Navigation Links
Novel vaccine shows promise against early-stage breast cancer

A diagnosis of breast cancer has taken on a new meaning in the past 10 years, as research has produced a host of new therapies and detection techniques, significantly improving long-term survival for women who have been fighting the disease. To build on these successes, researchers are now harnessing what they have learned about treating breast cancer and applying it to possible methods of prevention to reduce the total incidence of the disease. One study presented today at the American Association for Cancer Research's Frontiers in Cancer Prevention Research meeting in Boston looks at a specific target in the fight against breast cancer and evaluates a potential vaccine that is yielding promising results for women who are at high-risk for the disease.

Targeted immunoediting of critical pathways responsible for breast cancer development: treatment of early breast cancer using HER-2/neu pulsed dendritic cells

Multiple genetic targets have been discovered that may help fight breast cancer, including BRCA, estrogen receptors, and HER-2/neu, all of which have been known to predict the severity of disease, recurrence and overall survival. Developing novel therapies that target these specific genetic variances may be extremely beneficial in preventing breast cancer for many women.

In this study, researchers investigated a potential vaccine that targets HER-2/neu over-expression in early stage breast cancer, known as DCIS (ductal carcinomas in situ, or early stage cancer formation in the breast's milk ducts). It is estimated at 50-60 percent of DCIS is directly related to HER-2/neu over-expression.

Patients with HER-2/neu overexpression were given a therapy of dendritic cells (DC, which work with the B- and T-cells to trigger immune responses) that were treated with HER-2/neu to evoke an immune response. The participants received four weekly vaccinations into normal lymph nodes in their groins and were evaluated both pre- and po
'"/>

Source:American Association for Cancer Research


Page: 1 2

Related biology news :

1. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
2. Novel technology detects human DNA mutations
3. Novel antiviral technology inhibits RSV infection in mice
4. Novel Enzyme Shows Potential As An Anti-HIV Target
5. Novel Therapy Tested in Mice Could Chase Away Cat Allergies
6. Discovery Could Lead To Novel Approaches In HIV Treatment
7. Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
8. Research Using Mouse Models Reveals A Novel Key Player In The Initiation Of Colon Cancer
9. Novel gene-silencing nanoparticles shown to inhibit Ewings sarcoma
10. Novel live reporting system to track cells
11. Field of beams - Novel system uses polarized light pulses to reveal crop health
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Novel vaccine shows promise against early stage breast cancer

(Date:9/11/2014)... of Northumberland and Durham" by Nathaniel John Winch is ... as an example of combining modern information technology together ... resource and data re-use. This publication will be supporting ... can be seen as a model for other regions ... marries the meticulous detail of old books with the ...
(Date:9/11/2014)... URBANA, Ill. Chicago residents today might have had ... boundary of Illinois had been approved. It was a ... to just south of the Rock and Mississippi River ... that had the proposed northern border not been changed, ... population and footprint with the northern 51 miles of ...
(Date:9/11/2014)... September 2014 Patients with Parkinson,s disease (PD) ... which could contribute to poor nutrition and place ... also suggested that PD is associated with low ... report published in the Journal of Parkinson,s ... mild-to-moderate PD, finding that the incidence or risk ...
Breaking Biology News(10 mins):Re-publication of 'Flora of Northumberland and Durham' (1831): A dramatic account of change 2Re-publication of 'Flora of Northumberland and Durham' (1831): A dramatic account of change 3Original northern border of Illinois was south of Chicago and Lake Michigan 2Original northern border of Illinois was south of Chicago and Lake Michigan 3Few mild-to-moderate Parkinson's disease patients suffer from malnutrition, yet almost one-third are at risk 2
... Margaret Hospital have created an organic nanoparticle that is ... uses light and heat to treat cancer and deliver ... properties). The findings, published online today in ... unlike other nanoparticles, the new nanoparticle has a unique ...
... and Elke Mhlberger, PhD, both associate professors of microbiology ... a commentary about viruses for Microbiology Today, the monthly ... the largest microbiological society in Europe. The article focuses ... their perspective on what is necessary to evolve to ...
... oxide is a potent greenhouse gas and a precursor ... ozone. Intensively managed, grazed pastures are responsible for an ... Biochar is potentially a mitigation option for reducing the ... can be sequestered in the soil. Biochar also has ...
Cached Biology News:PMH researchers create an organic nanoparticle that uses sound and heat to find and treat tumors 2BUSM faculty author commentary on the global challenges of emerging viral infections 2Can biochar help suppress greenhouse gases? 2
(Date:9/11/2014)... week in Science , the collaboration led by ... Sir Andre Geim report a material in which electrons ... to sailboats driven diagonally to the wind. , The ... from carbon but with a difference. It is ... it on top of boron nitride, also known as ...
(Date:9/11/2014)... , Sept. 11, 2014  Lakewood-Amedex ... pharmaceuticals, announced today that the United States ... ,Notice of Allowance, for patent application 11/673,486 ...  The ,486 patent application relates to the ... gene-silencing and can be designed to treat ...
(Date:9/11/2014)... Until recently, pets suffering from arthritic ailments ... their pain. Pill therapies are costly, can be harmful ... , The procedure uses adult (not embryonic) animal ... regenerative healing power. MediVet's equipment enable veterinarians to remove ... stem cells, then activate and inject the cells into ...
(Date:9/11/2014)... YORK, NY (PRWEB) September 11, 2014 Entries ... Choice Awards—the only awards where peers and colleagues within the ... the Pharma Choice Awards recognize the very best in healthcare ... are judged by peers in the health and wellness industry. ... to vote for the top campaigns in each category. ...
Breaking Biology Technology:New species of electrons can lead to better computing 2Lakewood-Amedex Receives Notice Of Allowance From The United States Patent and Trademark Office (USPTO) For A New Patent Covering Its nanoRNA Gene-Silencing Technology 2Lakewood-Amedex Receives Notice Of Allowance From The United States Patent and Trademark Office (USPTO) For A New Patent Covering Its nanoRNA Gene-Silencing Technology 3MediVet America Secures Exclusive Worldwide License with Nanofiber Veterinary 2PM360 Now Accepting Entries for 2014 Pharma Choice Awards 2
... Vaccine Indicated to Prevent, Rotavirus Caused by ... of the Vaccination by Four Months of Age, with ... 20 ,GlaxoSmithKline (NYSE: GSK ) announced today that ... Biological Products Advisory,Committee (VRBPAC) provided a favorable recommendation for ...
... Cadence Pharmaceuticals,Inc. (Nasdaq: CADX ), a ... product candidates principally,for use in the hospital setting, ... direct offering of approximately 9.2,million shares of common ... for gross,proceeds of $49.3 million., "The proceeds ...
... been miniaturized to take up less space and weigh ... conversion electronics on the James Webb Space Telescope being ... analog signals to digital signals and provide better images ... have been miniaturized from a volume of about one ...
Cached Biology Technology:GSK Receives Favorable Recommendation by FDA Advisory Committee for Rotarix(R) (Rotavirus Vaccine, Live, Oral) 2GSK Receives Favorable Recommendation by FDA Advisory Committee for Rotarix(R) (Rotavirus Vaccine, Live, Oral) 3GSK Receives Favorable Recommendation by FDA Advisory Committee for Rotarix(R) (Rotavirus Vaccine, Live, Oral) 4Cadence Pharmaceuticals Completes $49.3 Million Registered Direct Offering 2Cadence Pharmaceuticals Completes $49.3 Million Registered Direct Offering 3Amazing minaturized 'SIDECAR' drives Webb telescope's signal 2Amazing minaturized 'SIDECAR' drives Webb telescope's signal 3
...
CoverWell imaging chamber gasket with adhesive, one chamber, 20 mm diameter, 1.0 mm deep *set of 40* Cell Biology Imaging Tools and Accessories Microscope Slide Accessories...
...
... Apoptosis Assay Kit #4 detects apoptosis ... in the permeability of cell membranes. This ... and propidium iodide nucleic acid stains. YO-PRO-1 ... of apoptotic cells and labels them with ...
Biology Products: