and Vice-Dean, Faculty of ...
Breaking Biology Technology: