Navigation Links
ORNL leading effort to help harness power of Shewanella

Tremendous amounts of data being generated about a microbe adept at bioremediation will be more efficiently organized and shared through a new $3 million project headed by Oak Ridge National Laboratory.

The award by the Department of Energy's Office of Science builds upon advances made through a three-year consortium whose members have already sequenced the genome ?the genetic makeup ?of seven strains of the Shewanella, a relatively common microbe with diverse capabilities. Working with the Joint Genome Institute, researchers hope to sequence the remaining eight strains by the end of 2006.

"Our goals are to gain a better understanding of the Shewanella mechanisms for metal contaminants reduction and other bioremediation applications, and develop a system that makes the information readily available to the research community," said Ed Uberbacher, a member of ORNL's Life Sciences Division and leader of the project.

When the work is complete, researchers worldwide will be able to query across the many individual research domains and projects, link to analysis applications, visualize data in a cell systems context and produce new knowledge. This will be accomplished while minimizing the effort, time and complexity to participating laboratories, Uberbacher said.

This effort could have a dramatic impact on the bioremediation mission involving approximately 2 trillion gallons of heavy metal contaminated groundwater and 75 million cubic meters of soil and subsurface sediment at various DOE and other sites around the nation.

"Biological knowledge emerging from genome sequencing efforts and new programs such as Genomics: Genomes to Life have the potential to put microbial cells and communities or cell components to work to meet the challenges of this critical DOE mission," Uberbacher said.

This three-year project, officially known as "An Integrated Knowledge Resource for the Shewanella Federation," will play a key role in helping researchers gain a more complete understanding of the response systems in organisms such as Shewanella and how they respond to changes in their environment. This can be achieved through a combination of many different methods, including sampling of strains present at DOE waste sites, characterization of in situ and mutant physiologies and exploration of conditions conducive to optimal reduction of metals.

This is one of six recently announced DOE projects aimed at increasing knowledge of microbes and microbial communities with potential applications in bioremediation, ethanol and hydrogen production, cleanup of former nuclear weapons production sites and minimizing global warming by controlling the cycling of atmospheric carbon dioxide.


'"/>

Source:DOE/Oak Ridge National Laboratory


Related biology news :

1. Enzyme allows B cells to resist death, leading to leukemia
2. Scientists document complex genomic events leading to the birth of new genes
3. Genetic links could unlock clues to leading cause of blindness
4. Why do aneurysms form? New studies suggest leading role for white blood cells
5. Jefferson scientists identify gene defect leading to abnormal skin development and cancer
6. Twin studies reveal genetic components leading to cardiac and kidney disease
7. Climate change could trigger boom and bust population cycles leading to extinction
8. Worlds leading scientists announce creation of Encyclopedia of Life
9. International HapMap consortium expands mapping effort
10. Hopkins AIDS experts issue warning about global efforts to provide drug therapies
11. NHGRI expands effort to revolutionize sequencing technologies
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/23/2017)... -- Hunova, the first robotic gym for the rehabilitation and functional motor sense ... Genoa, Italy . The first 30 robots will be available ... USA . The technology was developed and patented at the IIT ... Movendo Technology thanks to a 10 million euro investment from entrepreneur Sergio ... ...
(Date:4/24/2017)... WASHINGTON , April 24, 2017 ... counsel and partner with  Identity Strategy Partners, LLP ... "With or without President Trump,s March 6, ... Foreign Terrorist Entry , refugee vetting can be instilled ... refugee resettlement. (Right now, all refugee applications are ...
(Date:4/13/2017)... MONICA, Calif. , April 13, 2017 ... New York will feature emerging and evolving ... Summits. Both Innovation Summits will run alongside the expo ... of speaker sessions, panels and demonstrations focused on trending ... coast,s largest advanced design and manufacturing event will take ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... The ... three Winners and six Finalists of the 2017 Blavatnik Regional Awards for Young ... Family Foundation and administered by the New York Academy of Sciences to honor ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... Rosalind™, the first-ever genomics analysis platform specifically designed for life science researchers ... honor of pioneering researcher Rosalind Franklin, who made a major contribution to ...
(Date:10/11/2017)... ... October 11, 2017 , ... Proscia Inc ., ... a Webinar titled, “Pathology is going digital. Is your lab ready?” with Dr. ... best practices and how Proscia improves lab economics and realizes an increase in ...
(Date:10/11/2017)... ... October 11, 2017 , ... Singh Biotechnology today announced ... to SBT-100, its novel anti-STAT3 (Signal Transducer and Activator of Transcription 3) B ... to cross the cell membrane and bind intracellular STAT3 and inhibit its function. ...
Breaking Biology Technology: