Navigation Links
One therapeutic dose of radiation causes 30 percent spongy bone loss in mice

l cancer increased the risk of fracture by 200%, he said.

Astronauts lose 2% of bone mass for each month they are exposed to the effects of microgravity. So far, astronauts have not been exposed to the increased radiation of outer space, but that will change when they undertake a proposed 30-month trip to Mars, Bateman said. NASA has focused on radiation's cancer-causing properties and its ability to compromise the central nervous and immune systems. But the effect on bone health is an unexamined concern.

The murine (mouse) model such as the one in this study provides a way to study the physiological effects of radiation using controlled experiments. Clinical studies of people who undergo radiation to treat cancer are limited because of the complicating factors of the illness itself and the chemotherapy which often accompanies it. "You can't study this in people, so having a well-defined animal model is important," Bateman said.

Study focuses on four types of radiation

In the current study, the mice received a single 2 Gray (Gy) dose, which is comparable to the single dose of 1-2 Gy that human cancer patients receive. However, cancer patients receive a series of doses over the course of therapy, totaling 10-70 Gy. (The amount of radiation in a Gy varies, because it is calculated based on the recipient's weight.)

The mice were divided into five groups. The control group received no radiation. Each of the remaining four groups received a different type of radiation: gamma, proton, ion or carbon. Those exposed to the carbon radiation suffered 39% spongy bone loss; proton, 35%; ion, 34%; and gamma, 29%. The loss of spongy connections in the four groups ranged from 46-64%, he said.

Cancer patients typically receive either gamma or, less commonly, proton radiation. Astronauts on a Mars mission are expected to receive extended periods of low-dose radiation of multiple types, including protons and heavy ions, Bate
'"/>

Source:American Physiological Society


Page: 1 2 3

Related biology news :

1. Study reveals candidate targets for anti-retroviral therapeutics
2. Tetanus toxin found to have therapeutic properties
3. Dendritic cells offer new therapeutic target for drugs to treat MS and other autoimmune disease
4. Greasing interferons gears may pave way to greater therapeutic benefits, fewer side effects
5. Anthrax inhibitor counteracts toxin, may lead to new therapeutics
6. Nano-particles effective in killing cancer with one-two punch of chemotherapeutics
7. T cells activated to fight HIV basis for dendritic cell therapeutic vaccine
8. Small molecule dervived from Rb2/p130 could act as cancer therapeutic
9. Gene therapy may protect normal tissues during radiation retreatment for lung cancer
10. Jefferson researchers find nanoparticle shows promise in reducing radiation side effects
11. Gene therapy protects mice from the effects of whole-body irradiation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: One therapeutic dose radiation causes percent spongy bone loss mice

(Date:8/10/2015)... and TELTOW, Germany , August 10, ... (SMI), a world leader in Eye Tracking Technology for ... its OEM Eye Tracking Platform for integration into all ... contains reference designs for seamless integration of eye tracking ... reality HMDs and augmented reality smart glasses. Omnivision,s leading ...
(Date:8/6/2015)... , Aug. 6, 2015  Today, U.S. Congressman ... Crossmatch ™ to learn firsthand how Silicon ... data. Crossmatch is a world leader in multi-factor ... expertise are helping federal agencies and commercial organizations ...   "The vast majority of network ...
(Date:8/6/2015)... 2015 Synaptics Inc. (NASDAQ: SYNA ... today announced collaboration with Microsoft on biometric fingerprint ... leveraged Synaptics, deep expertise in human interface which ... Through stringent testing, Synaptics, advanced image sensing ... Precision TouchPad (PTP) specification empowering OEMs with Windows ...
Breaking Biology News(10 mins):SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3Rep. Honda to Visit Crossmatch in Redwood City 2Synaptics Chosen for Human Interface Co-Development on Windows 10 2
... (Garrison, NY) "All natural," the way Mother Nature intended it," "it,s ... what we call natural does a lot of work in our ... really behind it? What do we mean when we "appeal to ... Those are some of the questions taken up in The ...
... American Association for Cancer Research has been the premier ... This year, Elizabeth H. Blackburn, Ph.D., the immediate ... laureate, will chair the Second AACR Conference on Frontiers ... research leaders from across the globe to encourage and ...
... the US are testing biofilter systems as a viable ... the atmosphere. The technology could reduce the overall impact ... in the current issue of the International Journal ... smaller, old landfill sites generates a slow trickle of ...
Cached Biology News:New book on the meaning of nature connects vacations, corn, baseball 2Biofilters reduce carbon footprint of old landfill sites 2
(Date:8/31/2015)... (PRWEB) , ... August 31, 2015 , ... ... together the world's most successful food and beverage processors, equipment manufacturers and leaders ... in product inspection and industrial weighing and formulation for manufacturers of bakery and ...
(Date:8/30/2015)... , England , August 31, 2015 ... die 51-jährige Wartezeit   einer Frau   für chirurgische ... im Alter von 7-90   werden für ... Programm soll 1200 Frauen behandeln und die Anzahl ... Astellas gab heute bekannt, dass  ...
(Date:8/28/2015)... ... August 28, 2015 , ... Proove Biosciences , a ... International Spine Intervention Society’ s 23rd Annual Scientific Meeting (ASM). The ASM ... a focus on evidence-based research and clinical application, the event gathered industry thought ...
(Date:8/28/2015)... ... August 28, 2015 , ... ... orthopedic surgeon, Wade McKenna, DO, announced today that the use of sterile, dehydrated ... in complete healing of an otherwise non-healing surgical knee wound. , The case ...
Breaking Biology Technology:METTLER TOLEDO Hosts Food Safety Educational Center at 2015 PROCESS EXPO 2Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 2Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 3Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 4Über 550 Frauen, deren Leben durch "Action on Fistula" transformiert wurde 5Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 2Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 3Proove Biosciences Presents New Research Study at the International Spine Intervention Society’s Annual Scientific Meeting 4Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 2Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 3Dallas-Fort Worth Stem Cell Researchers Use Amniotic Tissue To Successfully Treat Non-Healing Surgical Wound 4
... CHICAGO -- Lots of us in the Midwest technology workplace -- ... industry and beyond -- found ourselves in a new and unpleasant ... jobs that we wouldnt have remotely considered in the past (at ... at a less-than-sensational company because the job market was so rocky. ...
... pop biotech quiz to see if you know your biotech history and ... many of these companies still exist? How many of them are ... of you will get at least three of the six companies right ... Here is the answer: , Genentech Biogen Genex ...
... embryonic stem cells in a UW-Madison lab. Photo courtesy ... ballot this November may affect Wisconsin's leadership in the ... passed, the Stem Cell Research and Cures Initiative ... tax-free state bonds over 10 years for embryonic stem ...
Cached Biology Technology:Ten reasons to flee your Midwest technology employer 2Ten reasons to flee your Midwest technology employer 3Ten reasons to flee your Midwest technology employer 4Ten reasons to flee your Midwest technology employer 5The birth of biotech: San Francisco, Boston, Geneva or Chicago? 2The birth of biotech: San Francisco, Boston, Geneva or Chicago? 3The birth of biotech: San Francisco, Boston, Geneva or Chicago? 4The birth of biotech: San Francisco, Boston, Geneva or Chicago? 5The birth of biotech: San Francisco, Boston, Geneva or Chicago? 6The birth of biotech: San Francisco, Boston, Geneva or Chicago? 7Referendum may pull California to the forefront of stem cell research 2Referendum may pull California to the forefront of stem cell research 3Referendum may pull California to the forefront of stem cell research 4Referendum may pull California to the forefront of stem cell research 5
... Rabbit polyclonal to ErbB 2 ... Abpromise for all tested applications). ... peptide: AENPEYLGLDVPV conjugated to KLH, corresponding ... of Human c-ErbB2 ...
Recognizes TWIK-2. Does not cross react with any other known proteins....
Potassium Channel kv3.2...
Sheep polyclonal to ErbB 2 ( Abpromise for all tested applications). Antigen: Recombinant full length c-ErbB2 protein (Human). Entrez GeneID: 2064 Swiss Protein ID: P04626...
Biology Products: