Navigation Links
One species, many genomes

Faster growth, darker leaves, a different way of branching - wild varieties of the plant Arabidopsis thaliana are often substantially different from the laboratory strain of this small mustard plant, a favorite of many plant biologists. Which detailed differences distinguish the genomes of strains from the polar circle or the subtropics, from America, Africa or Asia has been investigated for the first time by research teams from Tübingen, Germany, and California led by Detlef Weigel from the Max Planck Institute for Developmental Biology. The results were surprising: The extent of the genetic differences far exceeds the expectations for such a streamlined genome, as the scientists write in this week’s edition of Science magazine.
Arabidopsis plants from different geographical origins differ in many traits (the background shows schematically sequence variation in the DNA of these plants).


To track down the variation in the genome of the different Arabidopsis strains, the researchers compared the genetic material of 19 wild strains with that of the genome of the lab strain, which was sequenced in the year 2000. Using a very elaborate procedure, they examined every one of the roughly 120 million building blocks of the genome. For their molecular sleuthing they used almost one billion specially designed DNA probes. "All together, these probes would have seven times the length of human genome," illustrates Weigel the extent of the project. The data were evaluated with several specially designed statistical methods, including a variant of machine learning.

The result of this painstaking analysis: on average, every 180th DNA building block is variable. And about four percent of the reference genome either looks very different in the wild varieties, or cannot be found at all. Almost every tenth gene was so defective that it could not fulfill its normal function anymore!

Results such as these raise fundamental questions. For one, they
'"/>

Source:Max-Planck-Gesellschaft


Page: 1 2 3

Related biology news :

1. Same mutation aided evolution in many fish species, Stanford study finds
2. Reservoirs may accelerate the spread of invasive aquatic species, researchers say
3. First surveys of Tanzanian mountains reveal 160+ animal species, including new & endemic
4. Multiple Campylobacter Genomes Sequenced
5. Big differences in duplicated DNA distinguish chimp and human genomes
6. Double trouble: Cells with duplicate genomes can trigger tumors
7. Three deadly parasite genomes sequenced
8. Researchers predict infinite genomes
9. Breaking the mold: Research teams sequence three fungus genomes
10. DOE JGI releases IMG 1.5 with curated archaeal genomes
11. Whats shaped like a pear and has 2 genomes? Check the pond
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: One species many genomes

(Date:7/9/2015)... , July 9, 2015  Synaptics Inc. (NASDAQ: SYNA ... today that it will report financial results for the ... 30, 2015 after the close of market. The company ... investors at 2:00 p.m. PT (5:00 p.m. ET), during ... To participate on the live call, analysts and investors ...
(Date:7/8/2015)... , July 8, 2015 Summary ... and the fourth most fatal, with a mortality rate ... poor prognosis of pancreatic cancer patients has highlighted a ... which is not being met by the current market. ... array of products with varying molecule types and mechanisms ...
(Date:7/7/2015)... Research and Markets ... the "Capacitive Fingerprint Sensors Patent Landscape" ... date, fingerprint sensing technology is the most reliable ... well developed. This patent landscape focuses on fingerprint ... domain of capacitive fingerprint sensors is closely linked ...
Breaking Biology News(10 mins):Synaptics to Report Fourth Quarter, Fiscal Year 2015 Results on July 30 2Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 2Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 3Worldwide Capacitive Fingerprint Sensors Patent Landscape Market Report 2015-2020 - Main IP Holders include Seiko Epson, AuthenTec, Sony and STMicroelectronics 2
... are consuming at least double the recommended amount of salt ... at the University of Gothenburg and Sahlgrenska University Hospital. "It,s ... and something needs to be done about it. We can ... salt intake later on in life, in the form of ...
... discovered a chemical compound in a sponge off Palau, ... shown anticancer, antibacterial, and antifungal pharmaceutical promise. But that ... This compound, called Palau,amine, is so chemically complex ... laboratory became the most hotly pursued synthetic chemistry goal ...
... birds can help pinpoint likely carrier species and geographic ... to enter North America, according to new U.S. Geological ... pathogenic avian influenza H5N1 (HPAI H5N1) virus in Eurasia ... transported among continents by migratory birds has resulted in ...
Cached Biology News:Scripps Research team wins global race to achieve landmark synthesis of perplexing natural product 2Scripps Research team wins global race to achieve landmark synthesis of perplexing natural product 3Scripps Research team wins global race to achieve landmark synthesis of perplexing natural product 4New research findings can improve avian flu surveillance programs 2
(Date:8/3/2015)... MARIETTA, Ga. , Aug. 3, 2015  MiMedx ... medicine company utilizing human amniotic tissue and patent-protected processes ... the Wound Care, Surgical, Orthopedic, Spine, Sports Medicine, Ophthalmic ... will present at the 35 th Annual Canaccord|Genuity ...  Parker H. "Pete" Petit, Chairman and CEO, William ...
(Date:8/3/2015)... Delaware , August 3, 2015 ... in the commercialization of its Bio-electrical Signal Therapy device ... noninvasive treatment of hard to heal chronic wounds, today ... agreement with Chemipal, an Israeli distributor specializing in medical ... device. Chemipal is a 70 years old, ...
(Date:7/31/2015)... VEGAS , July 31, 2015 ... seek resources that help them drive positive health ... a vital source of patient care in their ... annual tradeshow and conference, AmerisourceBergen announced a ... its Pharmacy Services Administration Organization and help independent ...
(Date:7/30/2015)... 2015 AACC welcomed thousands of medical ... Annual Meeting & Clinical Lab Expo in ... meeting showcased revolutionary advancements in clinical testing technology ... providers to diagnose patients quickly and accurately and ... As of Wednesday, July 29, more ...
Breaking Biology Technology:MiMedx To Present At 35th Annual Canaccord|Genuity Growth Conference 2E-QURE Corp Signs Second Distribution Agreement in Israel 2E-QURE Corp Signs Second Distribution Agreement in Israel 3AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 2AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 3Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 2Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 3Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 4
... , , , High-quality ... efficient gene silencing in eukaryotic cell culture by targeting complementary , ... , gene silencing in functional genomics studies. Now, ... service that includes a range of modifications , ...
... , , Stefanie Schrer, Werner Wittke,* and , ... Germany , , * Leica ... , Laser microdissection (LMD) provides a powerful , ... This eliminates the problems of cell-type heterogeneity within tissue samples , ...
... , , The proven activated dendrimer for transfection , ... Features and benefits , , ... range of cell lines , Transfection in the presence of serum ... ") , High transient and stable transfection efficiencies , ...
Cached Biology Technology:Custom and library siRNA for efficient gene silencing 2Custom and library siRNA for efficient gene silencing 3Custom and library siRNA for efficient gene silencing 4Custom and library siRNA for efficient gene silencing 5Laser microdissection and nucleic acid purification - a Leica - QIAGEN , cooperation 2Laser microdissection and nucleic acid purification - a Leica - QIAGEN , cooperation 3Laser microdissection and nucleic acid purification - a Leica - QIAGEN , cooperation 4SuperFect Transfection Reagent 2SuperFect Transfection Reagent 3