Navigation Links
Older men treated for early prostate cancer live longer than those who are not

included on 44,630 men, aged 65 to 80, who were diagnosed between 1991-1999, with prostate cancer and had survived more than a year after diagnosis. All patients were followed-up until death or December 31st, 2002, the end of the study. Of the 44,630 men, 32,022 (71.8 percent) were actively treated with either surgery or radiation therapy during the first six months after diagnosis. The remaining group of 12,608 (28.3 percent) were classified as having received "observation" and did not undergo surgery, radiation or hormonal therapy.

During the 12-years of follow-up, researchers found that the patients who received treatment had a 31 percent lower risk of death. In the observation-only group, 37 percent of the patients died whereas only 23.8 percent of those in the treatment group died.

Since this was not a randomized, controlled study but a retrospective analysis of existing data, the researches had to perform extensive statistical adjustments to account for study participants differences. Even with all these differences taken into account, there was still a significant improvement in the overall survival of those men who received active treatment. "This benefit was also seen across the board in all subgroups examined, including African-American men and older men aged 75-80 at diagnosis," added Armstrong. "However, as we summarized in the study, because observational data can never completely adjust for potential selection bias and confounding, our results must be validated by rigorous randomized controlled trials of elderly men with localized prostate cancer before the findings can be used to influence treatment decisions."


'"/>

Source:University of Pennsylvania School of Medicine


Page: 1 2

Related biology news :

1. Older female fish prefer imperfect male mates, study finds
2. Older fathers more likely to have autistic children
3. More kidney cancer is detected and treated early, yet death rate rises
4. Anxiety disorders surprisingly common yet often untreated
5. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
6. Neuronal traffic jam marks early Alzheimers disease
7. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
8. In the migratory marathon, parasitized monarchs drop out early
9. Test for early detection of prostate cancer shows promise
10. PET/CT can identify new cancer lesions at early stage, allowing for prompt treatment
11. Confocal imaging promises early detection of skin cancer
Post Your Comments:
(Date:8/20/2014)... State University, the Wellcome Trust Sanger Institute and the ... Mycobacterium pinnipedii from skeletons found in Peru ... is a relative of the TB bacterium that affects ... These researchers assume that seals carried the pathogens from ... lions was unexpected" comments Sebastien Gagneux, from the Swiss ...
(Date:8/20/2014)... Health has awarded the Oklahoma Medical Research Foundation a ... anthrax and the bacteria,s effects on humans. , ... his colleagues have studied the human immune response to ... Human Immunology. The original funding came soon after anthrax-laced ... of the terrorist attacks of Sept. 11, 2001. ...
(Date:8/20/2014)... spiciness that is irresistible to some, but intolerable to ... their findings to develop a new drug candidate for ... inflammation or other problems. They reported their progress on ... in ACS, Journal of Medicinal Chemistry . , ... had pegged a compound called capsaicin as the active ...
Breaking Biology News(10 mins):$14.5 million grant awarded to continue anthrax studies 2
... release is available in German . ... been awarded this year,s Heinz Maier-Leibnitz Prizes. The relevant ... Germany,s most prestigious award for young scientists. The prizewinners ... Hanover, Dr. Wilhelm Hofmann, Psychology, University of Wrzburg, Dr. ...
... triggered by environmental stimuli and often occur in response to ... predisposition to develop these diseases, which highlights a role for ... high number of people with depression have a genetic change ... each other in the brain. Imaging of people with ...
... Williams boards ferries bound for North Carolina,s Outer Banks, the ... her the "Pollen Lady." Each spring from 2006 ... to the mainland, collecting pine pollen blown far offshore. She ... the most commonly planted tree in the southern United ...
Cached Biology News:Heinz Maier-Leibnitz Prizes 2010: 6 outstanding young researchers honored 2Heinz Maier-Leibnitz Prizes 2010: 6 outstanding young researchers honored 3Heinz Maier-Leibnitz Prizes 2010: 6 outstanding young researchers honored 4Depression associated with sustained brain signals 2Gone with the wind: Far-flung pine pollen still potent miles from the tree 2
(Date:8/20/2014)... 2014 High performance computing (HPC) ... most complete climate and Earth system model to ... issues. , Eight national laboratories, including Lawrence ... Center for Atmospheric Research, four academic institutions and ... participating national laboratories include Argonne, Brookhaven, Lawrence Berkeley, ...
(Date:8/20/2014)... 2014 Not long ago, it was ... be performed late in the development cycle – even ... regulatory trends suggest that, like many things GxP, expectations ... recent years, multiple drug sponsors have been required by ... questions during phase I/II. It’s not only clinical trial ...
(Date:8/20/2014)... 2014 GraphDB™ 6.0 ... improvements to the enterprise replication cluster, faster loading ... SOLR and Elasticsearch. This release happens to coincide ... triplestore – GraphDB™ was formerly known as OWLIM. ... only mature enterprise resilient RDF triplestore will also ...
(Date:8/19/2014)... 2014 A Geisinger researcher on a personal ... Centers for Disease Control and Prevention (CDC) award recognizing ... concern. Joseph Boscarino , Ph.D. MPH, ... team of researchers nominated for the Centers for Disease ... for Data Methods and Study Design. "Hepatitis ...
Breaking Biology Technology:New Project Is the ACME of Addressing Climate Change 2New Project Is the ACME of Addressing Climate Change 3Are Extractable and Leachables going Phase-Appropriate? New Webinar Hosted by Xtalks 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 2Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 3Ontotext Improves Its RDF Triplestore, GraphDB™ 6.0: Enterprise Resilience, Faster Loading Speeds and Connectors to Full-Text Search Engines Top the List of Enhancements 4Geisinger investigator nominated for federal award 2Geisinger investigator nominated for federal award 3
... , ... WX ), a,leading pharmaceutical, biotechnology, and medical-device research ... United States,announced that it had been selected to the ... consecutive year. The list recognizes the 50,fastest-growing companies in ...
... , DURHAM, N.C., Nov. 27 ... water-soluble carbon nanotube-based cancer drug delivery system in Hyderabad, India. ... walls that allows for conjugation with cancer drugs, was developed ... conjugated carbon nanotubes serves as a drug delivery vehicle with ...
... , BOSTON, Nov. 25 Biotech firm Replikins Ltd., ... pandemic through the prediction, outbreak, and progress of the current H1N1 ... new data shows that the lethality of the H1N1 ("Swine Flu") ... the virus,s current outbreak in the spring of 2009 to resting ...
Cached Biology Technology:WuXi PharmaTech Named in Deloitte Technology Fast 50 China 2009 List for the Fifth Consecutive Year 2North Carolina Based Cromoz Inc. Launches Carbon Nanotechnology for Target Drug Delivery System in Cancer Treatment in Hyderabad, India 2Biological H1N1 Vaccines: Too Little, Too Late 2Biological H1N1 Vaccines: Too Little, Too Late 3Biological H1N1 Vaccines: Too Little, Too Late 4Biological H1N1 Vaccines: Too Little, Too Late 5
... isolated fromStreptomyces griseolusthat inhibits protein synthesis. ... in eukaryote ribosomes. Reported to induce ... including promyelocytic leukemia cells, Jurkat cells, ... Initiates intracellular signals and immediate early ...
... RC DC protein assay kit I provides reagents ... in the presence of reducing agents and detergents. ... assay. The kit includes reagents and standards sufficient ... I, 250 ml RC reagent II, 250 ml ...
Recommended for use as a cell culture substratum at 0.1-0.2 mg/cm 2 or 5-10 μl/cm 2 . Optimal concentration depends on cell type as well as the application or research objectives. Type B...
... state-of-the-art separation system using the asymmetric flow ... integrates easily with Wyatts multi-angle light scattering ... as the Optilab DSP. The combined system ... of the particles/molecules separated by the AFFF ...
Biology Products: