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Old memory traces in brain may trigger chronic pain

He said the drug potentially may lower the amount of standard analgesics people have to use.

In Apkarian’s previous study, published in late 2006, he revealed that chronic back pain appears in a different part of the brain than the discomfort of burning your finger, for example. With a functional MRI, he found that chronic back pain shows up in the prefrontal cortex. By contrast, the acute sensory pain of the burned finger appears in the sensory part of the thalamus.

Apkarian also found that the longer a person has been suffering from chronic pain, the more activity in the prefrontal cortex. He was able to predict the years of their suffering from the MRI.

“It’s cumulative memory,” he explained. “I can predict with 90 percent accuracy how many years they have been living in that pain without even asking them the question.”


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Source:Northwestern University


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